Familial hypercholesterolemia with early coronary atherosclerotic heart disease: A case report

Luo,Yanhong; Zheng,Min; Zhang,Yutin; He,Shuang; Zhang,Lei; Sun,Huichao; Liu,Xiaoyan; Tan,Tao; Zhu,Hua; He,Jianfeng

doi:10.3892/etm.2019.7653

August-2019 Volume 18 Issue 2

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August-2019 Volume 18 Issue 2

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Case Report Open Access

Familial hypercholesterolemia with early coronary atherosclerotic heart disease: A case report

Authors:
- Yanhong Luo
- Min Zheng
- Yutin Zhang
- Shuang He
- Lei Zhang
- Huichao Sun
- Xiaoyan Liu
- Tao Tan
- Hua Zhu
- Jianfeng He
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Affiliations: Department of Endocrinology and Genetic Metabolism, Children's Hospital Chongqing Medical University, Chongqing 400014, P.R. China, Department of Cardiology, Children's Hospital Chongqing Medical University, Chongqing 400014, P.R. China, Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA

Copyright: © Luo et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 981-986
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Published online on: June 10, 2019

https://doi.org/10.3892/etm.2019.7653
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Abstract

Patients with familial hypercholesterolemia usually present with high levels of serum low-density lipoprotein, xanthomas and early coronary artery disease. A 13 years old female patient was admitted to Children's Hospital of Chongqing Medical University presenting symptoms of heart failure. Laboratory tests showed that her cholesterol and low-density lipid levels were extremely high. Electrocardiogram test revealed that she had sinus tachycardia, QT lengthening and ST‑T change. Multiple cardiac function abnormalities were diagnosed by echocardiogram. Multiple coronary artery stenosis was determined by computed tomography angiography. After the combination of lipid lowering, anti‑thrombosis, and cardiac remodeling therapies, the patient's symptoms were significantly improved and the patient was discharged.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Familial hypercholesterolemia with early coronary atherosclerotic heart disease: A case report

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