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Case Report

Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report

  • Authors:
    • Xin Zhang
    • Xingbin Liu
  • View Affiliations / Copyright

    Affiliations: Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
  • Pages: 2238-2242
    |
    Published online on: July 19, 2019
       https://doi.org/10.3892/etm.2019.7796
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Abstract

Mid‑ventricular obstructive hypertrophic cardiomyopathy (MVOHC) with apical aneurysm is a rare type of cardiomyopathy. It is associated with an elevated risk of ventricular arrhythmias, thromboembolism, heart failure and sudden cardiac death. The present case study reports on a patient with MVOHC and apical aneurysm who developed ventricular arrhythmias and heart failure. The patient received an implantable cardioverter defibrillator for prevention of fatal arrhythmias. Ventricular tachycardia was terminated by increased doses of amiodarone and β‑blocker. Transthoracic echocardiography indicated a mid‑ventricular gradient of 64 mmHg. The patient refused surgical treatment and opted for alcohol septal ablation (ASA). At the 6‑month follow‑up, a rebound of the gradient following ASA was observed on echocardiography. In the present study, timely recognition of MVOHC with apical aneurysm led to prompt defibrillator implantation for prophylaxis regarding further malignant arrhythmias. Surgical management should be considered in symptomatic patients with MVOHC and apical aneurysm.
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1 

Veselka J, Anavekar NS and Charron P: Hypertrophic obstructive cardiomyopathy. Lancet. 389:1253–1267. 2017. View Article : Google Scholar : PubMed/NCBI

2 

Criley JM and Siegel RJ: Has ‘obstruction’ hindered our understanding of hypertrophic cardiomyopathy? Circulation. 72:1148–1154. 1985. View Article : Google Scholar : PubMed/NCBI

3 

Maron BJ: Hypertrophic cardiomyopathy: A systematic review. JAMA. 287:1308–1320. 2002. View Article : Google Scholar : PubMed/NCBI

4 

Wigle ED, Sasson Z, Henderson MA, Ruddy TD, Fulop J, Rakowski H and Williams WG: Hypertrophic cardiomyopathy. The importance of the site and the extent of hypertrophy. A review. Prog Cardiovasc Dis. 28:1–83. 1985. View Article : Google Scholar : PubMed/NCBI

5 

Maron MS, Finley JJ, Bos JM, Hauser TH, Manning WJ, Haas TS, Lesser JR, Udelson JE, Ackerman MJ and Maron BJ: Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathy. Circulation. 118:1541–1549. 2008. View Article : Google Scholar : PubMed/NCBI

6 

Rowin EJ, Maron BJ, Haas TS, Garberich RF, Wang W, Link MS and Maron MS: Hypertrophic cardiomyopathy with left ventricular apical aneurysm: Implications for risk stratification and management. J Am Coll Cardiol. 69:761–773. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, Fonarow GC, Geraci SA, Horwich T, Januzzi JL, et al: 2013 ACCF/AHA guideline for the management of heart failure: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 62:e147–e239. 2013. View Article : Google Scholar : PubMed/NCBI

8 

Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, et al: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 124:e783–e831. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Minami Y, Kajimoto K, Terajima Y, Yashiro B, Okayama D, Haruki S, Nakajima T, Kawashiro N, Kawana M and Hagiwara N: Clinical implications of midventricular obstruction in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol. 57:2346–2355. 2011. View Article : Google Scholar : PubMed/NCBI

10 

Efthimiadis GK, Pagourelias ED, Parcharidou D, Gossios T, Kamperidis V, Theofilogiannakos EK, Pappa Z, Meditskou S, Hadjimiltiades S, Pliakos C, et al: Clinical characteristics and natural history of hypertrophic cardiomyopathy with midventricular obstruction. Circ J. 77:2366–2374. 2013. View Article : Google Scholar : PubMed/NCBI

11 

Authors/Task Force members, ; Elliott PM, Anastasakis A, Borger MA, Borggrefe M, Cecchi F, Charron P, Hagege AA, Lafont A, Limongelli G, et al: 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: The task force for the diagnosis and management of hypertrophic cardiomyopathy of the European Society of Cardiology (ESC). Eur Heart J. 35:2733–2779. 2014. View Article : Google Scholar : PubMed/NCBI

12 

Liang JJ, Santangeli P and Callans DJ: Long-term outcomes of ventricular tachycardia ablation in different types of structural heart disease. Arrhythm Electrophysiol Rev. 4:177–183. 2015. View Article : Google Scholar : PubMed/NCBI

13 

Mantica M, Della Bella P and Arena V: Hypertrophic cardiomyopathy with apical aneurysm: A case of catheter and surgical therapy of sustained monomorphic ventricular tachycardia. Heart. 77:481–483. 1997. View Article : Google Scholar : PubMed/NCBI

14 

Tokuda M, Kojodjojo P, Tung S, Tedrow UB, Nof E, Inada K, Koplan BA, Michaud GF, John RM, Epstein LM and Stevenson WG: Acute failure of catheter ablation for ventricular tachycardia due to structural heart disease: Causes and significance. J Am Heart Assoc. 2:e0000722013. View Article : Google Scholar : PubMed/NCBI

15 

Maron BJ, Maron MS, Wigle ED and Braunwald E: The 50-year history, controversy, and clinical implications of left ventricular outflow tract obstruction in hypertrophic cardiomyopathy from idiopathic hypertrophic subaortic stenosis to hypertrophic cardiomyopathy: From idiopathic hypertrophic subaortic stenosis to hypertrophic cardiomyopathy. J Am Coll Cardiol. 54:191–200. 2009. View Article : Google Scholar : PubMed/NCBI

16 

Tengiz I, Ercan E, Alioglu E and Turk UO: Percutaneous septal ablation for left mid-ventricular obstructive hypertrophic cardiomyopathy: A case report. BMC Cardiovasc Disord. 6:152006. View Article : Google Scholar : PubMed/NCBI

17 

Spirito P, Rossi J and Maron BJ: Alcohol septal ablation: In which patients and why? Ann Cardiothorac Surg. 6:369–375. 2017. View Article : Google Scholar : PubMed/NCBI

18 

Seggewiss H and Faber L: Percutaneous septal ablation for hypertrophic cardiomyopathy and mid-ventricular obstruction. Eur J Echocardiogr. 1:277–280. 2000. View Article : Google Scholar : PubMed/NCBI

19 

Yang YJ, Fan CM, Yuan JQ, Wang SY, Song YH, Qiao SB, You SJ, Wang ZM, Duan FJ and Li YS: Effectiveness of alcohol septal ablation versus transaortic extended myectomy in hypertrophic cardiomyopathy with midventricular obstruction. J Interv Cardiol. 29:619–627. 2016. View Article : Google Scholar : PubMed/NCBI

20 

Nguyen A, Schaff HV, Nishimura RA, Dearani JA and Ommen SR: Early outcomes of repair of left ventricular apical aneurysms in patients with hypertrophic cardiomyopathy. Circulation. 136:1979–1981. 2017. View Article : Google Scholar : PubMed/NCBI

21 

Opie LH, Commerford PJ, Gersh BJ and Pfeffer MA: Controversies in ventricular remodelling. Lancet. 367:356–367. 2006. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang X and Liu X: Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report. Exp Ther Med 18: 2238-2242, 2019.
APA
Zhang, X., & Liu, X. (2019). Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report. Experimental and Therapeutic Medicine, 18, 2238-2242. https://doi.org/10.3892/etm.2019.7796
MLA
Zhang, X., Liu, X."Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report". Experimental and Therapeutic Medicine 18.3 (2019): 2238-2242.
Chicago
Zhang, X., Liu, X."Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report". Experimental and Therapeutic Medicine 18, no. 3 (2019): 2238-2242. https://doi.org/10.3892/etm.2019.7796
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang X and Liu X: Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report. Exp Ther Med 18: 2238-2242, 2019.
APA
Zhang, X., & Liu, X. (2019). Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report. Experimental and Therapeutic Medicine, 18, 2238-2242. https://doi.org/10.3892/etm.2019.7796
MLA
Zhang, X., Liu, X."Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report". Experimental and Therapeutic Medicine 18.3 (2019): 2238-2242.
Chicago
Zhang, X., Liu, X."Ventricular tachycardia and heart failure in a patient of mid‑ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: A case report". Experimental and Therapeutic Medicine 18, no. 3 (2019): 2238-2242. https://doi.org/10.3892/etm.2019.7796
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