Rapid progression and recovery of massive gastric mucosal damage complicated by Henoch‑Schönlein purpura in a patient with liver cirrhosis: A case report

Gweon,Tae‑Geun; Kwon,Jung  Hyun

doi:10.3892/etm.2019.7815

September-2019 Volume 18 Issue 3

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September-2019 Volume 18 Issue 3

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Case Report Open Access

Rapid progression and recovery of massive gastric mucosal damage complicated by Henoch‑Schönlein purpura in a patient with liver cirrhosis: A case report

Authors:
- Tae‑Geun Gweon
- Jung Hyun Kwon
View Affiliations / Copyright

Affiliations: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon 21431, Republic of Korea

Copyright: © Gweon et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 2051-2054
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Published online on: July 26, 2019

https://doi.org/10.3892/etm.2019.7815
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Abstract

Endoscopic findings associated with gastric ischemia include friable gastric mucosa, irregular ulceration, petechiae and purpura. The etiology of gastric ischemia includes shock, sepsis, thrombosis, embolism and vasculitis. Henoch‑Schönlein purpura (HSP) is a leukocytoclastic vasculitis that affects small vessels in the skin, kidney and gastrointestinal (GI) tract. Rapid progression of HSP manifested with acute gastric mucosal bleeding has been rarely reported. The present case study reports on a patient who had undergone endoscopic variceal ligation for esophageal varix bleeding and the gastric mucosa exhibited no evidence of HSP. After 9 days, reexamination using endoscopy to check for new‑onset hematemesis revealed massive necrosis in the gastric mucosa, friable mucosal tissue and acute ischemic GI bleeding. The patient was treated with corticosteroid injections for 7 days, which caused a marked regression of the hemorrhagic gastric mucosa. The present case study reported on this patient with acute GI bleeding caused by HSP who was successfully treated with corticosteroids.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Rapid progression and recovery of massive gastric mucosal damage complicated by Henoch‑Schönlein purpura in a patient with liver cirrhosis: A case report

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