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Review

Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review)

  • Authors:
    • Ovidiu Gabriel Bratu
    • Camelia Cristina Diaconu
    • Dan Liviu Dorel Mischianu
    • Traian Constantin
    • Ana Maria Alexandra Stanescu
    • Simona Gabriela Bungau
    • Florentina Ionita‑Radu
    • Radu Dragos Marcu
  • View Affiliations / Copyright

    Affiliations: University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, Romania, University of Oradea, Faculty of Medicine and Pharmacy, Department of Pharmacy, 410073 Oradea, Romania, Gastroenterology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania
  • Pages: 5021-5025
    |
    Published online on: August 20, 2019
       https://doi.org/10.3892/etm.2019.7916
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Abstract

Prostate cancer is the second most common form of cancer in men in Europe. The primary treatment of this type of cancer is radical prostatectomy, which has shown good oncological results. Radical prostatectomy (open, laparoscopic or robotic) has high success and low morbidity rates in patients with localized prostate cancer. The life expectancy is >10 years after radical prostatectomy. Studies have shown that ~20%‑30% of the patients who have undergone radical prostatectomy can develop biochemical recurrence, which is monitored by using the value of the prostate‑specific antigen (PSA). In some cases (patients with high‑risk prostate cancer), adjuvant therapy after radical prostatectomy, such as radiotherapy or androgen deprivation therapy, can significantly reduce the risk of biochemical recurrence. The optimal management of recurrent disease remains uncertain. Recent literature was systematically reviewed regarding the management of biochemical recurrence and to compare clinical experience in literature studies.
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Copy and paste a formatted citation
Spandidos Publications style
Bratu OG, Diaconu CC, Mischianu DL, Constantin T, Stanescu AM, Bungau SG, Ionita‑Radu F and Marcu RD: Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review). Exp Ther Med 18: 5021-5025, 2019.
APA
Bratu, O.G., Diaconu, C.C., Mischianu, D.L., Constantin, T., Stanescu, A.M., Bungau, S.G. ... Marcu, R.D. (2019). Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review). Experimental and Therapeutic Medicine, 18, 5021-5025. https://doi.org/10.3892/etm.2019.7916
MLA
Bratu, O. G., Diaconu, C. C., Mischianu, D. L., Constantin, T., Stanescu, A. M., Bungau, S. G., Ionita‑Radu, F., Marcu, R. D."Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review)". Experimental and Therapeutic Medicine 18.6 (2019): 5021-5025.
Chicago
Bratu, O. G., Diaconu, C. C., Mischianu, D. L., Constantin, T., Stanescu, A. M., Bungau, S. G., Ionita‑Radu, F., Marcu, R. D."Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review)". Experimental and Therapeutic Medicine 18, no. 6 (2019): 5021-5025. https://doi.org/10.3892/etm.2019.7916
Copy and paste a formatted citation
x
Spandidos Publications style
Bratu OG, Diaconu CC, Mischianu DL, Constantin T, Stanescu AM, Bungau SG, Ionita‑Radu F and Marcu RD: Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review). Exp Ther Med 18: 5021-5025, 2019.
APA
Bratu, O.G., Diaconu, C.C., Mischianu, D.L., Constantin, T., Stanescu, A.M., Bungau, S.G. ... Marcu, R.D. (2019). Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review). Experimental and Therapeutic Medicine, 18, 5021-5025. https://doi.org/10.3892/etm.2019.7916
MLA
Bratu, O. G., Diaconu, C. C., Mischianu, D. L., Constantin, T., Stanescu, A. M., Bungau, S. G., Ionita‑Radu, F., Marcu, R. D."Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review)". Experimental and Therapeutic Medicine 18.6 (2019): 5021-5025.
Chicago
Bratu, O. G., Diaconu, C. C., Mischianu, D. L., Constantin, T., Stanescu, A. M., Bungau, S. G., Ionita‑Radu, F., Marcu, R. D."Therapeutic options in patients with biochemical recurrence after radical prostatectomy (Review)". Experimental and Therapeutic Medicine 18, no. 6 (2019): 5021-5025. https://doi.org/10.3892/etm.2019.7916
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