High-frequency ultrasonography of psoriatic skin: A non-invasive technique in the evaluation of the entire skin of patients with psoriasis: A pilot study

  • Authors:
    • Mihaela Cristina Șomlea
    • Andreea Nicoleta Boca
    • Alexandra Dana Pop
    • Roxana Flavia Ilieș
    • Stefan Cristian Vesa
    • Anca Dana Buzoianu
    • Alexandru Tătaru
  • View Affiliations

  • Published online on: October 29, 2019     https://doi.org/10.3892/etm.2019.8140
  • Pages: 4981-4986
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Abstract

Psoriasis is a chronic, systemic, inflammatory disorder which accelerates the life process of skin cells, based on a genetically induced deviant immune response. High‑frequency ultrasonography (HF-USG) is a painless, non‑invasive imaging technique that can be performed and repeated whenever the need arises. We evaluated lesional and non‑lesional skin of psoriatic patients with the use of HF-USG, focusing on the immune‑induced inflammation and skin thickness. Previous studies suggested that HF-USG, being a non‑invasive technique, is useful as an aid to clinical evaluation of the severity of psoriatic plaques. Our goal was to determine whether the skin of psoriatic patients is influenced by the background or habits of the patients. The study included a total of 27 patients affected by psoriasis vulgaris. The thickness of the epidermis and dermis and the skin echogenicity were documented for the active plaques, as well as for the non‑affected skin of all the patients included in the study, using a high‑frequency ultrasonographic system. The patient's local background, sex, family history of psoriasis, smoking habits and sun exposure were analyzed. HF-USG of the psoriatic plaques exposes a three‑band structure that is easily distinguished from the surrounding unaffected skin, due to a hypoechoic band in the upper dermis. Although not specific for psoriasis, it is a strong marker of inflammation. The obtained results confirm that, indeed, skin thickness is greater in lesional skin compared to non‑lesional skin, by a mean of 1,180 µm (±340 µm). We consider that skin HF-USG should be used as a quantitative method in the clinical evaluation of the patients with psoriasis and may help as an objective means of assessing inflammation in lesional skin.

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December 2019
Volume 18 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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APA
Șomlea, M.C., Boca, A.N., Pop, A.D., Ilieș, R.F., Vesa, S.C., Buzoianu, A.D., & Tătaru, A. (2019). High-frequency ultrasonography of psoriatic skin: A non-invasive technique in the evaluation of the entire skin of patients with psoriasis: A pilot study. Experimental and Therapeutic Medicine, 18, 4981-4986. https://doi.org/10.3892/etm.2019.8140
MLA
Șomlea, M. C., Boca, A. N., Pop, A. D., Ilieș, R. F., Vesa, S. C., Buzoianu, A. D., Tătaru, A."High-frequency ultrasonography of psoriatic skin: A non-invasive technique in the evaluation of the entire skin of patients with psoriasis: A pilot study". Experimental and Therapeutic Medicine 18.6 (2019): 4981-4986.
Chicago
Șomlea, M. C., Boca, A. N., Pop, A. D., Ilieș, R. F., Vesa, S. C., Buzoianu, A. D., Tătaru, A."High-frequency ultrasonography of psoriatic skin: A non-invasive technique in the evaluation of the entire skin of patients with psoriasis: A pilot study". Experimental and Therapeutic Medicine 18, no. 6 (2019): 4981-4986. https://doi.org/10.3892/etm.2019.8140