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Article Open Access

Novel detachable stents for the treatment of benign esophageal strictures

  • Authors:
    • Liang Shang
    • Qing‑Shan Pei
    • Dan Xu
    • Ji‑Yong Liu
    • Jin Liu
  • View Affiliations / Copyright

    Affiliations: Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China, Endoscopy Room, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China
    Copyright: © Shang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 115-122
    |
    Published online on: November 12, 2019
       https://doi.org/10.3892/etm.2019.8190
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Abstract

The radial force of esophageal stents may not completely change during extraction and therefore, the procedure of stent removal may cause tissue damage. The present study reports the manufacture of 2 novel detachable stents, which were designed to reduce tissue damage through their capacity to be taken or fall apart prior to removal and evaluated the supporting properties of these stents and the extent of local mucosal injury during their removal. The stents were manufactured by braiding, heat‑setting, coating and connecting. The properties of the stents were evaluated by determining the following parameters: Expansion point, softening point, stent flexibility, radial compression ratio and radial force. A total of 18 rabbits with induced esophageal stricture were randomly assigned to 3 groups as follows: Detachable stent (DS) group, biodegradable stent (BS) group and control group. The stricture rate, complications, survival, degradation and stent removal were observed over 8 weeks. The stents of the DS and BS groups provided a similar supporting effect. The stricture rate, incidence of complications and survival were also similar between the 2 groups, while significant differences were noted between the DS and control groups and between the BS and control groups. In the BS group, the stents were degraded and moved to the stomach within 7 weeks (2 in 6 weeks and 3 in 7 weeks). The debris was extracted using biopsy forceps. In the DS group, all stents were easy to remove and 2 cases exhibited minor hemorrhage. In conclusion, the 2 types of novel detachable stent provided an equally efficient supporting effect in vitro and in vivo and may reduce the incidence of secondary injury during stent removal.
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1 

Hasan M and Maple JT: Traversing difficult esophageal strictures from the retrograde apprpach. Tech Gastrointest Endosc. 10:149–154. 2008. View Article : Google Scholar

2 

Shah JN: Benign refractory esophageal strictures: Widening the endoscopist's role. Gastrointest Endosc. 63:164–167. 2006. View Article : Google Scholar : PubMed/NCBI

3 

Luchtefeld MA, Milsom JW, Senagore A, Surrell JA and Mazier WP: Colorectal anastomotic stenosis: Results of a survey of the ASCRS membership. Dis Colon Rectum. 32:733–736. 1989. View Article : Google Scholar : PubMed/NCBI

4 

Mori H, Rafiq K, Kobara H, Fujihara S, Nishiyama N, Oryuu M, Suzuki Y and Masaki T: Steroid permeation into the artificial ulcer by combined steroid gel application and balloon dilatation: Prevention of esophageal stricture. J Gastroenterol Hepatol. 28:999–1003. 2013. View Article : Google Scholar : PubMed/NCBI

5 

Isomoto H, Yamaguchi N, Nakayama T, Hayashi T, Nishiyama H, Ohnita K, Takeshima F, Shikuwa S, Kohno S and Nakao K: Management of esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma. BMC Gastroenterol. 11:462011. View Article : Google Scholar : PubMed/NCBI

6 

Kobayashi S, Kanai N, Ohki S, Takagi R, Yamaguchi N, Isomoto H, Kasai Y, Hosoi T, Nakao K, Eguchi S, et al: Prevention of esophageal strictures after endoscopic submucosal dissection. World J Gastroenterol. 20:15098–15109. 2014. View Article : Google Scholar : PubMed/NCBI

7 

Yamashina T, Uedo N, Fujii M, Ishihara R, Mikamori M, Motoori M, Yano M and Iishi H: Delayed perforation after intralesional triamcinolone injection for esophageal stricture following endoscopic submucosal dissection. Endoscopy. 45 (Suppl 2) UCTN:E922013. View Article : Google Scholar : PubMed/NCBI

8 

Tang J, Ye S, Ji X, Liu F and Li Z: Deployment of carboxymethyl cellulose sheets to prevent esophageal stricture after full circumferential endoscopic submucosal dissection: A porcine model. Dig Endosc. 30:608–615. 2018. View Article : Google Scholar : PubMed/NCBI

9 

Park JH, Song HY, Park JY, Kim JH, Kim YH, Kim JH and Kim SB: Temporary stent placement with concurrent chemoradiation therapy in patients with unresectable oesophageal carcinoma: Is there an optimal time for stent removal? Eur Radiol. 23:1940–1945. 2013. View Article : Google Scholar : PubMed/NCBI

10 

Liu J, Shang L, Liu JY and Qin CY: Newly designed ‘pieced’ stent in a rabbit model of benign esophageal stricture. World J Gastroenterol. 21:8629–8635. 2015. View Article : Google Scholar : PubMed/NCBI

11 

Liu J, Shang L, Liu J and Qin C: A novel biodegradable esophageal stent: Results from mechanical and animal experiments. Am J Transl Res. 8:1108–1114. 2016.PubMed/NCBI

12 

Thompson JN: Corrosive esophageal injuries. II. An investigation of treatment methods and histochemical analysis of esophageal strictures in a new animal model. Laryngoscope. 97:1191–1202. 1987. View Article : Google Scholar : PubMed/NCBI

13 

Kozarek RA: Expandable endoprostheses for gastrointestinal stenoses. Gastrointest Endosc Clin North Am. 4:279–295. 1994. View Article : Google Scholar

14 

Tan BS, Kennedy C, Morgan R, Owen W and Adam A: Using uncovered metallic endoprostheses to treat recurrent benign esophageal strictures. AJR Am J Roentgenol. 169:1281–1284. 1997. View Article : Google Scholar : PubMed/NCBI

15 

Kim JH, Song HY, Choi EK, Kim KR, Shin JH and Lim JO: Temporary metallic stent placement in the treatment of refractory benign esophageal strictures: Results and factors associated with outcome in 55 patients. Eur Radiol. 19:384–390. 2009. View Article : Google Scholar : PubMed/NCBI

16 

Senousy BE, Gupte AR, Draganov PV, Forsmark CE and Wagh MS: Fully covered Alimaxx esophageal metal stents in the endoscopic treatment of benign esophageal diseases. Dig Dis Sci. 55:3399–3403. 2010. View Article : Google Scholar : PubMed/NCBI

17 

EI Hajj II, Imperiale TF, Rex DK, Ballard D, Kesler KA, Birdas TJ, Fatima H, Kessler WR and DeWitt JM: Treatment of esophageal leaks, fistulae, and perforations with temporary stents: Evaluation of efficacy, adverse events, and factors associated with successful outcomes. Gastrointest Endosc. 79:589–598. 2014. View Article : Google Scholar : PubMed/NCBI

18 

Wilson JL, Louie BE, Farivar AS, Vallières E and Aye RW: Fully covered self-expanding metal stents are effective for benign esophagogatric disruptions and strictures. J Gastrointest Surg. 17:2045–2050. 2013. View Article : Google Scholar : PubMed/NCBI

19 

Dua KS, Vleggaar FP, Santharam R and Siersema PD: Removable self-expanding plastic esophageal stent as a continuous, non-permanent dilator in treating refractory benign esophageal strictures: A prospective two-center study. Am J Gastroenterol. 103:2988–2994. 2008. View Article : Google Scholar : PubMed/NCBI

20 

Oh YS, Kochman ML, Ahmad NA and Ginsberg GG: Clinical outcomes after self-expanding plastic stent placement for refractory benign esophageal strictures. Dig Dis Sci. 55:1344–1348. 2010. View Article : Google Scholar : PubMed/NCBI

21 

Repici A, Conio M, De Angelis C, Battaglia E, Musso A, Pellicano R, Goss M, Venezia G, Rizzetto M and Saracco G: Temporary placement of an expandable polyester silicone-covered stent for treatmet of refractory benign esophageal stricture. Gastrointest Endosc. 60:513–519. 2004. View Article : Google Scholar : PubMed/NCBI

22 

Triester SL, Fleischer DE and Sharma VK: Failure of self-expanding plastic stents in treatment of refractory benign esopohageal strictures. Endoscopy. 38:533–537. 2006. View Article : Google Scholar : PubMed/NCBI

23 

Barthel JS, Kelley ST and Klapman JB: Management of persistent gastroesophageal anastomotic strictures with removalbe self-expandable polyester silicon-covered(Pollyflex) stents: An alternative to serial dilation. Gastrointest Endosc. 67:546–552. 2008. View Article : Google Scholar : PubMed/NCBI

24 

Saito Y, Tanaka T, Andoh A, Minematsu H, Hata K, Tsujikawa T, Nitta N, Murata K and Fujiyama Y: Novel biodegradable stents for benign esophageal strictures following endoscopic submucosal dissection. Dig Dis Sci. 53:330–333. 2008. View Article : Google Scholar : PubMed/NCBI

25 

van Boeckel PG, Vleggaar FP and Siersema PD: Biodegradable stent placement in the esophagus. Expert Rev Med Devices. 10:37–43. 2013. View Article : Google Scholar : PubMed/NCBI

26 

Dumoulin FL and Plassmann D: Tissue hyperplasia following placement of biodegradable stent for a refractory esophageal stricture: Treatment with argon plasm coagulation. Endoscopy. 44 (Suppl 2) UCTN:E356–E357. 2012. View Article : Google Scholar : PubMed/NCBI

27 

Hair CS and Devonshire DA: Severe hyperplastic tissue stenosis of a novel biodegradable esophageal stent and subsequent successful management with high-pressure balloon dilation. Endoscopy. 42 (Suppl 2):E132–E133. 2010. View Article : Google Scholar : PubMed/NCBI

28 

van Hooft JE, van Berge Henegouwen MI, Rauws EA, Bergman JJ, Busch OR and Fockens P: Endoscopic treatment of benign anastomotic esophagogastric strictures with a biodegradable stent. Gastrointest Endosc. 73:1043–1047. 2011. View Article : Google Scholar : PubMed/NCBI

29 

van Boeckel PG, Vleggaar FP and Siersema PD: A comparison of temporary self-expanding plastic and biodegradable stents for refractory benign esophageal strictures. Clin Gastroenterol Heppatol. 9:653–659. 2011. View Article : Google Scholar

30 

Tanaka T, Takahashi M, Nitta N, Furukawa A, Andoh A, Saito Y, Fujiyama Y and Murata K: Newly developed biodegradable stents for benign gastrointestinal tract stenoses: A preliminary clinical trial. Digestion. 74:199–205. 2006. View Article : Google Scholar : PubMed/NCBI

31 

Eloubeidi MA and Lopes TL: Novel removable internally fully covered self-expanding metal esophageal stent: Feasibility, technique of removal, and tissue response in humans. Am J Gastroenterol. 104:1374–1381. 2009. View Article : Google Scholar : PubMed/NCBI

32 

Hirdes MM, Siersema PH, Houben MH, Weusten BL and Vleggaar FP: Stent-in-stent technique for removal of embedded esophageal self-expanding metal stents. Am J Gastroenterol. 106:286–293. 2011. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Shang L, Pei QS, Xu D, Liu JY and Liu J: Novel detachable stents for the treatment of benign esophageal strictures. Exp Ther Med 19: 115-122, 2020.
APA
Shang, L., Pei, Q., Xu, D., Liu, J., & Liu, J. (2020). Novel detachable stents for the treatment of benign esophageal strictures. Experimental and Therapeutic Medicine, 19, 115-122. https://doi.org/10.3892/etm.2019.8190
MLA
Shang, L., Pei, Q., Xu, D., Liu, J., Liu, J."Novel detachable stents for the treatment of benign esophageal strictures". Experimental and Therapeutic Medicine 19.1 (2020): 115-122.
Chicago
Shang, L., Pei, Q., Xu, D., Liu, J., Liu, J."Novel detachable stents for the treatment of benign esophageal strictures". Experimental and Therapeutic Medicine 19, no. 1 (2020): 115-122. https://doi.org/10.3892/etm.2019.8190
Copy and paste a formatted citation
x
Spandidos Publications style
Shang L, Pei QS, Xu D, Liu JY and Liu J: Novel detachable stents for the treatment of benign esophageal strictures. Exp Ther Med 19: 115-122, 2020.
APA
Shang, L., Pei, Q., Xu, D., Liu, J., & Liu, J. (2020). Novel detachable stents for the treatment of benign esophageal strictures. Experimental and Therapeutic Medicine, 19, 115-122. https://doi.org/10.3892/etm.2019.8190
MLA
Shang, L., Pei, Q., Xu, D., Liu, J., Liu, J."Novel detachable stents for the treatment of benign esophageal strictures". Experimental and Therapeutic Medicine 19.1 (2020): 115-122.
Chicago
Shang, L., Pei, Q., Xu, D., Liu, J., Liu, J."Novel detachable stents for the treatment of benign esophageal strictures". Experimental and Therapeutic Medicine 19, no. 1 (2020): 115-122. https://doi.org/10.3892/etm.2019.8190
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