Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
January-2020 Volume 19 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2020 Volume 19 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion

  • Authors:
    • Guangyin Yu
    • Prince Last Mudenda Zilundu
    • Linlin Liu
    • Ke Zhong
    • Ying Tang
    • Zemin Ling
    • Li‑Hua Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Anatomy, Zhongshan School of Medicine, Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China, Department of Anatomy, School of Medicine, Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China
    Copyright: © Yu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 205-213
    |
    Published online on: November 18, 2019
       https://doi.org/10.3892/etm.2019.8209
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Estrogen‑related receptor γ (ERRγ) is a member of a small group of orphan nuclear receptor transcription factors that have been implicated in several physiological and pathological processes, including placental development, regulation of metabolic genes or disease. The pattern of expression of ERRγ, its role in neuronal injury and its co‑localization with other transcription factors in the spinal cord of rats with brachial plexus injury has not been determined. The expression profile of ERRγ and its co‑localization with RNA binding protein fox‑1 homolog 3 (NeuN) or cyclic AMP‑dependent transcription factor 3 (ATF‑3) in the motor neurons of rats that underwent brachial plexus root avulsion were assessed using western blot analysis, immunohistochemistry and immunofluorescence. Fluorogold (FG) was used to mark neurons whose axons were severed. ATF‑3 was expressed in the nuclei of motor neurons whose axons were severed by root avulsion. On day 3 post‑avulsion, FG and ATF‑3 were all co‑localized in the injured motor neurons. The level of ERRγ protein in the ipsilateral half of injured spinal cords was significantly decreased compared with that in the contralateral half on days 3, 14 and 28 post‑avulsion (all P<0.05). The numbers of ERRγ‑positive motor neurons (ERRγon) were also notably decreased in the ipsilateral side compared with that in the contralateral side on days 14 and 28 post‑avulsion, implying that the expression occurred in α motor neurons that were progressively being lost, a phenomenon that was expected post‑brachial plexus avulsion. Almost all large and small ERRγ‑positive motor neurons were also NeuN‑positive (NeuNon). However, a few of these were ERRγon/NeuNoff (no NeuN signal). Therefore, these results suggested that ERRγ is a non‑specific marker of γ motor neurons in rats, and therefore, this specific transcriptional program cannot be used to define functionally distinct motor neuron sub‑populations. However, its downregulation on the injured side suggests that it is an important component of the response to injury in motor neurons.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Lu Y, Liu H, Hua X, Xu WD, Xu JG and Gu YD: Supplementary motor cortical changes explored by resting-state functional connectivity in brachial plexus injury. World Neurosurg. 88:300–305. 2016. View Article : Google Scholar : PubMed/NCBI

2 

Noristani HN, Sabourin JC, Boukhaddaoui H, Chan-Seng E, Gerber YN and Perrin FE: Spinal cord injury induces astroglial conversion towards neuronal lineage. Mol Neurodeger. 11:68–81. 2016. View Article : Google Scholar

3 

Stifani N: Motor neurons and the generation of spinal motor neuron diversity. Front Cell Neurosci. 8:293–302. 2014. View Article : Google Scholar : PubMed/NCBI

4 

Manuel M and Zytnicki D: Alpha, beta and gamma motoneurons: Functional diversity in the motor system's final pathway. J Integr Neurosci. 10:243–276. 2011. View Article : Google Scholar : PubMed/NCBI

5 

Friese A, Kaltschmidt JA, Ladle DR, Sigrist M, Jessell TM and Arber S: Gamma and alpha motor neurons distinguished by expression of transcription factor ERR3. Proc Natl Acad Sci USA. 106:13588–13593. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Tremblay AM and Giguère V: The NR3B subgroup: An overview. Nucl Recept Signal. 5:e0092009.

7 

Giguère V: Transcriptional control of energy homeostasis by the estrogen related receptors. Endocr Rev. 29:677–696. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Deblois G and Giguère V: Functional and physiological genomics of estrogenrelated receptors (ERRs) in health and disease. Biochim Biophys Acta. 1812:1032–1040. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Huss JM, Garbacz WG and Xie W: Constitutive activities of estrogen-related receptors: Transcriptional regulation of metabolism by the ERR pathways in health and disease. Biochim Biophys Acta. 1852:1912–1927. 2015. View Article : Google Scholar : PubMed/NCBI

10 

He H, Xi G and Lu X: Molecular cloning, characterization, and expression analysis of an estrogen receptor-related receptor homologue in the cricket, Teleogryllus emma. J Insect Sci. 10:188–196. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Yoshihara E, Wei Z, Lin CS, Fang S, Ahmadian M, Kida Y, Tseng T, Dai Y, Yu RT, Liddle C, et al: ERRγ is required for the metabolic maturation of therapeutically functional glucose-responsive β cells. Cell Metab. 23:622–634. 2016. View Article : Google Scholar : PubMed/NCBI

12 

Deblois G and Giguère V: Oestrogen-related receptors in breast cancer: Control of cellular metabolism and beyond. Nat Rev Cancer. 13:27–36. 2013. View Article : Google Scholar : PubMed/NCBI

13 

Audet-Walsh É and Giguère V: The multiple universes of estrogen-related receptor alpha and gamma in metabolic control and related diseases. Acta Pharmacol Sin. 36:51–61. 2015. View Article : Google Scholar : PubMed/NCBI

14 

Luo J, Sladek R, Bader JA, Matthyssen A, Rossant J and Giguère V: Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-β. Nature. 388:778–782. 1997. View Article : Google Scholar : PubMed/NCBI

15 

Bonnelye E, Vanacker JM, Spruyt N, Alric S, Fournier B, Desbiens X and Laudet V: Expression of the estrogen-related receptor 1 (ERR-1) orphan receptor during mouse development. Mech Dev. 65:71–85. 1997. View Article : Google Scholar : PubMed/NCBI

16 

Hu JZ, Long H, Wu TD, Zhou Y and Lu HB: The effect of estrogen-related receptor α on the regulation of angiogenesis after spinal cord injury. Neuroscience. 290:570–580. 2015. View Article : Google Scholar : PubMed/NCBI

17 

Dufour CR, Wilson BJ, Huss JM, Kelly DP, Alaynick WA, Downes M, Evans RM, Blanchette M and Giguere V: Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRα and γ. Cell Metab. 5:345–356. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Kwon DH, Eom GH, Kee HJ, Nam YS, Cho YK, Kim DK, Koo JY, Kim HS, Nam KI, Kim KK, et al: Estrogen-related receptor gamma induces cardiac hypertrophy by activating GATA4. J Mol Cell Cardiol. 65:88–97. 2013. View Article : Google Scholar : PubMed/NCBI

19 

Murray J, Auwerx J and Huss JM: Impaired myogenesis in estrogen-related receptor γ (ERRγ)-deficient skeletal myocytes due to oxidative stress. FASEB J. 27:135–150. 2013. View Article : Google Scholar : PubMed/NCBI

20 

Pei L, Mu Y, Leblanc M, Alaynick W, Barish GD, Pankratz M, Tseng TW, Kaufman S, Liddle C, Yu RT, et al: Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism. Cell Metab. 21:628–636. 2015. View Article : Google Scholar : PubMed/NCBI

21 

Kida YS, Kawamura T, Wei Z, Sogo T, Jacinto S, Shigeno A, Kushige H, Yoshihara E, Liddle C, Ecker JR, et al: ERRs mediate a metabolic switch required for somatic cell reprogramming to pluripotency. Cell Stem Cell. 16:547–555. 2015. View Article : Google Scholar : PubMed/NCBI

22 

Mattson MP, Gleichmann M and Cheng A: Mitochondria in neuroplasticity and neurological disorders. Neuron. 60:748–766. 2008. View Article : Google Scholar : PubMed/NCBI

23 

Fleming JC, Norenberg MD, Ramsay DA, Dekaban GA, Marcillo AE, Saenz AD, Pasquale-Styles M, Dietrich WD and Weaver LC: The cellular inflammatory response in human spinal cords after injury. Brain. 129:3249–3269. 2006. View Article : Google Scholar : PubMed/NCBI

24 

Zhou LH, Han S, Xie YY, Wang LL and Yao ZB: Differences in c-jun and nNOS expression levels in motoneurons following different kinds of axonal injury in adult rats. Brain Cell Biol. 36:213–227. 2008. View Article : Google Scholar : PubMed/NCBI

25 

Wu W, Liuzzi FJ, Schinco FP, Depto AS, Li Y, Mong JA, Dawson TM and Snyder SH: Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury. Neurosci. 61:719–726. 1994. View Article : Google Scholar

26 

Fu R, Tang Y, Ling ZM, Li YQ, Cheng X, Song FH, Zhou LH and Wu W: Lithium enhances survival and regrowth of spinal motoneurons after ventral root avulsion. BMC Neurosci. 15:84–91. 2014. View Article : Google Scholar : PubMed/NCBI

27 

Tang Y, Ling ZM, Fu R, Li YQ, Cheng X, Song FH, Luo HX and Zhou LH: Time-specific microRNA changes during spinal motoneuron degeneration in adult rats following unilateral BPRA: Ipsilateral vs. contralateral changes. BMC Neurosci. 15:92–102. 2014. View Article : Google Scholar : PubMed/NCBI

28 

Wang J, Yan L, Zhao X, Wu W and Zhou LH: The diversity of nNOS gene expression in avulsion-injured spinal motoneurons among laboratory rodents. Nitric Oxide. 22:37–42. 2010. View Article : Google Scholar : PubMed/NCBI

29 

Zhou L and Wu W: Antisense oligos to neuronal nitric oxide synthase aggravate motoneuron death induced by spinal root avulsion in the adult rat. Exp Neurol. 197:84–92. 2006. View Article : Google Scholar : PubMed/NCBI

30 

Li YQ, Tang Y, Fu R, Meng QH, Zhou X, Ling ZM, Cheng X, Tian SW, Wang GJ, Liu XG and Zhou LH: Efficient labeling in vitro with non-ionic gadolinium magnetic resonance imaging contrast agent and fluorescent transfection agent in bone marrow stromal cells of neonatal rats. Mol Med Rep. 12:913–920. 2015. View Article : Google Scholar : PubMed/NCBI

31 

Linda H, Skold MK and Ochsmann T: Activating transcription factor 3, a useful marker for a regenerative response after nerve root injury. Front Neurol. 2:30–38. 2011. View Article : Google Scholar : PubMed/NCBI

32 

Chen BP, Wolfgang CD and Hai T: Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10. Mol Cell Biol. 16:1157–1168. 1996. View Article : Google Scholar : PubMed/NCBI

33 

Yin T, Sandhu G, Wolfgang CD, Burrier A, Webb RL, Rigel DF, Hai T and Whelan J: Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney. J Biol Chem. 272:19943–19950. 1997. View Article : Google Scholar : PubMed/NCBI

34 

Powis RA and Gillingwater TH: Selective loss of alpha motor neurons with sparing of gamma motor neurons and spinal cord cholinergic neurons in a mouse model of spinal muscular atrophy. J Anat. 228:443–451. 2016. View Article : Google Scholar : PubMed/NCBI

35 

Lalancette-Hebert M, Sharma A, Lyashchenko AK and Shneider NA: Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS. Proc Natl Acad Sci USA. 113:E8316–E8325. 2016. View Article : Google Scholar : PubMed/NCBI

36 

Martín MC, Balfagón G, Minoves N and Blanco J: Androgen deprivation increases neuronal nitric oxide metabolism and its vasodilator effect in rat mesenteric arteries. Nitric Oxide. 12:163–176. 2005. View Article : Google Scholar : PubMed/NCBI

37 

Raivich G, Bohatschek M, Da Costa C, Iwata O, Galiano M, Hristova M, Nateri AS, Makwana M, Riera-Sans L, Wolfer DP, et al: The AP-1 transcription factor c-jun is required for efficient axonal regeneration. Neuron. 43:57–67. 2004. View Article : Google Scholar : PubMed/NCBI

38 

Giguère V, Yang N, Segui P and Evans RM: Identification of a new class of steroid hormone receptors. Nature. 331:91–94. 1988. View Article : Google Scholar : PubMed/NCBI

39 

Hong H, Yang L and Stallcup: MR Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3. J Biol Chem. 274:22618–22626. 1999. View Article : Google Scholar : PubMed/NCBI

40 

Zhang Z and Teng CT: Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression. Mol Cell Endocrinol. 264:128–141. 2006. View Article : Google Scholar : PubMed/NCBI

41 

Sladek R, Bader JA and Giguère V: The orphan nuclear receptor estrogenrelated receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Mol Cell Biol. 17:5400–5409. 1997. View Article : Google Scholar : PubMed/NCBI

42 

Cao J and Patisaul HB: Sexually dimorphic expression of hypothalamic estrogen receptors α and β and Kiss1 in neonatal male and female rats. J Comp Neurol. 519:2954–2977. 2011. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Yu G, Zilundu PL, Liu L, Zhong K, Tang Y, Ling Z and Zhou LH: ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion. Exp Ther Med 19: 205-213, 2020.
APA
Yu, G., Zilundu, P.L., Liu, L., Zhong, K., Tang, Y., Ling, Z., & Zhou, L. (2020). ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion. Experimental and Therapeutic Medicine, 19, 205-213. https://doi.org/10.3892/etm.2019.8209
MLA
Yu, G., Zilundu, P. L., Liu, L., Zhong, K., Tang, Y., Ling, Z., Zhou, L."ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion". Experimental and Therapeutic Medicine 19.1 (2020): 205-213.
Chicago
Yu, G., Zilundu, P. L., Liu, L., Zhong, K., Tang, Y., Ling, Z., Zhou, L."ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion". Experimental and Therapeutic Medicine 19, no. 1 (2020): 205-213. https://doi.org/10.3892/etm.2019.8209
Copy and paste a formatted citation
x
Spandidos Publications style
Yu G, Zilundu PL, Liu L, Zhong K, Tang Y, Ling Z and Zhou LH: ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion. Exp Ther Med 19: 205-213, 2020.
APA
Yu, G., Zilundu, P.L., Liu, L., Zhong, K., Tang, Y., Ling, Z., & Zhou, L. (2020). ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion. Experimental and Therapeutic Medicine, 19, 205-213. https://doi.org/10.3892/etm.2019.8209
MLA
Yu, G., Zilundu, P. L., Liu, L., Zhong, K., Tang, Y., Ling, Z., Zhou, L."ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion". Experimental and Therapeutic Medicine 19.1 (2020): 205-213.
Chicago
Yu, G., Zilundu, P. L., Liu, L., Zhong, K., Tang, Y., Ling, Z., Zhou, L."ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion". Experimental and Therapeutic Medicine 19, no. 1 (2020): 205-213. https://doi.org/10.3892/etm.2019.8209
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team