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Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial

  • Authors:
    • Wei Wei
    • Wenya Bai
    • Yanchao Yang
    • Yang Li
    • Xiufei Teng
    • Yuxiao Wan
    • Junchao Zhu
  • View Affiliations / Copyright

    Affiliations: Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China
    Copyright: © Wei et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 511-518
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    Published online on: November 26, 2019
       https://doi.org/10.3892/etm.2019.8245
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Abstract

Laparoscopy is performed worldwide due to its limited side effects and optimal treatment efficacy. However, it also has adverse effects, including atelectasis and ischemia‑reperfusion injury, due to CO2 accumulation during ventilation in a head‑down position, which may result in severe disorders and adversely affecting postoperative recovery, prolonging hospitalization. The present study was performed to assess whether transcutaneous electrical acupoint stimulation (TEAS) protects against lung injury occurring during gynecological laparoscopic surgery. Patients were randomly allocated to two groups: Control group (received no stimulation) and TEAS group (patients treated with TEAS on BL13, LI4 and LU5). The mean arterial pressure, heart rate and oxygen saturation were recorded at the time‑points of arriving in the operating room (T0), immediately prior to induction of the pneumoperitoneum (T1), immediately after the end of pneumoperitoneum (T2) and on leaving the operating room (T3). Arterial blood gas analysis was performed to record the pH, determine the partial pressure of carbon dioxide and calculate the oxygenation index (OI) at T0‑3. Blood samples were taken from the peripheral vein for determination of the serum concentrations of tumor necrosis factor (TNF)‑α and interleukin (IL)‑1β at T0 and T3. Post‑operative pulmonary complications occurring during the first five days after surgery were also recorded. A total of 100 patients were initially enrolled and 80 patients were analysed. The results indicated that the OI in the control group was significantly lower than that in the TEAS group at the T2 and T3 time‑points. The serum concentrations of TNF‑α and IL‑1β were significantly increased following surgery, while the extent of these increases was lower in the TEAS group compared with that in the control group. The incidence of post‑operative pulmonary complications was significantly lower in the TEAS group. It was therefore indicated that TEAS protect against lung injury as a complication of gynecological laparoscopic surgery. The present study was registered at http://www.clinicaltrials.gov prior to enrollment of the patients (no. NCT02850471).
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Copy and paste a formatted citation
Spandidos Publications style
Wei W, Bai W, Yang Y, Li Y, Teng X, Wan Y and Zhu J: Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial. Exp Ther Med 19: 511-518, 2020.
APA
Wei, W., Bai, W., Yang, Y., Li, Y., Teng, X., Wan, Y., & Zhu, J. (2020). Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial. Experimental and Therapeutic Medicine, 19, 511-518. https://doi.org/10.3892/etm.2019.8245
MLA
Wei, W., Bai, W., Yang, Y., Li, Y., Teng, X., Wan, Y., Zhu, J."Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial". Experimental and Therapeutic Medicine 19.1 (2020): 511-518.
Chicago
Wei, W., Bai, W., Yang, Y., Li, Y., Teng, X., Wan, Y., Zhu, J."Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial". Experimental and Therapeutic Medicine 19, no. 1 (2020): 511-518. https://doi.org/10.3892/etm.2019.8245
Copy and paste a formatted citation
x
Spandidos Publications style
Wei W, Bai W, Yang Y, Li Y, Teng X, Wan Y and Zhu J: Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial. Exp Ther Med 19: 511-518, 2020.
APA
Wei, W., Bai, W., Yang, Y., Li, Y., Teng, X., Wan, Y., & Zhu, J. (2020). Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial. Experimental and Therapeutic Medicine, 19, 511-518. https://doi.org/10.3892/etm.2019.8245
MLA
Wei, W., Bai, W., Yang, Y., Li, Y., Teng, X., Wan, Y., Zhu, J."Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial". Experimental and Therapeutic Medicine 19.1 (2020): 511-518.
Chicago
Wei, W., Bai, W., Yang, Y., Li, Y., Teng, X., Wan, Y., Zhu, J."Pulmonary protection of transcutaneous electrical acupoint stimulation in gynecological laparoscopic surgery: A randomized controlled trial". Experimental and Therapeutic Medicine 19, no. 1 (2020): 511-518. https://doi.org/10.3892/etm.2019.8245
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