A novel approach regarding the anti‑aging of facial skin through collagen reorganization

Sifaki,Maria; Calina,Daniela; Docea,Anca   Oana; Tsioumas,Sotiris; Katsarou,Martha‑Spyridoula; Papadogiorgaki,Sevasti; Fragkiadaki,Persefoni; Branisteanu,Daciana   Elena; Kouskoukis,Konstantinos; Tsiaoussis,John; Spandidos,Demetrios   A.

doi:10.3892/etm.2019.8254

January-2020 Volume 19 Issue 1

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January-2020 Volume 19 Issue 1

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Article Open Access

A novel approach regarding the anti‑aging of facial skin through collagen reorganization

Authors:
- Maria Sifaki
- Daniela Calina
- Anca Oana Docea
- Sotiris Tsioumas
- Martha‑Spyridoula Katsarou
- Sevasti Papadogiorgaki
- Persefoni Fragkiadaki
- Daciana Elena Branisteanu
- Konstantinos Kouskoukis
- John Tsiaoussis
- Demetrios A. Spandidos
View Affiliations / Copyright

Affiliations: Private Practice Dermatologist‑Venereologist, 71305 Heraklion, Greece, Department of Clinical Pharmacy, Dermatopharmacy and Cosmetology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania, Department of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania, Private Practice Ophthalmologist, 11528 Athens, Greece, Research Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15772 Athens, Greece, Teaching and Technical Support Staff, Laboratory of Electron Microscope, Medical School, University of Crete, 71003 Heraklion, Greece, Laboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece, Department of Dermatology, University of Medicine and Pharmacy ‘Gr. T. Popa’, 700115 Iasi, Romania, Department of Dermatology and Venereology, Medical School, Democritus University of Thrace, 68100 Alexandroupoli, Greece, Laboratory of Anatomy‑Histology‑Embryology, Medical School, University of Crete, 71003 Heraklion, Greece, Laboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece

Copyright: © Sifaki et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 717-721
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Published online on: November 27, 2019

https://doi.org/10.3892/etm.2019.8254
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Abstract

The needle shaping technique can be used to perform subcutaneous microtransplants, enabling the ‘lifting’ of the skin. This prospective cohort study aimed to examine the effects of needle shaping on facial skin tone, volume and histological structure. A total of 54 women underwent the needle shaping procedure performed by inserting a tiny acupuncture needle combined with mixed electrical currents. The overall treatment was completed within 4 sessions of 2 months apart, once every 15 days. Maintenance was ensured by 2 sessions (no longer than 15 days apart) every 6 months. Macroscopic skin appearance was evaluated by a specialized dermatologist and the satisfaction of the patients was assessed. The microscopic structure of the skin dermis was evaluated by optic and scanning electron microscopy. I‑chrome staining demonstrated more compact dermis‑collagen fibers which were larger and thicker as compared to the controls. Scanning electron microscopy demonstrated an increased dermis thickness as compared to pre‑treatment. All patients that answered to the follow up reported satisfaction during assessment. The satisfaction of the patients was very good and excellent in 45% of cases. The results of the needle‑shaping procedure are natural with no scaring or down time. Moreover, the result is lasting even for 1 year, depending always on the subject's lifestyle and general health condition.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

A novel approach regarding the anti‑aging of facial skin through collagen reorganization

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