Beneficial effects of food supplements based on hydrolyzed collagen for skin care (Review)
- Mihaela‑Adi Lupu
- Gratiela Gradisteanu Pircalabioru
- Mariana‑Carmen Chifiriuc
- Radu Albulescu
- Cristiana Tanase
Affiliations: SC Sanimed International Impex SRL, 087040 Bucharest, Romania, Research Institute of University of Bucharest (ICUB), 050098 Bucharest, Romania, Biochemistry‑Proteomics Department, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania
- Published online on: December 17, 2019 https://doi.org/10.3892/etm.2019.8342
Copyright: © Lupu
et al. This is an open access article distributed under the
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Commons Attribution License.
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Ageing is a complex, multi‑step process which involves, among others loss of collagen and elastin. Collagen is found in large amounts in the body, especially in the dermis layer. These fibers provide the skin's normal strength, hydration and mechanical properties. Collagen is largely available, as it can be extracted from many animal sources, it can be easily absorbed upon topical administration, hence it is largely used in the cosmetic and pharmaceutical industry for the treatment of premature aging. Bioactive peptides, such as collagen hydrolyzate, are among the most used ingredients for the development of nutraceuticals ‑ food or food ingredients that have defined physiological effects. Numerous studies have demonstrated that peptides resulted from ingestion of hydrolysate collagen and detected in the blood stream have chemotactic properties for skin fibroblasts, helping the skin restoration process. The purpose of this minireview is to present an update on the use of hydrolyzed collagen for skin care.