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Article

Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension

  • Authors:
    • Xiurong Sun
    • Fangming Su
    • Xuelin Chen
    • Qihui Peng
    • Xiaomin Luo
    • Xinghai Hao
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, P.R. China, Department of Ultrasonography, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, P.R. China, Department of Healthcare, Beijing Genomics Institute, Shenzhen, Guangdong 518083, P.R. China, Department of Cardiac Surgery, Beijing Anzhen Hospital, Beijing 100029, P.R. China
  • Pages: 1955-1960
    |
    Published online on: December 31, 2019
       https://doi.org/10.3892/etm.2019.8405
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Abstract

The current study investigated whether placentation and systemic inflammation are associated with pregnancy‑induced hypertension (PIH) or pre‑eclampsia (PE), and evaluated some measurable indexes for assessment of maternal factors contributing to high‑risk pregnancy. Photoplethysmographic reflection index (PPG RI), uterine artery (UtA) pulsatile index (PI) and reflection index (RI), as well as maternal serum placental growth factor (PlGF) and soluble endoglin (sEng) were measured in pregnant women with singleton pregnancy at the gestational age of 22 to 23 weeks. Study subjects were women with normal pregnancy (NP, n=24), PIH (n=14) and PE (n=16). It was found that individuals in the PIH group exhibited higher UtA RI and UtA PI values, as well as PPG RI values compared with individuals in the NP group. Individuals in the PE group had the highest UtA RI, UtA PI and PPG RI values among these 3 groups. UtA and PPG results were significantly different in PIH and PE groups compared with the NP group. Significant differences were found in both PlGF and sEng levels between PIH and PE groups. A strong inverse across‑subject correlation was found between PlGF and sEng levels. A weak inverse correlation was found between PlGF and UtA RI, and PlGF and UtA PI. A moderate inverse correlation was found between PlGF and PPG RI. A moderate positive correlation was found between either sEng and UtA RI or sEng and UtA PI. A very strong positive correlation was found between sEng and PPG RI. Taken together, the current results indicated that maternal effects related to cardiovascular adaptation to placentation and systemic inflammation exhibited significant differences between NP and PIH or PE groups. Therefore, assessment of UtA and PPG could be used for identifying high‑risk pregnancy.
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Copy and paste a formatted citation
Spandidos Publications style
Sun X, Su F, Chen X, Peng Q, Luo X and Hao X: Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension. Exp Ther Med 19: 1955-1960, 2020.
APA
Sun, X., Su, F., Chen, X., Peng, Q., Luo, X., & Hao, X. (2020). Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension. Experimental and Therapeutic Medicine, 19, 1955-1960. https://doi.org/10.3892/etm.2019.8405
MLA
Sun, X., Su, F., Chen, X., Peng, Q., Luo, X., Hao, X."Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension". Experimental and Therapeutic Medicine 19.3 (2020): 1955-1960.
Chicago
Sun, X., Su, F., Chen, X., Peng, Q., Luo, X., Hao, X."Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension". Experimental and Therapeutic Medicine 19, no. 3 (2020): 1955-1960. https://doi.org/10.3892/etm.2019.8405
Copy and paste a formatted citation
x
Spandidos Publications style
Sun X, Su F, Chen X, Peng Q, Luo X and Hao X: Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension. Exp Ther Med 19: 1955-1960, 2020.
APA
Sun, X., Su, F., Chen, X., Peng, Q., Luo, X., & Hao, X. (2020). Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension. Experimental and Therapeutic Medicine, 19, 1955-1960. https://doi.org/10.3892/etm.2019.8405
MLA
Sun, X., Su, F., Chen, X., Peng, Q., Luo, X., Hao, X."Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension". Experimental and Therapeutic Medicine 19.3 (2020): 1955-1960.
Chicago
Sun, X., Su, F., Chen, X., Peng, Q., Luo, X., Hao, X."Doppler ultrasound and photoplethysmographic assessment for identifying pregnancy‑induced hypertension". Experimental and Therapeutic Medicine 19, no. 3 (2020): 1955-1960. https://doi.org/10.3892/etm.2019.8405
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