|
1
|
Global Initiative for Asthma (GINA):
Global Strategy for Asthma Management and Prevention. GINA, 2019.
http://www.ginasthma.org
|
|
2
|
Bergmann KC: Bronchial asthma-many types,
different therapies. Dtsch Med Wochenschr. 141:687–692.
2016.PubMed/NCBI
|
|
3
|
Deng Y, Chen W, Zang N, Li S, Luo Y, Ni K,
Wang L, Xie X, Liu W, Yang X, et al: The antiasthma effect of
neonatal BCG vaccination does not depend on the Th17/Th1 but
IL-17/IFN-γ balance in a BALB/c mouse asthma model. J Clin Immunol.
31:419–429. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Agarwal A, Singh M, Chatterjee BP, Chauhan
A and Chakraborti A: Interplay of T Helper 17 cells with
CD4(+)CD25(high) FOXP3(+) tregs in regulation of allergic asthma in
pediatric patients. Int J Pediatr. 2014:6362382014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kim HJ, Lee HJ, Jeong SJ, Lee HJ, Kim SH
and Park EJ: Cortex Mori Radicis extract exerts antiasthmatic
effects via enhancement of CD4(+)CD25(+)Foxp3(+) regulatory T cells
and inhibition of Th2 cytokines in a mouse asthma model. J
Ethnopharmacol. 138:40–46. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Swamy RS, Reshamwala N, Hunter T,
Vissamsetti S, Santos CB, Baroody FM, Hwang PH, Hoyte EG, Garcia MA
and Nadeau KC: Epigenetic modifications and improved regulatory
T-cell function in subjects undergoing dual sublingual
immunotherapy. J Allergy Clin Immunol. 130:215–224.e7. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yeh H, Moore DJ, Markmann JF and Kim JI:
Mechanisms of regulatory T cell counter-regulation by innate
immunity. Transplant Rev (Orlando). 27:61–64. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Janson PC, Winerdal ME, Marits P, Thorn M,
Ohlsson R and Winqvist O: FOXP3 promoter demethylation reveals the
committed Treg population in humans. PLoS One. 3:e16122008.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Walker LS: Treg and CTLA-4: Two
intertwining pathways to immune tolerance. J Autoimmun. 45:49–57.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Khan U and Ghazanfar H: T Lymphocytes and
Autoimmunity. Int Rev Cell Mol Biol. 341:125–168. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ray A, Khare A, Krishnamoorthy N, Qi Z and
Ray P: Regulatory T cells in many flavors control asthma. Mucosal
Immunol. 3:216–229. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Sakaguchi S, Yamaguchi T, Nomura T and Ono
M: Regulatory T cells and immune tolerance. Cell. 133:775–787.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Beyer M and Schultze JL: Plasticity of
T(reg) cells: Is reprogramming of T(reg) cells possible in the
presence of FOXP3? Int Immunopharmacol. 11:555–560. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kuo CH, Hsieh CC, Lee MS, Chang KT, Kuo HF
and Hung CH: Epigenetic regulation in allergic diseases and related
studies. Asia Pac Allergy. 4:14–18. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Morikawa H and Sakaguchi S: Genetic and
epigenetic basis of Treg cell development and function: From a
FoxP3-centered view to an epigenome-defined view of natural Treg
cells. Immunol Rev. 259:192–205. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Liu Y, Peng B, Wu S and Xu N: Epigenetic
regulation of regulatory T cells in Kidney disease and
transplantation. Curr Gene Ther. 17:461–468. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Wieczorek G, Asemissen A, Model F,
Turbachova I, Floess S, Liebenberg V, Baron U, Stauch D, Kotsch K,
Pratschke J, et al: Quantitative DNA methylation analysis of FOXP3
as a new method for counting regulatory T cells in peripheral blood
and solid tissue. Cancer Res. 69:599–608. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Yang J, Yuan X, Lv C, Bai R, Zhang L,
Ruang L, Zhang C and Quan XQ: Methylation of the FOXP3 upstream
enhancer as a clinical indicator of defective regulatory T cells in
patients with acute coronary syndrome. Am J Transl Res.
8:5298–5308. 2016.PubMed/NCBI
|
|
19
|
CMA RG: Guidelines for diagnosis and
prevention of bronchial Asthma in Children. Chin J Pediat.
54:167–181. 2016.
|
|
20
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Nishimoto T and Kuwana M: CD4+CD25+Foxp3+
regulatory T cells in the pathophysiology of immune
thrombocytopenia. Semin Hematol. 50 (Suppl):S43–S49. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Spreafico R, Rossetti M, van den Broek T,
Jansen NJ, Zhang H, Moshref M, Prakken B, van Loosdregt J, van Wijk
F and Albani S: A sensitive protocol for FOXP3 epigenetic analysis
in scarce human samples. Eur J Immunol. 44:3141–3143. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Liang M, Liwen Z, Yun Z, Yanbo D and
Jianping C: The imbalance between Foxp3+Tregs and
Th1/Th17/Th22 cells in patients with Newly diagnosed autoimmune
hepatitis. J Immunol Res. 2018:37530812018. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Li Y, Fan XS, Yu JH, Xu L and Wang SS:
CD4+CD25+FOXP3+ T cells, Foxp3
gene and protein expression contribute to antiasthmatic effects of
San'ao decoction in mice model of asthma. Phytomedicine.
21:656–662. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Paust S, Lu L, McCarty N and Cantor H:
Engagement of B7 on effector T cells by regulatory T cells prevents
autoimmune disease. Proc Natl Acad Sci USA. 101:10398–10403. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Prunicki M, Stell L, Dinakarpandian D, de
Planell-Saguer M, Lucas RW, Hammond SK, Balmes JR, Zhou X, Paglino
T, Sabatti C, et al: Exposure to NO2, CO, and
PM2.5 is linked to regional DNA methylation differences
in asthma. Clin Epigenetics. 10:22018. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Yang IV and Schwartz DA: Epigenetic
mechanisms and the development of asthma. J Allergy Clin Immunol.
130:1243–1255. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Marques CR, Costa RS, Costa GNO, da Silva
TM, Teixeira TO, de Andrade EMM, Galvão AA, Carneiro VL and
Figueiredo CA: Genetic and epigenetic studies of FOXP3 in asthma
and allergy. Asthma Res Pract. 1:102015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Provoost S, Maes T, van Durme YM, Gevaert
P, Bachert C, Schmidt-Weber CB, Brusselle GG, Joos GF and Tournoy
KG: Decreased FOXP3 protein expression in patients with asthma.
Allergy. 64:1539–1546. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Lu Y, Malmhall C, Sjöstrand M, Rådinger M,
O'Neil SE, Lötvall J and Bossios A: Expansion of CD4(+) CD25(+) and
CD25(−) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic
inflammation, local lung distribution and chemokine gene
expression. PLoS One. 6:e198892011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Suárez-Álvarez B, Baragaño Raneros A,
Ortega F and Lòpez-Larrea C: Epigenetic modulation of the immune
function: A potential target for tolerance. Epigenetics. 8:694–702.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wysocki K, Conley Y and Wenzel S:
Epigenome variation in severe asthma. Biol Res Nurs. 17:263–269.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Gaffin JM, Raby BA, Petty CR, Hoffman EB,
Baccarelli AA, Gold DR and Phipatanakul W: β-2 adrenergic receptor
gene methylation is associated with decreased asthma severity in
Inner-City Schoolchildren: Asthma and rhinitis. Clin Exp Allergy.
44:681–689. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Polansky JK, Schreiber L, Thelemann C,
Ludwig L, Krüger M, Baumgrass R, Cording S, Floess S, Hamann A and
Huehn J: Methylation matters: Binding of Ets-1 to the demethylated
Foxp3 gene contributes to the stabilization of Foxp3 expression in
regulatory T cells. J Mol Med (Berl). 88:1029–1040. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Zhao M, Liang GP, Tang MN, Luo SY, Zhang
J, Cheng WJ, Chan TM and Lu QJ: Total glucosides of paeony induces
regulatory CD4(+)CD25(+) T cells by increasing Foxp3 demethylation
in lupus CD4(+) T cells. Clin Immunol. 143:180–187. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Yang IV, Pedersen BS, Liu A, O'Connor GT,
Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler
SJ, et al: DNA methylation and childhood asthma in the inner city.
J Allergy Clin Immunol. 136:69–80. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Brunst KJ, Leung YK, Ryan PH, Khurana
Hershey GK, Levin L, Ji H, Lemasters GK and Ho SM: Forkhead box
protein 3 (FOXP3) hypermethylation is associated with diesel
exhaust exposure and risk for childhood asthma. J Allergy Clin
Immunol. 131:592–594.e1-3. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Nadeau K, McDonald-Hyman C, Noth EM, Pratt
B, Hammond SK, Balmes J and Tager I: Ambient air pollution impairs
regulatory T-cell function in asthma. J Allergy Clin Immunol.
126:845–852.e10. 2010. View Article : Google Scholar : PubMed/NCBI
|
