|
1
|
Bielack SS, Kempf-Bielack B, Delling G,
Exner GU, Flege S, Helmke K, Kotz R, Salzer-Kuntschik M, Werner M,
Winkelmann W, et al: Prognostic factors in high-grade osteosarcoma
of the extremities or trunk: An analysis of 1,702 patients treated
on neoadjuvant cooperative osteosarcoma study group protocols. J
Clin Oncol. 20:776–790. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Zhao H, Yao Y, Wang Z, Lin F, Sun Y and
Chen P: Therapeutic effect of pirarubicin-based chemotherapy for
osteosarcoma patients with lung metastasis. J Chemother.
22:119–124. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
He A, Yang X, Huang Y, Feng T, Wang Y, Sun
Y, Shen Z and Yao Y: CD133(+) CD44(+) cells mediate in the lung
metastasis of osteosarcoma. J Cell Biochem. 116:1719–1729. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Chen J, Ma L, Wei G; Comment on Fu, ; et
al: A systematic review of p53 as a biomarker of survival in
patients with osteosarcoma. Tumour Biol. 35:5049–5050. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Shin SH, Jeong HJ, Han I, Cho HS and Kim
HS: Osteosarcoma and chondrosarcoma of the shoulder: Site-specific
comparative analysis. Orthopedics. 36:e179–e185. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Turley H, Wykoff CC, Troup S, Watson PH,
Gatter KC and Harris AL: The hypoxia-regulated transcription factor
DEC1 (Stra13, SHARP-2) and its expression in human tissues and
tumours. J Pathol. 203:808–813. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kato Y, Kawamoto T, Fujimoto K and Noshiro
M: DEC1/STRA13/SHARP2 and DEC2/SHARP1 coordinate physiological
processes, including circadian rhythms in response to environmental
stimuli. Curr Top Dev Biol. 110:339–372. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Sato F, Bhawal UK, Yoshimura T and
Muragaki Y: DEC1 and DEC2 crosstalk between circadian rhythm and
tumor progression. J Cancer. 7:153–159. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Miyazaki K, Kawamoto T, Tanimoto K,
Nishiyama M, Honda H and Kato Y: Identification of functional
hypoxia response elements in the promoter region of the DEC1 and
DEC2 genes. J Boil Chem. 277:47014–47021. 2002. View Article : Google Scholar
|
|
10
|
Yamada K and Miyamoto K: Basic
helix-loop-helix transcription factors, BHLHB2 and BHLHB3; Their
gene expressions are regulated by multiple extracellular stimuli.
Front Biosci. 10:3151–3171. 2005. View
Article : Google Scholar : PubMed/NCBI
|
|
11
|
Marczak MM and Yan B: Circadian
rhythmicity: A functional connection between differentiated
embryonic chondrocyte-1 (DEC1) and small heterodimer partner (SHP).
Arch Biochem Biophys. 631:11–18. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Iwata T, Kawamoto T, Sasabe E, Miyazaki K,
Fujimoto K, Noshiro M, Kurihara H and Kato Y: Effects of
overexpression of basic helix-loop-helix transcription factor Dec1
on osteogenic and adipogenic differentiation of mesenchymal stem
cells. Eur J Cell Boil. 85:423–431. 2006. View Article : Google Scholar
|
|
13
|
Wu Y, Sato F, Yamada T, Bhawal UK,
Kawamoto T, Fujimoto K, Noshiro M, Seino H, Morohashi S, Hakamada
K, et al: The BHLH transcription factor DEC1 plays an important
role in the epithelial-mesenchymal transition of pancreatic cancer.
Int J Oncol. 41:1337–1346. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
You J, Lin L, Liu Q, Zhu T, Xia K and Su
T: The correlation between the expression of differentiated
embryo-chondrocyte expressed gene l and oral squamous cell
carcinoma. Eur J Med Res. 19:212014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Liu Y, Miao Y, Wang J, Lin X, Wang L, Xu
HT and Wang EH: DEC1 is positively associated with the malignant
phenotype of invasive breast cancers and negatively correlated with
the expression of claudin-1. Int J Mol Med. 31:855–860. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Xu Q, Ma P, Hu C, Chen L, Xue L, Wang Z,
Liu M, Zhu H, Xu N and Lu N: Overexpression of the DEC1 protein
induces senescence in vitro and is related to better survival in
esophageal squamous cell carcinoma. PLoS One. 7:e418622012.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Liu Y, Wang L, Lin XY, Wang J, Yu JH, Miao
Y and Wang EH: The transcription factor DEC1
(BHLHE40/STRA13/SHARP-2) is negatively associated with TNM stage in
non-small-cell lung cancer and inhibits the proliferation through
cyclin D1 in A549 and BE1 cells. Tumour Biol. 34:1641–1650. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Jia Y, Hu R, Li P, Zheng Y, Wang Y and Ma
X: DEC1 is required for anti-apoptotic activity of gastric cancer
cells under hypoxia by promoting Survivin expression. Gastric
Cancer. 21:632–642. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ma W, Shi X, Lu S, Wu L and Wang Y:
Hypoxia-induced overexpression of DEC1 is regulated by HIF-1α in
hepatocellular carcinoma. Oncol Rep. 30:2957–2962. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zheng Q, Wang C, Wang L, Zhang D, Liu N,
Ming X, Zhou H, Guli Q and Liu Y: Interaction with SP1, but not
binding to the E-box motifs, is responsible for
BHLHE40/DEC1-induced transcriptional suppression of CLDN1 and cell
invasion in MCF-7 cells. Mol Carcinog. 57:1116–1129. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhou L, Yu Y, Sun S, Zhang T and Wang M:
Cry 1 regulates the clock gene network and promotes proliferation
and migration via the akt/P53/P21 pathway in human osteosarcoma
cells. J Cancer. 9:2480–2491. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Jia YF, Xiao DJ, Ma XL, Song YY, Hu R,
Kong Y, Zheng Y, Han SY, Hong RL and Wang YS: Differentiated
embryonic chondrocyte-expressed gene 1 is associated with
hypoxia-inducible factor 1α and Ki67 in human gastric cancer. Diagn
Pathol. 8:372013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zheng Y, Jia Y, Wang Y, Wang M, Li B, Shi
X, Ma X, Xiao D and Sun Y: The hypoxia-regulated transcription
factor DEC1 (Stra13, SHARP-2) and its expression in gastric cancer.
OMICS. 13:301–306. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Shi XH, Zheng Y, Sun Q, Cui J, Liu QH, Qü
F and Wang YS: DEC1 nuclear expression: A marker of differentiation
grade in hepatocellular carcinoma. World J Gastroenterol.
17:2037–2043. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wang W, Reiser-Erkan C, Michalski CW,
Raggi MC, Quan L, Yupei Z, Friess H, Erkan M and Kleeff J: Hypoxia
inducible BHLHB2 is a novel and independent prognostic marker in
pancreatic ductal adenocarcinoma. Biochem Biophys Res Commun.
401:422–428. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Chakrabarti J, Turley H, Campo L, Han C,
Harris AL, Gatter KC and Fox SB: The transcription factor DEC1
(stra13, SHARP2) is associated with the hypoxic response and high
tumour grade in human breast cancers. Br J Cancer. 91:954–958.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Giatromanolaki A, Koukourakis MI, Sivridis
E, Turley H, Wykoff CC, Gatter KC and Harris AL: DEC1 (STRA13)
protein expression relates to hypoxia-inducible factor 1-alpha and
carbonic anhydrase-9 overexpression in non-small cell lung cancer.
J Pathol. 200:222–228. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Li Y, Xie M, Yang J, Yang D, Deng R, Wan Y
and Yan B: The expression of antiapoptotic protein survivin is
transcriptionally upregulated by DEC1 primarily through multiple
sp1 binding sites in the proximal promoter. Oncogene. 25:3296–3306.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Thin TH, Li L, Chung TK, Sun H and Taneja
R: Stra13 is induced by genotoxic stress and regulates
ionizing-radiation-induced apoptosis. EMBO Rep. 8:401–407. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Sgourakis G, Gockel I, Lyros O, Hansen T,
Mildenberger P and Lang H: Detection of lymph node metastases in
esophageal cancer. Expert Rev Anticancer Ther. 11:601–612. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Nieto MA, Huang RY, Jackson RA and Thiery
JP: EMT: 2016. Cell. 166:21–45. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Samant RS and Shevde LA: NMI and EMT.
Oncoscience. 1:476–477. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Turley EA, Veiseh M, Radisky DC and
Bissell MJ: Mechanisms of disease: Epithelial-mesenchymal
transition-does cellular plasticity fuel neoplastic progression?
Nat Clin Pract Oncol. 5:280–290. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Kon N, Hirota T, Kawamoto T, Kato Y,
Tsubota T and Fukada Y: Activation of TGF-beta/activin signalling
resets the circadian clock through rapid induction of Dec1
transcripts. Nat Cell Boil. 10:1463–1469. 2008. View Article : Google Scholar
|
|
36
|
Bhawal UK, Ito Y, Tanimoto K, Sato F,
Fujimoto K, Kawamoto T, Sasahira T, Hamada N, Kuniyasu H, Arakawa
H, et al: IL-1β-mediated up-regulation of DEC1 in human gingiva
cells via the Akt pathway. J Cell Biochem. 113:3246–3253. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Yamada K, Kawata H, Shou Z, Mizutani T,
Noguchi T and Miyamoto K: Insulin induces the expression of the
SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway. J
Boil Chem. 278:30719–30724. 2003. View Article : Google Scholar
|
|
38
|
Ivanova AV, Ivanov SV,
Danilkovitch-Miagkova A and Lerman MI: Regulation of STRA13 by the
von Hippel-Lindau tumor suppressor protein, hypoxia, and the
UBC9/ubiquitin proteasome degradation pathway. J Biol Chem.
276:15306–15315. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Zhu Z, Wang YW, Ge DH, Lu M, Liu W, Xiong
J, Hu G, Li XP and Yang J: Downregulation of DEC1 contributes to
the neurotoxicity induced by MPP(+) by suppressing PI3K/Akt/GSK3β
pathway. CNS Neurosci Ther. 23:736–747. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Hu J, Mao Z, He S, Zhan Y, Ning R, Liu W,
Yan B and Yang J: Icariin protects against glucocorticoid induced
osteoporosis, increases the expression of the bone enhancer DEC1
and modulates the PI3K/Akt/GSK3β/β-catenin integrated signaling
pathway. Biochem Pharmacol. 136:109–121. 2017. View Article : Google Scholar : PubMed/NCBI
|
