Myositis ossificans of the masticatory muscle monitored over three generations: A case report and review of the literature

Li,Chenlin; Yang,Chi; Qiu,Weiliu; Qiu,Yangting; Jiang,Qian; Chen,Minjie

doi:10.3892/etm.2020.8491

April-2020 Volume 19 Issue 4

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April-2020 Volume 19 Issue 4

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Case Report Open Access

Myositis ossificans of the masticatory muscle monitored over three generations: A case report and review of the literature

Authors:
- Chenlin Li
- Chi Yang
- Weiliu Qiu
- Yangting Qiu
- Qian Jiang
- Minjie Chen
View Affiliations / Copyright

Affiliations: Department of Oral Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology, National Clinical Research Center of Stomatology, Shanghai 200011, P.R. China

Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 2622-2626
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Published online on: February 5, 2020

https://doi.org/10.3892/etm.2020.8491
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Abstract

Myositis ossificans (MO) is a rare disease and its major feature is the formation of heterotropic bone involving muscle or any other type of soft tissue (tendons, ligament, fascia and connective tissue). In the present study, a case report of a patient diagnosed with MO is presented. The diagnosis was established by evaluation of the medical history of the patient and the patient's family, as well as clinical data, radiology and post‑operative pathology. The patient underwent excision surgery of the calcified lesion. In addition, genomic DNA was examined from blood samples of the patient and the patient's father with their consent. A mutation in the non‑coding region was detected but any direct causative effect remains elusive. The present case report provided significant information with regard to the incidence of MO in four members of the same family assessed over three generations. The disease exhibited a unique localization in the maxillofacial region.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Myositis ossificans of the masticatory muscle monitored over three generations: A case report and review of the literature

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