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Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature

  • Authors:
    • Xiaoming Gao
    • Qian Cheng
    • Xiaofei Zhang
    • Guoyang Zhao
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212000, P.R. China, Department of Orthopedics, Tong Ren Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200336, P.R. China, Department of Gynecology and Obstetrics, Shanghai First Maternal and Infant Healthcare Hospital Affiliated to Shanghai Tongji University, Shanghai 200040, P.R. China
    Copyright: © Gao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2702-2706
    |
    Published online on: February 10, 2020
       https://doi.org/10.3892/etm.2020.8503
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Abstract

Osteopetrosis is a rare congenital bone disorder, characterized by systemic osteosclerosis due to a deficiency of or functional defect in osteoclasts. Autosomal dominant osteopetrosis (ADOP) is the most common form with a late onset, a stable condition, relatively few symptoms and a good prognosis. Few studies to date have reported successful total hip arthroplasty (THA) in patients with ADOP and its operative difficulties. We herein describe a case of left hip osteoarthritis in a patient with OP via THA in order to share our experience during the treatment process. The patient was a 52‑years‑old female with osteopetrosis who was referred to our department due to a history of left hip pain with activity limitation for 20 years. The patient reported no history of fracture or family history. The patient underwent THA in the left hip. At the 6‑month, 1‑ and 2‑year follow‑up, the components were in a good position and the patient remained asymptomatic and pain‑free. Therefore, THA may be a feasible treatment option when patients with ADOP suffer from painful hip osteoarthritis.
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1 

Palagano E, Menale C, Sobacchi C and Villa A: Genetics of Osteopetrosis. Curr Osteoporos Rep. 16:13–25. 2018.PubMed/NCBI View Article : Google Scholar

2 

Moreno Garcia MS and Del Río-Martínez PS: Osteopetrosis type II: Albers-Schonberg disease. Joint Bone Spine. 83(231)2016.PubMed/NCBI View Article : Google Scholar

3 

Pang Q, Chi Y, Zhao Z, Xing X, Li M, Wang O, Jiang Y, Liao R, Sun Y, Dong J and Xia W: Novel mutations of CLCN7 cause autosomal dominant Osteopetrosis type II (ADO-II) and intermediate autosomal recessive Osteopetrosis (IARO) in Chinese patients. Osteoporos Int. 27:1047–1055. 2016.PubMed/NCBI View Article : Google Scholar

4 

Machado Cde V, da Rocha MC and Telles PD: Infantile Osteopetrosis associated with osteomyelitis. BMJ Case Rep. 2015(pii: bcr2014208085)2015.PubMed/NCBI View Article : Google Scholar

5 

Stattin EL, Henning P, Klar J, McDermott E, Stecksen-Blicks C, Sandström PE, Kellgren TG, Rydén P, Hallmans G, Lönnerholm T, et al: SNX10 gene mutation leading to Osteopetrosis with dysfunctional osteoclasts. Sci Rep. 7(3012)2017.PubMed/NCBI View Article : Google Scholar

6 

Nour M: Infantile malignant Osteopetrosis. J Pediatrics. 163:1230–1230.e1. 2013. View Article : Google Scholar

7 

Saigal A, Gopal M, Mohanty N and Misra SR: Recurrent osteomyelitis of the mandible in Osteopetrosis: A common complication of an uncommon disease. BMJ Case Rep. 2015(pii: bcr2014208974)2015.PubMed/NCBI View Article : Google Scholar

8 

Alsahlawi A, Ekhzaimy A, Alshowair D and Ajlan A: Decompressive cranioplasty in a patient with osteopetrosis. World Neurosurg. 108:991.e1–991.e5. 2017.PubMed/NCBI View Article : Google Scholar

9 

Stella I, Vinchon M, Guerreschi P, De Berranger E and Bouacha I: Case update on cranial Osteopetrosis: Which is the role of the neurosurgeon? Childs Nerv Syst. 33:2181–2186. 2017.PubMed/NCBI View Article : Google Scholar

10 

Akutsu N, Koyama J, Kawamura A, Nagashima T, Taniguchi M and Kohmura E: Endoscopic third ventriculostomy for hydrocephalus in Osteopetrosis: A case report and review of the literature. Childs Nerv Syst. 34:991–994. 2018.PubMed/NCBI View Article : Google Scholar

11 

Mosayebi Z, Mirfazaelian H, Khademi B, Bagheri N and Daneshbod Y: Osteopetrosis in siblings. Intern Emerg Med. 11:615–616. 2016.PubMed/NCBI View Article : Google Scholar

12 

Butscheidt S, Rolvien T, Kornak U, Schmidt FN, Schinke T, Amling M and Oheim R: Clinical significance of DXA and HR-pQCT in autosomal dominant Osteopetrosis (ADO II). Calcif Tissue Int. 102:41–52. 2018.PubMed/NCBI View Article : Google Scholar

13 

Wu CC, Econs MJ, DiMeglio LA, Insogna KL, Levine MA, Orchard PJ, Miller WP, Petryk A, Rush ET, Shoback DM, et al: Diagnosis and management of Osteopetrosis: Consensus guidelines from the Osteopetrosis working group. J Clin Endocrinol Metab. 102:3111–3123. 2017.PubMed/NCBI View Article : Google Scholar

14 

Stark Z: Osteopetrosis. Orphanet J Rare Dis. 4(5)2009.PubMed/NCBI View Article : Google Scholar

15 

Hashemi Taheri AP, Radmard AR, Kooraki S, Behfar M, Pak N, Hamidieh AA and Ghavamzadeh A: Radiologic resolution of malignant infantile Osteopetrosis skeletal changes following hematopoietic stem cell transplantation. Pediatric Blood Cancer. 62:1645–1649. 2015.PubMed/NCBI View Article : Google Scholar

16 

Erkus S, Turgut A, Kose O and Kalenderer Ö: Management of early-onset hip osteoarthritis in an adolescent patient with OP tarda: A case report. J Pediatr Orthop B. 28:487–490. 2019.PubMed/NCBI View Article : Google Scholar

17 

Stepensky P, Grisariu S, Avni B, Zaidman I, Shadur B, Elpeleg O, Sirin M, Hoenig M, Schuetz C, Furlan I, et al: Stem cell transplantation for Osteopetrosis in patients beyond the age of 5 years. Blood Adv. 3:862–868. 2019.PubMed/NCBI View Article : Google Scholar

18 

Dunphy L, Warfield A and Williams R: Osteomyelitis of the mandible secondary to malignant infantile Osteopetrosis in an adult. BMJ Case Rep. 12(pii: e224452)2019.PubMed/NCBI View Article : Google Scholar

19 

Cao W, Wei W, Yu G, Wu Q and Qin M: Comparison of optic canal diameter in children with malignant infantile Osteopetrosis and normal children and the effects of hematopoietic stem cell transplantation on the optic canal diameter. J Pediatr Ophthalmol Strabismus. 56:35–42. 2019.PubMed/NCBI View Article : Google Scholar

20 

Overholt KM, Rose MJ, Joshi S, Herman GE, Bajwa R, Abu-Arja R, Rangarajan HG and Horwitz EM: Hematopoietic cell transplantation for a child with OSTM1 Osteopetrosis. Blood Adv. 1:279–281. 2017. View Article : Google Scholar

21 

Shadur B, Zaidman I, NaserEddin A, Lokshin E, Hussein F, Oron HC, Avni B, Grisariu S and Stepensky P: Successful hematopoietic stem cell transplantation for Osteopetrosis using reduced intensity conditioning. Pediatr Blood Cancer. 65(e27010)2018.PubMed/NCBI View Article : Google Scholar

22 

Maurizi A, Capulli M, Patel R, Curle A, Rucci N and Teti A: RNA interference therapy for autosomal dominant Osteopetrosis type 2 towards the preclinical development. Bone. 110:343–354. 2018.PubMed/NCBI View Article : Google Scholar

23 

Yamane K and Kai N: Anterior cervical arthrodesis for chronic hangman's fracture in a patient with Osteopetrosis: A case report. Arch Orthop Trauma Surg. 138:783–789. 2018.PubMed/NCBI View Article : Google Scholar

24 

Hasan O, Pathan AZ, Naqi H, Aqueel T, Hashmi P and Lakdawala RH: Inheritance patterns, challenges, and outcomes of fracture management in Osteopetrosis patients. CASE series and review of pertinent literature. Ann Med Surg (Lond). 36:191–198. 2018.PubMed/NCBI View Article : Google Scholar

25 

Teti A and Econs MJ: Osteopetroses, emphasizing potential approaches to treatment. Bone. 102:50–59. 2017.PubMed/NCBI View Article : Google Scholar

26 

Carvalho PHA, Moura LB, Real Gabrielli MF, Cabrini Gabrielli MA and Antonio Pereira Filho V: Maxillary osteomyelitis associated with Osteopetrosis: Systematic review. J Craniomaxillofac Surg. 46:1905–1910. 2018.PubMed/NCBI View Article : Google Scholar

27 

Wang J, Liang Y, Zhang Q, Jiao J and Kan W: Total joint arthroplasty in a patient with Osteopetrosis: 10-year follow-up. Orthopedics. 33:2010.doi: 10.3928/01477447-20100225-23. PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Gao X, Cheng Q, Zhang X and Zhao G: Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature. Exp Ther Med 19: 2702-2706, 2020.
APA
Gao, X., Cheng, Q., Zhang, X., & Zhao, G. (2020). Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature. Experimental and Therapeutic Medicine, 19, 2702-2706. https://doi.org/10.3892/etm.2020.8503
MLA
Gao, X., Cheng, Q., Zhang, X., Zhao, G."Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature". Experimental and Therapeutic Medicine 19.4 (2020): 2702-2706.
Chicago
Gao, X., Cheng, Q., Zhang, X., Zhao, G."Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature". Experimental and Therapeutic Medicine 19, no. 4 (2020): 2702-2706. https://doi.org/10.3892/etm.2020.8503
Copy and paste a formatted citation
x
Spandidos Publications style
Gao X, Cheng Q, Zhang X and Zhao G: Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature. Exp Ther Med 19: 2702-2706, 2020.
APA
Gao, X., Cheng, Q., Zhang, X., & Zhao, G. (2020). Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature. Experimental and Therapeutic Medicine, 19, 2702-2706. https://doi.org/10.3892/etm.2020.8503
MLA
Gao, X., Cheng, Q., Zhang, X., Zhao, G."Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature". Experimental and Therapeutic Medicine 19.4 (2020): 2702-2706.
Chicago
Gao, X., Cheng, Q., Zhang, X., Zhao, G."Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature". Experimental and Therapeutic Medicine 19, no. 4 (2020): 2702-2706. https://doi.org/10.3892/etm.2020.8503
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