Open Access

Comparison of early and delayed removal of dressing following primary closure of clean and contaminated surgical wounds: A systematic review and meta-analysis of randomized controlled trials

  • Authors:
    • Taijuan Zhang
    • Fujie Zhang
    • Zongnan Chen
    • Xiuling Cheng
  • View Affiliations

  • Published online on: March 11, 2020     https://doi.org/10.3892/etm.2020.8591
  • Pages: 3219-3226
  • Copyright : © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The usefulness of dressing a surgical wound beyond the first 24-48 h of surgery is currently a controversial issue. The aim of this meta-analysis was to compare the early and delayed removal of dressing following primary closure in the management of clean and contaminated surgical wounds. Systematic searches were conducted in various databases including Medline, Cochrane Controlled Register of Trials (CENTRAL), Scopus, and Embase from January, 1964 until October, 2019. We used the Cochrane risk of bias tool to assess the quality of published trials. We carried out a meta-analysis with random-effects model and reported pooled risk ratios (RR) with 95% confidence intervals (CIs). In total, we analysed 10 studies with 1,708 participants. All the studies were randomized controlled trials, while the majority of studies had unclear or high bias risks. Early dressing removal was favoured with respect to surgical site infection (pooled RR=0.89; 95% CI: 0.61 to 1.29), patient's perception on safety (pooled RR=0.60; 95% CI: 0.48 to 0.76) and comfort (pooled RR=0.95; 95% CI: 0.74 to 1.22), while the remaining outcomes favoured delayed dressing removal. However, none of the factors had statistically significant difference between two interventions except the patient's perception on safety. To summarize, delayed removal of dressing is not superior to early removal following primary closure of clean or clean-contaminated surgical wounds.

Related Articles

Journal Cover

May 2020
Volume 19 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
APA
Zhang, T., Zhang, F., Chen, Z., & Cheng, X. (2020). Comparison of early and delayed removal of dressing following primary closure of clean and contaminated surgical wounds: A systematic review and meta-analysis of randomized controlled trials. Experimental and Therapeutic Medicine, 19, 3219-3226. https://doi.org/10.3892/etm.2020.8591
MLA
Zhang, T., Zhang, F., Chen, Z., Cheng, X."Comparison of early and delayed removal of dressing following primary closure of clean and contaminated surgical wounds: A systematic review and meta-analysis of randomized controlled trials". Experimental and Therapeutic Medicine 19.5 (2020): 3219-3226.
Chicago
Zhang, T., Zhang, F., Chen, Z., Cheng, X."Comparison of early and delayed removal of dressing following primary closure of clean and contaminated surgical wounds: A systematic review and meta-analysis of randomized controlled trials". Experimental and Therapeutic Medicine 19, no. 5 (2020): 3219-3226. https://doi.org/10.3892/etm.2020.8591