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Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors

  • Authors:
    • Delia Timofte
    • Dorin Dragoș
    • Andra‑Elena Balcangiu‑Stroescu
    • Maria‑Daniela Tănăsescu
    • Daniela Gabriela Bălan
    • Laura Răducu
    • Adrian Tulin
    • Ovidiu Stiru
    • Dorin Ionescu
  • View Affiliations / Copyright

    Affiliations: Department of Dialysis, Emergency University Hospital, 050098 Bucharest, Romania, Department of Medical Semiology, Discipline of Internal Medicine I and Nephrology, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Discipline of Physiology, Faculty of Dental Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Plastic and Reconstructive Microsurgery, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Anatomy, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Cardiovascular Surgery, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania
    Copyright: © Timofte et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 97-102
    |
    Published online on: March 17, 2020
       https://doi.org/10.3892/etm.2020.8607
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Abstract

Cardiovascular disease is the main cause of morbidity and mortality in end‑stage renal disease (ESRD) patients. Recent population based epidemiological studies demonstrated a correlation between reduced renal function and risk for all causes and cardiovascular mortality, 50% of patients dying before the commencement of renal replacement therapy. Vascular calcifications (VC) and arterial stiffness are major contributors to cardiovascular disease and are independent predictors of cardiovascular mortality in ESRD patients. Scarce information is available on the risk factors and prognosis of predialysis patients with VC. The aim of this study was to evaluate the contribution of traditional and uremia related risk factors to abdominal aortic calcification in predialysis patients. A single center, retrospective study was performed on 305 adult patients monitored at the Bucharest University Emergency Hospital for at least 6 months. Our study reports an increased incidence of VC in predialysis chronic kidney disease (CKD) patients, higher in those with advanced age, history of cardiovascular disease, osteoporosis, and declining renal function.
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Copy and paste a formatted citation
Spandidos Publications style
Timofte D, Dragoș D, Balcangiu‑Stroescu AE, Tănăsescu MD, Bălan DG, Răducu L, Tulin A, Stiru O and Ionescu D: Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors. Exp Ther Med 20: 97-102, 2020.
APA
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D.G., Răducu, L. ... Ionescu, D. (2020). Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors. Experimental and Therapeutic Medicine, 20, 97-102. https://doi.org/10.3892/etm.2020.8607
MLA
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D. G., Răducu, L., Tulin, A., Stiru, O., Ionescu, D."Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors". Experimental and Therapeutic Medicine 20.1 (2020): 97-102.
Chicago
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D. G., Răducu, L., Tulin, A., Stiru, O., Ionescu, D."Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors". Experimental and Therapeutic Medicine 20, no. 1 (2020): 97-102. https://doi.org/10.3892/etm.2020.8607
Copy and paste a formatted citation
x
Spandidos Publications style
Timofte D, Dragoș D, Balcangiu‑Stroescu AE, Tănăsescu MD, Bălan DG, Răducu L, Tulin A, Stiru O and Ionescu D: Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors. Exp Ther Med 20: 97-102, 2020.
APA
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D.G., Răducu, L. ... Ionescu, D. (2020). Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors. Experimental and Therapeutic Medicine, 20, 97-102. https://doi.org/10.3892/etm.2020.8607
MLA
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D. G., Răducu, L., Tulin, A., Stiru, O., Ionescu, D."Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors". Experimental and Therapeutic Medicine 20.1 (2020): 97-102.
Chicago
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D. G., Răducu, L., Tulin, A., Stiru, O., Ionescu, D."Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors". Experimental and Therapeutic Medicine 20, no. 1 (2020): 97-102. https://doi.org/10.3892/etm.2020.8607
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