Open Access

Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors

  • Authors:
    • Delia Timofte
    • Dorin Dragoș
    • Andra‑Elena Balcangiu‑Stroescu
    • Maria‑Daniela Tănăsescu
    • Daniela Gabriela Bălan
    • Laura Răducu
    • Adrian Tulin
    • Ovidiu Stiru
    • Dorin Ionescu
  • View Affiliations

  • Published online on: March 17, 2020     https://doi.org/10.3892/etm.2020.8607
  • Pages: 97-102
  • Copyright: © Timofte et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cardiovascular disease is the main cause of morbidity and mortality in end‑stage renal disease (ESRD) patients. Recent population based epidemiological studies demonstrated a correlation between reduced renal function and risk for all causes and cardiovascular mortality, 50% of patients dying before the commencement of renal replacement therapy. Vascular calcifications (VC) and arterial stiffness are major contributors to cardiovascular disease and are independent predictors of cardiovascular mortality in ESRD patients. Scarce information is available on the risk factors and prognosis of predialysis patients with VC. The aim of this study was to evaluate the contribution of traditional and uremia related risk factors to abdominal aortic calcification in predialysis patients. A single center, retrospective study was performed on 305 adult patients monitored at the Bucharest University Emergency Hospital for at least 6 months. Our study reports an increased incidence of VC in predialysis chronic kidney disease (CKD) patients, higher in those with advanced age, history of cardiovascular disease, osteoporosis, and declining renal function.
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July-2020
Volume 20 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Timofte D, Dragoș D, Balcangiu‑Stroescu AE, Tănăsescu MD, Bălan DG, Răducu L, Tulin A, Stiru O and Ionescu D: Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors. Exp Ther Med 20: 97-102, 2020
APA
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D.G., Răducu, L. ... Ionescu, D. (2020). Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors. Experimental and Therapeutic Medicine, 20, 97-102. https://doi.org/10.3892/etm.2020.8607
MLA
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D. G., Răducu, L., Tulin, A., Stiru, O., Ionescu, D."Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors". Experimental and Therapeutic Medicine 20.1 (2020): 97-102.
Chicago
Timofte, D., Dragoș, D., Balcangiu‑Stroescu, A., Tănăsescu, M., Bălan, D. G., Răducu, L., Tulin, A., Stiru, O., Ionescu, D."Abdominal aortic calcification in predialysis patients: Contribution of traditional and uremia‑related risk factors". Experimental and Therapeutic Medicine 20, no. 1 (2020): 97-102. https://doi.org/10.3892/etm.2020.8607