|
1
|
Chai Q, Liu Z and Chen L: Effects of
streptozotocin-induced diabetes on Kv channels in rat small
coronary smooth muscle cells. Chin J Physiol. 48:57–63.
2005.PubMed/NCBI
|
|
2
|
Bubolz AH, Li H, Wu Q and Liu Y: Enhanced
oxidative stress impairs cAMP-mediated dilation by reducing Kv
channel function in small coronary arteries of diabetic rats. Am J
Physiol Heart Circ Physiol. 289:H1873–H1880. 2005.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Chai Q, Xu X, Jia Q, Dong Q, Liu Z, Zhang
W and Chen L: Molecular basis of dysfunctional Kv channels in small
coronary artery smooth muscle cells of streptozotocin-induced
diabetic rats. Chin J Physiol. 50:171–177. 2007.PubMed/NCBI
|
|
4
|
Jackson R, Brennan S, Fielding P, Sims MW,
Challiss RA, Adlam D, Squire IB and Rainbow RD: Distinct and
complementary roles for alpha and beta isoenzymes of PKC in
mediating vasoconstrictor responses to acutely elevated glucose. Br
J Pharmacol. 173:870–887. 2016.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Liu Y, Terata K, Rusch NJ and Gutterman
DD: High glucose impairs voltage-gated K(+) channel current in rat
small coronary arteries. Circ Res. 89:146–152. 2001.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Garg A, Garg S, Zaneveld LJ and Singla AK:
Chemistry and pharmacology of the citrus bioflavonoid hesperidin.
Phytother Res. 15:655–669. 2001.PubMed/NCBI View
Article : Google Scholar
|
|
7
|
Knekt P, Kumpulainen J, Järvinen R,
Rissanen H, Heliövaara M, Reunanen A, Hakulinen T and Aromaa A:
Flavonoid intake and risk of chronic diseases. Am J Clin Nutr.
76:560–568. 2002.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Morand C, Dubray C, Milenkovic D, Lioger
D, Martin JF, Scalbert A and Mazur A: Hesperidin contributes to the
vascular protective effects of orange juice: A randomized crossover
study in healthy volunteers. Am J Clin Nutr. 93:73–80.
2011.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Rendeiro C, Dong H, Saunders C, Harkness
L, Blaze M, Hou Y, Belanger RL, Corona G, Lovegrove JA and Spencer
JPE: Flavanone-rich citrus beverages counteract the transient
decline in postprandial endothelial function in humans: A
randomised, controlled, double-masked, cross-over intervention
study. Br J Nutr. 116:1999–2010. 2016.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Choi EJ: Antioxidative effects of
hesperetin against 7,12-dimethylbenz(a)anthracene-induced oxidative
stress in mice. Life Sci. 82:1059–1064. 2008.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Kim JY, Jung KJ, Choi JS and Chung HY:
Hesperetin: A potent antioxidant against peroxynitrite. Free Radic
Res. 38:761–769. 2004.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Pollard SE, Whiteman M and Spencer JP:
Modulation of peroxynitrite-induced fibroblast injury by hesperet
in: A role for intracellular scavenging and modulation of ERK
signalling. Biochem Biophy Res Commun. 347:916–923. 2006.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Morin B, Nichols LA, Zalasky KM, Davis JW,
Manthey JA and Holland LJ: The citrus flavonoids hesperetin and
nobiletin differentially regulate low density lipoprotein receptor
gene transcription in HepG2 liver cells. J Nutr. 138:1274–1281.
2008.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Hirata A, Murakami Y, Shoji M, Kadoma Y
and Fujisawa S: Kinetics of radical-scavenging activity of
hesperetin and hesperidin and their inhibitory activity on COX-2
expression. Anticancer Res. 25:3367–3374. 2005.PubMed/NCBI
|
|
15
|
Huang SM, Tsai SY, Lin JA, Wu CH and Yen
GC: Cytoprotective effects of hesperetin and hesperidin against
amyloid beta-induced impairment of glucose transport through
downregulation of neuronal autophagy. Mol Nutr Food Res.
56:601–609. 2012.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Trivedi PP, Kushwaha S, Tripathi DN and
Jena GB: Cardioprotective effects of hesperetin against
doxorubicin-induced oxidative stress and DNA damage in rat.
Cardiovasc Toxicol. 11:215–225. 2011.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Yamamoto M, Suzuki A and Hase T:
Short-Term effects of glucosyl hesperidin and hesperetin on blood
pressure and vascular endothelial function in spontaneously
hypertensive rats. J Nutr Sci Vitaminol (Tokyo). 54:95–98.
2008.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Jin YR, Han XH, Zhang YH, Lee JJ, Lim Y,
Chung JH and Yun YP: Antiplatelet activity of hesperetin, a
bioflavonoid, is mainly mediated by inhibition of PLC-gamma2
phosphorylation and cyclooxygenase-1 activity. Atherosclerosis.
194:144–152. 2007.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Shih CH, Lin LH, Hsu HT, Wang KH, Lai CY,
Chen CM and Ko WC: Hesperetin, a selective phosphodiesterase 4
inhibitor, effectively suppresses ovalbumin-induced airway
hyperresponsiveness without influencing xylazine/ketamine-induced
anesthesia. Evid Based Complement Alternat Med.
2012(472897)2012.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Kumar B, Gupta SK, Srinivasan BP, Nag TC,
Srivastava S and Saxena R: Hesperetin ameliorates hyperglycemia
induced retinal vasculopathy via anti-angiogenic effects in
experimental diabetic rats. Vascul Pharmacol. 57:201–207.
2012.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Jin YR, Han XH, Zhang YH, Lee JJ, Lim Y,
Kim TJ, Yoo HS and Yun YP: Hesperetin, a bioflavonoid, inhibits rat
aortic vascular smooth muscle cells proliferation by arresting cell
cycle. J Cell Biochem. 104:1–14. 2008.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Orallo F, Alvarez E, Basaran H and Lugnier
C: Comparative study of the vasorelaxant activity,
superoxide-scavenging ability and cyclic nucleotide
phosphodiesterase-inhibitory effects of hesperetin and hesperidin.
Naunyn Schmiedebergs Arch Pharmacol. 370:452–463. 2004.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Liu L, Xu DM and Cheng YY: Distinct
effects of naringenin and hesperetin on nitric oxide production
from endothelial cells. J Agric Food Chem. 56:824–829.
2008.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Takumi H, Nakamura H, Simizu T, Harada R,
Kometani T, Nadamoto T, Mukai R, Murota K, Kawai Y and Terao J:
Bioavailability of orally administered water-dispersible hesperetin
and its effect on peripheral vasodilatation in human subjects:
Implication of endothelial functions of plasma conjugated
metabolites. Food Funct. 3:389–398. 2012.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Calderone V, Chericoni S, Martinelli C,
Testai L, Nardi A, Morelli I, Breschi MC and Martinotti E:
Vasorelaxing effects of flavonoids: Investigation on the possible
involvement of potassium channels. Naunyn Schmiedebergs Arch
Pharmacol. 370:290–298. 2004.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Liu Y, Niu L, Cui L, Hou X, Li J, Zhang X
and Zhang M: Hesperetin inhibits rat coronary constriction by
inhibiting Ca(2+) influx and enhancing voltage-gated K(+) channel
currents of the myocytes. Eur J Pharmacol. 735:193–201.
2014.PubMed/NCBI View Article : Google Scholar
|
|
27
|
McGrath JC and Lilley E: Implementing
guidelines on reporting research using animals (ARRIVE etc.): New
requirements for publication in BJP. Br J Pharmacol. 172:3189–3193.
2015.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Scholey JW and Meyer TW: Control of
glomerular hypertension by insulin administration in diabetic rats.
J Clin Invest. 83:1384–1389. 1989.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Kanaze FI, Bounartzi MI, Georgarakis M and
Niopas I: Pharmacokinetics of the citrus flavanone aglycones
hesperetin and naringenin after single oral administration in human
subjects. Eur J Clin Nutr. 61:472–477. 2007.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Kumar B, Gupta SK, Srinivasan BP, Nag TC,
Srivastava S, Saxena R and Jha KA: Hesperetin rescues retinal
oxidative stress, neuroinflammation and apoptosis in diabetic rats.
Microvasc Res. 87:65–74. 2013.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Cogolludo A, Moreno L, Bosca L, Tamargo J
and Perez-Vizcaino F: Thromboxane A2-induced inhibition of
voltage-gated K+ channels and pulmonary vasoconstriction: Role of
protein kinase Czeta. Circ Res. 93:656–663. 2003.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Gradel AKJ, Salomonsson M, Sorensen CM,
Holstein-Rathlou NH and Jensen LJ: Long-term diet-induced
hypertension in rats is associated with reduced expression and
function of small artery SKCa, IKCa, and Kir2.1 channels. Clin Sci
(Lond). 132:461–474. 2018.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Albarwani S, Nemetz LT, Madden JA, Tobin
AA, England SK, Pratt PF and Rusch N: Voltage-Gated K+ channels in
rat small cerebral arteries: Molecular identity of the functional
channels. J Physiol. 551:751–763. 2003.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Shen X, Li H, Li W, Wu X and Ding X:
Pioglitazone prevents hyperglycemia induced decrease of AdipoR1 and
AdipoR2 in coronary arteries and coronary VSMCs. Mol Cell
Endocrinol. 363:27–35. 2012.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Li H, Chai Q, Gutterman DD and Liu Y:
Elevated glucose impairs cAMP-mediated dilation by reducing Kv
channel activity in rat small coronary smooth muscle cells. Am J
Physiol Heart Circ Physiol. 285:H1213–H1219. 2003.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Dick GM, Bratz IN, Borbouse L, Payne GA,
Dincer UD, Knudson JD, Rogers PA and Tune JD: Voltage-Dependent K+
channels regulate the duration of reactive hyperemia in the canine
coronary circulation. Am J Physiol Heart Circ Physiol.
294:H2371–H2381. 2008.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Ohanyan V, Yin L, Bardakjian R, Kolz C,
Enrick M, Hakobyan T, Kmetz J, Bratz I, Luli J, Nagane M, et al:
Requisite role of kv1.5 channels in coronary metabolic dilation.
Circ Res. 117:612–621. 2015.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Gheibi S, Kashfi K and Ghasemi A: A
practical guide for induction of type-2 diabetes in rat:
Incorporating a high-fat diet and streptozotocin. Biomed
Pharmacother. 95:605–613. 2017.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Fang XK, Gao J and Zhu DN: Kaempferol and
quercetin isolated from Euonymus alatus improve glucose uptake of
3T3-L1 cells without adipogenesis activity. Life Sci. 82:615–622.
2008.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Yang DK and Kang HS: Anti-Diabetic effect
of cotreatment with quercetin and resveratrol in
streptozotocin-induced diabetic rats. Biomol Ther (Seoul).
26:130–138. 2018.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Wright IK, Amirchetty-Rao S and Kendall
DA: Potentiation by forskolin of both SNP- and ANP-stimulated
cyclic GMP accumulation in porcine isolated palmar lateral vein. Br
J Pharmacol. 112:1146–1150. 1994.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Elms SC, Toque HA, Rojas M, Xu Z, Caldwell
RW and Caldwell RB: The role of arginase I in diabetes-induced
retinal vascular dysfunction in mouse and rat models of diabetes.
Diabetologia. 56:654–662. 2013.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Mokhtar SS, Vanhoutte PM, Leung SW,
Suppian R, Yusof MI and Rasool AH: Reduced nitric oxide-mediated
relaxation and endothelial nitric oxide synthase expression in the
tail arteries of streptozotocin-induced diabetic rats. Eur J
Pharmacol. 773:78–84. 2016.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Malakul W, Thirawarapan S, Ingkaninan K
and Sawasdee P: Effects of kaempferia parviflora wall. Ex baker on
endothelial dysfunction in streptozotocin-induced diabetic rats. J
Ethnopharmacol. 133:371–377. 2011.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Goulopoulou S, Hannan JL, Matsumoto T,
Ogbi S, Ergul A and Webb RC: Reduced vascular responses to soluble
guanylyl cyclase but increased sensitivity to sildenafil in female
rats with type 2 diabetes. Am J Physiol Heart Circ Physiol.
309:H297–H304. 2015.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Radovi T, Bömicke T, Kökény G, Arif R,
Loganathan S, Kécsán K, Korkmaz S, Barnucz E, Sandner P, Karck M
and Szabó G: The phosphodiesterase-5 inhibitor vardenafil improves
cardiovascular dysfunction in experimental diabetes mellitus. Br J
Pharmacol. 156:909–919. 2009.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Wu GB, Zhou EX, Qing DX and Li J: Role of
potassium channels in regulation of rat coronary arteriole tone.
Eur J Pharmacol. 620:57–62. 2009.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Salomonsson M, Brasen JC and Sorensen CM:
Role of renal vascular potassium channels in physiology and
pathophysiology. Acta Physiol (Oxf). 221:14–31. 2017.PubMed/NCBI View Article : Google Scholar
|
|
50
|
Dick GM and Tune JD: Role of potassium
channels in coronary vasodilation. Exp Biol Med (Maywood).
235:10–22. 2010.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Berwick ZC, Moberly SP, Kohr MC, Morrical
EB, Kurian MM, Dick GM and Tune JD: Contribution of
voltage-dependent K+ and Ca2+ channels to coronary pressure-flow
autoregulation. Basic Res Cardiol. 107(264)2012.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Nishijima Y, Cao S, Chabowski DS,
Korishettar A, Ge A, Zheng X, Sparapani R, Gutterman DD and Zhang
DX: Contribution of KV1.5 channel to hydrogen peroxide-induced
human arteriolar dilation and its modulation by coronary artery
disease. Circ Res. 120:658–669. 2017.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Ohanyan V, Yin L, Bardakjian R, Kolz C,
Enrick M, Hakobyan T, Kmetz J, Bratz I, Luli J, Nagane M, et al:
Requisite role of kv1.5 channels in coronary metabolic dilation.
Circul Res. 117:612–621. 2015.PubMed/NCBI View Article : Google Scholar
|
|
54
|
Dong Y, Fernandes C, Liu Y, Wu Y, Wu H,
Brophy ML, Deng L, Song K, Wen A and Wong S: Role of endoplasmic
reticulum stress signalling in diabetic endothelial dysfunction and
atherosclerosis. Diab Vasc Dis Res. 14:14–23. 2017.PubMed/NCBI View Article : Google Scholar
|
|
55
|
Kerr PM, Clement-Chomienne O, Thorneloe
KS, Chen TT, Ishii K, Sontag DP, Walsh MP and Cole WC:
Heteromultimeric Kv1.2-Kv1.5 channels underlie
4-aminopyridine-sensitive delayed rectifier K(+) current of rabbit
vascular myocytes. Circ Res. 89:1038–1044. 2001.PubMed/NCBI View Article : Google Scholar
|
|
56
|
Thorneloe KS, Chen TT, Kerr PM, Grier EF,
Horowitz B, Cole WC and Walsh MP: Molecular composition of
4-aminopyridine-sensitive voltage-gated K(+) channels of vascular
smooth muscle. Circ Res. 89:1030–1037. 2001.PubMed/NCBI View Article : Google Scholar
|
|
57
|
Nieves-Cintrón M, Syed AU, Nystoriak MA
and Navedo MF: Regulation of voltage-gated potassium channels in
vascular smooth muscle during hypertension and metabolic disorders.
Microcirculation. 25:2018.PubMed/NCBI View Article : Google Scholar
|
