Open Access

Natural skin‑whitening compounds for the treatment of melanogenesis (Review)

  • Authors:
    • Wenhui Qian
    • Wenya Liu
    • Dong Zhu
    • Yanli Cao
    • Anfu Tang
    • Guangming Gong
    • Hua Su
  • View Affiliations

  • Published online on: April 24, 2020     https://doi.org/10.3892/etm.2020.8687
  • Pages: 173-185
  • Copyright: © Qian et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Melanogenesis is the process for the production of melanin, which is the primary cause of human skin pigmentation. Skin‑whitening agents are commercially available for those who wish to have a lighter skin complexions. To date, although numerous natural compounds have been proposed to alleviate hyperpigmentation, insufficient attention has been focused on potential natural skin‑whitening agents and their mechanism of action from the perspective of compound classification. In the present article, the synthetic process of melanogenesis and associated core signaling pathways are summarized. An overview of the list of natural skin‑lightening agents, along with their compound classifications, is also presented, where their efficacy based on their respective mechanisms of action on melanogenesis is discussed.

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July 2020
Volume 20 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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APA
Qian, W., Liu, W., Zhu, D., Cao, Y., Tang, A., Gong, G., & Su, H. (2020). Natural skin‑whitening compounds for the treatment of melanogenesis (Review). Experimental and Therapeutic Medicine, 20, 173-185. https://doi.org/10.3892/etm.2020.8687
MLA
Qian, W., Liu, W., Zhu, D., Cao, Y., Tang, A., Gong, G., Su, H."Natural skin‑whitening compounds for the treatment of melanogenesis (Review)". Experimental and Therapeutic Medicine 20.1 (2020): 173-185.
Chicago
Qian, W., Liu, W., Zhu, D., Cao, Y., Tang, A., Gong, G., Su, H."Natural skin‑whitening compounds for the treatment of melanogenesis (Review)". Experimental and Therapeutic Medicine 20, no. 1 (2020): 173-185. https://doi.org/10.3892/etm.2020.8687