Impact of obesity on the prognosis of hypertensive disorders in pregnancy

Bohiltea,Roxana   Elena; Zugravu,Corina‑Aurelia; Nemescu,Dragos; Turcan,Natalia; Paulet,Florina‑Paula; Gherghiceanu,Florentina; Ducu,Ionita; Cirstoiu,Monica   Mihaela

doi:10.3892/etm.2020.8783

September-2020 Volume 20 Issue 3

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September-2020 Volume 20 Issue 3

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Article Open Access

Impact of obesity on the prognosis of hypertensive disorders in pregnancy

Authors:
- Roxana Elena Bohiltea
- Corina‑Aurelia Zugravu
- Dragos Nemescu
- Natalia Turcan
- Florina‑Paula Paulet
- Florentina Gherghiceanu
- Ionita Ducu
- Monica Mihaela Cirstoiu
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Affiliations: Department of Obstetrics and Gynecology, ‘Carol Davila’ University of Medicine and Pharmacy, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania, Department of Food Hygiene and Nutrition, ‘Carol Davila’ University of Medicine and Pharmacy, 050463 Bucharest, Romania, Department of Obstetrics and Gynecology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, Department of Obstetrics and Gynecology, ‘Carol Davila’ University of Medicine and Pharmacy Doctoral School, University Emergency Hospital of Bucharest, 050098 Bucharest, Romania, Department of Marketing and Medical Technology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania

Copyright: © Bohiltea et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 2423-2428
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Published online on: May 21, 2020

https://doi.org/10.3892/etm.2020.8783
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Abstract

The prevalence of pathologies due to placental dysfunction superimposed on pregnancy is constantly increasing. The prognosis of the cases complicated by gestational hypertension is usually good, significantly better compared with that of the cases associating preeclampsia. About half of the cases with gestational hypertension will progress to preeclampsia, the risk of decompensation being inversely proportional to the gestational age of the onset of gestational hypertension. The present study, analyzed the cases of pregnancy and postpartum complicated by pathologies related to placental dysfunction, during a period of 5 years. The risk factors analyzed were the presence of infections during pregnancy, diabetes, thrombophilia, pregnancy obtained by in vitro fertilization, abnormal adherence of the placenta, obesity, multiple pregnancy, the presence of an earlier hepatic, endocrine, renal, cardiac or autoimmune pathology, and the existence of an uterine malformation. Obesity appears with a significantly increased incidence in patients with gestational hypertension and middle preeclampsia. Intrauterine growth restriction appears with a significantly increased incidence in patients with mild preeclampsia. Complications such as prematurity, acute fetal distress and abruption of placentae had a significantly increased incidence in patients with severe preeclampsia. Thus, obese patients have a higher risk of moderate preeclampsia, following gestational hypertension and finally severe preeclampsia.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Impact of obesity on the prognosis of hypertensive disorders in pregnancy

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