Paraganglioma presenting as a mesenteric cystic mass: A case report

Iliesiu,Andreea; Ungureanu,Irena   Antonia; Petca,Aida; Constantin,Maria   Magdalena; Petca,Razvan‑Cosmin; Sandru,Florica; Constantin,Traian; Dumitrascu,Mihai   Cristian

doi:10.3892/etm.2020.8805

September-2020 Volume 20 Issue 3

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September-2020 Volume 20 Issue 3

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Case Report

Paraganglioma presenting as a mesenteric cystic mass: A case report

Authors:
- Andreea Iliesiu
- Irena Antonia Ungureanu
- Aida Petca
- Maria Magdalena Constantin
- Razvan‑Cosmin Petca
- Florica Sandru
- Traian Constantin
- Mihai Cristian Dumitrascu
View Affiliations / Copyright

Affiliations: Department of Pathology, University and Emergency Hospital, 014461 Bucharest, Romania, Department 3 - Clinical Sciences, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department 3 - Clinical Sciences, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Urology, ‘Prof. Dr. Theodor Burghele’ Clinical Hospital, 050653 Bucharest, Romania
Pages: 2489-2492
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Published online on: May 28, 2020

https://doi.org/10.3892/etm.2020.8805
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Abstract

The present study aims to raise awareness about the necessity of a thorough differential diagnosis process when diagnosing paraganglioma as it is an extremely rare entity with a high malignant potential. A 64‑year‑old female patient was admitted to the hospital with symptoms of bowel obstruction and a palpable abdominal mass. Abdominal and pelvic computed tomography revealed a cystic heterogeneously enhanced mass. The tumor was surgically removed and then microscopically analysed. Microscopically, the mass was composed of nests of small polygonal and round cells with central vesicular nuclei, consistent with the diagnosis of mesenteric paraganglioma which was later confirmed by immunohistochemistry. The critical markers for paragangliomas, namely chromogranin A and S100, should be used as the first step in diagnosis, followed by other valuable immunohistochemical markers. A long‑term follow‑up is extremely important following the diagnosis of paraganglioma as all these tumors have a malignant potential.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Paraganglioma presenting as a mesenteric cystic mass: A case report

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Abstract

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