Variation of total serum sialic acid concentration in postmenopausal women

  • Authors:
    • Octavian Gabriel Olaru
    • Gianina Ioana Constantin
    • Catalina Monica Pena
  • View Affiliations

  • Published online on: June 11, 2020     https://doi.org/10.3892/etm.2020.8873
  • Pages: 2455-2459
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Abstract

Given its location and ubiquitous distribution, sialic acid can mediate or modulate a wide variety of physiological and pathological processes; however, there is scarce data regarding the associations between sialic acid serum levels and sex, age and menopause. The present study evaluated the age-related changes in serum sialic acid (SA) levels in 97 elderly subjects, including men and postmenopausal women. A significant increase in serum levels of sialic acid in postmenopausal women and a significant decrease in men were observed in an age-dependent manner. Furthermore, in postmenopausal women, positive correlations were observed between the total serum sialic acid level and age in all decades and subgroups. The total serum concentration of sialic acid in the postmenopausal women group exhibited a particular pattern; significantly lower levels were observed in subjects in the intermediate postmenopausal period compared with those in the first decade of post menopause and then higher levels again as the women get older (late climax), thus the concentration increased according to the age of the individual.

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September-2020
Volume 20 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Olaru OG, Constantin GI and Pena CM: Variation of total serum sialic acid concentration in postmenopausal women. Exp Ther Med 20: 2455-2459, 2020
APA
Olaru, O.G., Constantin, G.I., & Pena, C.M. (2020). Variation of total serum sialic acid concentration in postmenopausal women. Experimental and Therapeutic Medicine, 20, 2455-2459. https://doi.org/10.3892/etm.2020.8873
MLA
Olaru, O. G., Constantin, G. I., Pena, C. M."Variation of total serum sialic acid concentration in postmenopausal women". Experimental and Therapeutic Medicine 20.3 (2020): 2455-2459.
Chicago
Olaru, O. G., Constantin, G. I., Pena, C. M."Variation of total serum sialic acid concentration in postmenopausal women". Experimental and Therapeutic Medicine 20, no. 3 (2020): 2455-2459. https://doi.org/10.3892/etm.2020.8873