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Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County

  • Authors:
    • Roxana-Emanuela Popoiag
    • Eugenia Panaitescu
    • Andra-Iulia Suceveanu
    • Adrian-Paul Suceveanu
    • Sergiu Ioan Micu
    • Laura Mazilu
    • Irinel Parepa
    • Felix Voinea
    • Daniel Ovidiu Costea
    • Florin Enache
    • Carmen Fierbințeanu-Braticevici
  • View Affiliations / Copyright

    Affiliations: Department of Internal Medicine ‘Ovidius’ University, Faculty of Medicine, 900527 Constanta, Romania, Department of Informatics and Biostatistics, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Internal Medicine, Emergency Hospital, ‘Ovidius’ University, Faculty of Medicine, 900527 Constanta, Romania, Department of Oncology, Emergency Hospital, ‘Ovidius’ University, Faculty of Medicine, 900527 Constanta, Romania, Department of Cardiology, Emergency Hospital, ‘Ovidius’ University, Faculty of Medicine, 900527 Constanta, Romania, Department of Urology, Emergency Hospital, ‘Ovidius’ University, Faculty of Medicine, 900527 Constanta, Romania, Department of Surgery, Emergency Hospital, ‘Ovidius’ University, Faculty of Medicine, 900527 Constanta, Romania, Department of Pediatric Surgery, Emergency Hospital, ‘Ovidius’ University, Faculty of Medicine, 900527 Constanta, Romania, Department of Gastroenterology, University Hospital, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania
    Copyright: © Popoiag et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 732
    |
    Published online on: May 7, 2021
       https://doi.org/10.3892/etm.2021.10164
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Abstract

Spontaneous bacterial peritonitis (SBP) is a complication of liver cirrhosis with an increased in‑hospital mortality rate. For this reason, the aim of the present study was to examine the main predictors of mortality in order to be able to identify high‑risk patients in time and to guide the optimal treatment for prognosis improvement. We retrospectively collected demographic, clinical, laboratory and treatment data as well as data regarding length of stay and cost of hospitalization from 72 patients diagnosed with SBP between January 2010 and December 2019 in the Emergency Clinical Hospital St. Apostle Andrew, Constanta, Romania. Patients were divided into two groups: Those who survived and those who died. Logistic regression was used to identify a possible association between these factors and the increased risk of mortality. Univariate analysis revealed that clinical factors (fever, chills, and hepatic encephalopathy), biological factors such as serum and ascites leukocyte value, polymorphonuclear percentage (PMN), erythrocyte sedimentation rate (ESR) value, previous SBP episodes, and the presence of complications such as acute kidney injury (AKI), sepsis, and systemic inflammatory response syndrome (SIRS) were significantly associated with in‑hospital mortality in patients with SBP. Multivariate analysis revealed that SIRS (P=0.0010) and fever (P=0.0258) were significantly associated with in‑hospital mortality in patients with SBP. Findings of the present study suggest that, SIRS and fever were independent predictive factors of mortality in cirrhotic patients with SBP.
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Copy and paste a formatted citation
Spandidos Publications style
Popoiag R, Panaitescu E, Suceveanu A, Suceveanu A, Micu SI, Mazilu L, Parepa I, Voinea F, Costea DO, Enache F, Enache F, et al: Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County. Exp Ther Med 22: 732, 2021.
APA
Popoiag, R., Panaitescu, E., Suceveanu, A., Suceveanu, A., Micu, S.I., Mazilu, L. ... Fierbințeanu-Braticevici, C. (2021). Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County. Experimental and Therapeutic Medicine, 22, 732. https://doi.org/10.3892/etm.2021.10164
MLA
Popoiag, R., Panaitescu, E., Suceveanu, A., Suceveanu, A., Micu, S. I., Mazilu, L., Parepa, I., Voinea, F., Costea, D. O., Enache, F., Fierbințeanu-Braticevici, C."Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County". Experimental and Therapeutic Medicine 22.1 (2021): 732.
Chicago
Popoiag, R., Panaitescu, E., Suceveanu, A., Suceveanu, A., Micu, S. I., Mazilu, L., Parepa, I., Voinea, F., Costea, D. O., Enache, F., Fierbințeanu-Braticevici, C."Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County". Experimental and Therapeutic Medicine 22, no. 1 (2021): 732. https://doi.org/10.3892/etm.2021.10164
Copy and paste a formatted citation
x
Spandidos Publications style
Popoiag R, Panaitescu E, Suceveanu A, Suceveanu A, Micu SI, Mazilu L, Parepa I, Voinea F, Costea DO, Enache F, Enache F, et al: Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County. Exp Ther Med 22: 732, 2021.
APA
Popoiag, R., Panaitescu, E., Suceveanu, A., Suceveanu, A., Micu, S.I., Mazilu, L. ... Fierbințeanu-Braticevici, C. (2021). Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County. Experimental and Therapeutic Medicine, 22, 732. https://doi.org/10.3892/etm.2021.10164
MLA
Popoiag, R., Panaitescu, E., Suceveanu, A., Suceveanu, A., Micu, S. I., Mazilu, L., Parepa, I., Voinea, F., Costea, D. O., Enache, F., Fierbințeanu-Braticevici, C."Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County". Experimental and Therapeutic Medicine 22.1 (2021): 732.
Chicago
Popoiag, R., Panaitescu, E., Suceveanu, A., Suceveanu, A., Micu, S. I., Mazilu, L., Parepa, I., Voinea, F., Costea, D. O., Enache, F., Fierbințeanu-Braticevici, C."Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County". Experimental and Therapeutic Medicine 22, no. 1 (2021): 732. https://doi.org/10.3892/etm.2021.10164
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