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Review

COVID‑19‑related thyroid conditions (Review)

  • Authors:
    • Florica Șandru
    • Mara Carsote
    • Răzvan Cosmin Petca
    • Ancuta Augustina Gheorghisan-Galateanu
    • Aida Petca
    • Ana Valea
    • Mihai Cristian Dumitrașcu
  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Endocrinology, ‘C. I. Parhon’ National Institute of Endocrinology, 011863 Bucharest, Romania, Departament of Urology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474, Bucharest, Romania, Department of Obstetrics and Gynecology, ‘Elias’ Emergency University Hospital, 011461 Bucharest, Romania, Endocrinology Department, Clinical County Hospital, 400000 Cluj-Napoca, Romania, Departament of Obstetrics and Gynecology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474, Bucharest, Romania
  • Article Number: 756
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    Published online on: May 13, 2021
       https://doi.org/10.3892/etm.2021.10188
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Abstract

In patients who were not previously diagnosed with any thyroid conditions, the scenario of COVID‑19‑related anomalies of the hypothalamus‑pituitary‑thyroid axes may include either: A process of central thyroid stimulating hormone (TSH) disturbances via virus‑related hypophysitis; an atypical type of subacute thyroiditis which is connected to the virus spread or to excessive cytokine production including a destructive process with irreversible damage of the gland or low T3 (triiodothyronine) syndrome (so called non‑thyroid illness syndrome) which is not specifically related to the COVID‑19 infection, but which is associated with a very severe illness status. Our objective here was to briefly review thyroid changes due to the COVID‑19 infection. Ongoing assessment of the effects of the COVID‑19 pandemic will reveal more information on coronavirus‑induced thyroid conditions. Routine thyroid assays performed in patients with severe infection/at acute phase of COVID‑19 are encouraged in order to detect thyrotoxicosis. After recovery, thyroid function should be assessed to identify potential hypothyroidism. There remain unanswered questions related to the prognostic value of interleukin‑6 in infected patients, especially in cases with cytokine storm, and the necessity of thyroid hormone replacement in subjects with hypophysitis‑related central hypothyroidism.
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Copy and paste a formatted citation
Spandidos Publications style
Șandru F, Carsote M, Petca RC, Gheorghisan-Galateanu AA, Petca A, Valea A and Dumitrașcu MC: COVID‑19‑related thyroid conditions (Review). Exp Ther Med 22: 756, 2021.
APA
Șandru, F., Carsote, M., Petca, R.C., Gheorghisan-Galateanu, A.A., Petca, A., Valea, A., & Dumitrașcu, M.C. (2021). COVID‑19‑related thyroid conditions (Review). Experimental and Therapeutic Medicine, 22, 756. https://doi.org/10.3892/etm.2021.10188
MLA
Șandru, F., Carsote, M., Petca, R. C., Gheorghisan-Galateanu, A. A., Petca, A., Valea, A., Dumitrașcu, M. C."COVID‑19‑related thyroid conditions (Review)". Experimental and Therapeutic Medicine 22.1 (2021): 756.
Chicago
Șandru, F., Carsote, M., Petca, R. C., Gheorghisan-Galateanu, A. A., Petca, A., Valea, A., Dumitrașcu, M. C."COVID‑19‑related thyroid conditions (Review)". Experimental and Therapeutic Medicine 22, no. 1 (2021): 756. https://doi.org/10.3892/etm.2021.10188
Copy and paste a formatted citation
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Spandidos Publications style
Șandru F, Carsote M, Petca RC, Gheorghisan-Galateanu AA, Petca A, Valea A and Dumitrașcu MC: COVID‑19‑related thyroid conditions (Review). Exp Ther Med 22: 756, 2021.
APA
Șandru, F., Carsote, M., Petca, R.C., Gheorghisan-Galateanu, A.A., Petca, A., Valea, A., & Dumitrașcu, M.C. (2021). COVID‑19‑related thyroid conditions (Review). Experimental and Therapeutic Medicine, 22, 756. https://doi.org/10.3892/etm.2021.10188
MLA
Șandru, F., Carsote, M., Petca, R. C., Gheorghisan-Galateanu, A. A., Petca, A., Valea, A., Dumitrașcu, M. C."COVID‑19‑related thyroid conditions (Review)". Experimental and Therapeutic Medicine 22.1 (2021): 756.
Chicago
Șandru, F., Carsote, M., Petca, R. C., Gheorghisan-Galateanu, A. A., Petca, A., Valea, A., Dumitrașcu, M. C."COVID‑19‑related thyroid conditions (Review)". Experimental and Therapeutic Medicine 22, no. 1 (2021): 756. https://doi.org/10.3892/etm.2021.10188
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