COVID‑19‑related thyroid conditions (Review)

  • Authors:
    • Florica Șandru
    • Mara Carsote
    • Răzvan Cosmin Petca
    • Ancuta Augustina Gheorghisan-Galateanu
    • Aida Petca
    • Ana Valea
    • Mihai Cristian Dumitrașcu
  • View Affiliations

  • Published online on: May 13, 2021     https://doi.org/10.3892/etm.2021.10188
  • Article Number: 756
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Abstract

In patients who were not previously diagnosed with any thyroid conditions, the scenario of COVID‑19‑related anomalies of the hypothalamus‑pituitary‑thyroid axes may include either: A process of central thyroid stimulating hormone (TSH) disturbances via virus‑related hypophysitis; an atypical type of subacute thyroiditis which is connected to the virus spread or to excessive cytokine production including a destructive process with irreversible damage of the gland or low T3 (triiodothyronine) syndrome (so called non‑thyroid illness syndrome) which is not specifically related to the COVID‑19 infection, but which is associated with a very severe illness status. Our objective here was to briefly review thyroid changes due to the COVID‑19 infection. Ongoing assessment of the effects of the COVID‑19 pandemic will reveal more information on coronavirus‑induced thyroid conditions. Routine thyroid assays performed in patients with severe infection/at acute phase of COVID‑19 are encouraged in order to detect thyrotoxicosis. After recovery, thyroid function should be assessed to identify potential hypothyroidism. There remain unanswered questions related to the prognostic value of interleukin‑6 in infected patients, especially in cases with cytokine storm, and the necessity of thyroid hormone replacement in subjects with hypophysitis‑related central hypothyroidism.
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July-2021
Volume 22 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Șandru F, Carsote M, Petca RC, Gheorghisan-Galateanu AA, Petca A, Valea A and Dumitrașcu MC: COVID‑19‑related thyroid conditions (Review). Exp Ther Med 22: 756, 2021
APA
Șandru, F., Carsote, M., Petca, R.C., Gheorghisan-Galateanu, A.A., Petca, A., Valea, A., & Dumitrașcu, M.C. (2021). COVID‑19‑related thyroid conditions (Review). Experimental and Therapeutic Medicine, 22, 756. https://doi.org/10.3892/etm.2021.10188
MLA
Șandru, F., Carsote, M., Petca, R. C., Gheorghisan-Galateanu, A. A., Petca, A., Valea, A., Dumitrașcu, M. C."COVID‑19‑related thyroid conditions (Review)". Experimental and Therapeutic Medicine 22.1 (2021): 756.
Chicago
Șandru, F., Carsote, M., Petca, R. C., Gheorghisan-Galateanu, A. A., Petca, A., Valea, A., Dumitrașcu, M. C."COVID‑19‑related thyroid conditions (Review)". Experimental and Therapeutic Medicine 22, no. 1 (2021): 756. https://doi.org/10.3892/etm.2021.10188