Clinical and therapeutic features of acute cholecystitis in diabetic patients

  • Authors:
    • Dragos Serban
    • Simona Andreea Balasescu
    • Catalin Alius
    • Cristian Balalau
    • Alexandru Dan Sabau
    • Cristinel Dumitru Badiu
    • Bogdan Socea
    • Andra Maria Trotea
    • Ana Maria Dascalu
    • Ion Motofei
    • Valeriu Ardeleanu
    • Radu Iulian Spataru
    • Dan Sabau
    • Gabriel Catalin Smarandache
  • View Affiliations

  • Published online on: May 13, 2021     https://doi.org/10.3892/etm.2021.10190
  • Article Number: 758
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Abstract

The present study aimed to compare the clinical, paraclinical, intraoperative findings, and postoperative complications in acute cholecystitis in diabetic patients vs. non‑diabetic patients. A 2‑year retrospective study was performed on the patients who underwent emergency cholecystectomy for acute cholecystitis between 2017 and 2019 at the 4th Department of Surgery, Emergency University Hospital Bucharest. The diabetic subgroup numbered 46 eligible patients and the non‑diabetic one 287 patients. Demographics, the severity of the clinical forms, biological variables (including white cell count, urea, creatinine, coagulation and liver function tests) comorbidity status, surgical approach, postoperative complications, and hospital stay were analyzed. Statistical analyses were performed to assess comparative results between the aforementioned data (SPSS V 13.0). The CCI and ASA risk classes were increased in the diabetic group, with 34.78% of patients having 3 or more associated comorbidities. No statistically significant associations were demonstrated between diabetes and the severity of the cholecystitis and risk for conversion. Postoperatively both minor complications such as surgical site infections and major cardiovascular events were more common in the diabetic subgroup (P=0.0254), well associated with the preoperative status and baseline cardiovascular comorbidities. Laparoscopic cholecystectomy is a safe procedure for diabetic patients, which can provide the best outcomes, by decreasing the risks of surgical wounds. Attentive perioperative care and good glycemic control must be provided to minimize the risk of complications.
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July-2021
Volume 22 Issue 1

Print ISSN: 1792-0981
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Spandidos Publications style
Serban D, Balasescu SA, Alius C, Balalau C, Sabau AD, Badiu CD, Socea B, Trotea AM, Dascalu AM, Motofei I, Motofei I, et al: Clinical and therapeutic features of acute cholecystitis in diabetic patients. Exp Ther Med 22: 758, 2021
APA
Serban, D., Balasescu, S.A., Alius, C., Balalau, C., Sabau, A.D., Badiu, C.D. ... Smarandache, G.C. (2021). Clinical and therapeutic features of acute cholecystitis in diabetic patients. Experimental and Therapeutic Medicine, 22, 758. https://doi.org/10.3892/etm.2021.10190
MLA
Serban, D., Balasescu, S. A., Alius, C., Balalau, C., Sabau, A. D., Badiu, C. D., Socea, B., Trotea, A. M., Dascalu, A. M., Motofei, I., Ardeleanu, V., Spataru, R. I., Sabau, D., Smarandache, G. C."Clinical and therapeutic features of acute cholecystitis in diabetic patients". Experimental and Therapeutic Medicine 22.1 (2021): 758.
Chicago
Serban, D., Balasescu, S. A., Alius, C., Balalau, C., Sabau, A. D., Badiu, C. D., Socea, B., Trotea, A. M., Dascalu, A. M., Motofei, I., Ardeleanu, V., Spataru, R. I., Sabau, D., Smarandache, G. C."Clinical and therapeutic features of acute cholecystitis in diabetic patients". Experimental and Therapeutic Medicine 22, no. 1 (2021): 758. https://doi.org/10.3892/etm.2021.10190