Open Access

Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review)

  • Authors:
    • Floris Petru Iliuta
    • Mihnea Costin Manea
    • Magdalena Budisteanu
    • Adela Magdalena Ciobanu
    • Mirela Manea
  • View Affiliations

  • Published online on: May 14, 2021     https://doi.org/10.3892/etm.2021.10197
  • Article Number: 765
  • Copyright: © Iliuta et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Schizophrenia, one of the most common psychiatric disorders, with a worldwide annual incidence rate of approximately 0.3‑0.7%, known to affect the population below 25 years of age, is persistent throughout lifetime and includes people from all layers of society. With recent technological progress that allows better imaging techniques, such as the ones provided by computed tomography and particularly magnetic resonance imaging (MRI), research on schizophrenia imaging has grown considerably. The purpose of this review is to establish the importance of using imaging techniques in the early detection of brain abnormalities in patients diagnosed with schizophrenia. We reviewed all articles which reported on MRI imaging in schizophrenia. In order to do this, we used the PubMed database, using as search words ‘MRI’ and ‘schizophrenia’. MRI studies of first episode patients and chronic patients, suggest reduction of the whole brain volume. Enlargement of lateral ventricles was described as positive in 15 studies out of 19 and was similar to findings in chronic patients. Moreover, for the first episode patients, all data collected point to important changes in medial temporal lobe structures, diminished hippocampal volume, the whole frontal lobe, asymmetry in prefrontal cortex, diminished volume in cingulate, corpus callosum, and cavum septum pellucidum reported abnormalities. MRI is recommended as an important tool in the follow‑up process of patients with schizophrenia. Yet, it is still under debate whether the abnormalities described in this condition are able to be used as diagnostic biomarkers.
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July-2021
Volume 22 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Iliuta FP, Manea MC, Budisteanu M, Ciobanu AM and Manea M: Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review). Exp Ther Med 22: 765, 2021
APA
Iliuta, F.P., Manea, M.C., Budisteanu, M., Ciobanu, A.M., & Manea, M. (2021). Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review). Experimental and Therapeutic Medicine, 22, 765. https://doi.org/10.3892/etm.2021.10197
MLA
Iliuta, F. P., Manea, M. C., Budisteanu, M., Ciobanu, A. M., Manea, M."Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review)". Experimental and Therapeutic Medicine 22.1 (2021): 765.
Chicago
Iliuta, F. P., Manea, M. C., Budisteanu, M., Ciobanu, A. M., Manea, M."Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review)". Experimental and Therapeutic Medicine 22, no. 1 (2021): 765. https://doi.org/10.3892/etm.2021.10197