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Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review)

  • Authors:
    • Floris Petru Iliuta
    • Mihnea Costin Manea
    • Magdalena Budisteanu
    • Adela Magdalena Ciobanu
    • Mirela Manea
  • View Affiliations / Copyright

    Affiliations: Psychiatry Research Laboratory, ‘Prof. Dr. Alexandru Obregia’ Clinical Hospital of Psychiatry, 041914 Bucharest, Romania, Department of Neuroscience, Discipline of Psychiatry, Faculty of General Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania
    Copyright: © Iliuta et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 765
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    Published online on: May 14, 2021
       https://doi.org/10.3892/etm.2021.10197
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Abstract

Schizophrenia, one of the most common psychiatric disorders, with a worldwide annual incidence rate of approximately 0.3‑0.7%, known to affect the population below 25 years of age, is persistent throughout lifetime and includes people from all layers of society. With recent technological progress that allows better imaging techniques, such as the ones provided by computed tomography and particularly magnetic resonance imaging (MRI), research on schizophrenia imaging has grown considerably. The purpose of this review is to establish the importance of using imaging techniques in the early detection of brain abnormalities in patients diagnosed with schizophrenia. We reviewed all articles which reported on MRI imaging in schizophrenia. In order to do this, we used the PubMed database, using as search words ‘MRI’ and ‘schizophrenia’. MRI studies of first episode patients and chronic patients, suggest reduction of the whole brain volume. Enlargement of lateral ventricles was described as positive in 15 studies out of 19 and was similar to findings in chronic patients. Moreover, for the first episode patients, all data collected point to important changes in medial temporal lobe structures, diminished hippocampal volume, the whole frontal lobe, asymmetry in prefrontal cortex, diminished volume in cingulate, corpus callosum, and cavum septum pellucidum reported abnormalities. MRI is recommended as an important tool in the follow‑up process of patients with schizophrenia. Yet, it is still under debate whether the abnormalities described in this condition are able to be used as diagnostic biomarkers.
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Copy and paste a formatted citation
Spandidos Publications style
Iliuta FP, Manea MC, Budisteanu M, Ciobanu AM and Manea M: Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review). Exp Ther Med 22: 765, 2021.
APA
Iliuta, F.P., Manea, M.C., Budisteanu, M., Ciobanu, A.M., & Manea, M. (2021). Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review). Experimental and Therapeutic Medicine, 22, 765. https://doi.org/10.3892/etm.2021.10197
MLA
Iliuta, F. P., Manea, M. C., Budisteanu, M., Ciobanu, A. M., Manea, M."Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review)". Experimental and Therapeutic Medicine 22.1 (2021): 765.
Chicago
Iliuta, F. P., Manea, M. C., Budisteanu, M., Ciobanu, A. M., Manea, M."Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review)". Experimental and Therapeutic Medicine 22, no. 1 (2021): 765. https://doi.org/10.3892/etm.2021.10197
Copy and paste a formatted citation
x
Spandidos Publications style
Iliuta FP, Manea MC, Budisteanu M, Ciobanu AM and Manea M: Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review). Exp Ther Med 22: 765, 2021.
APA
Iliuta, F.P., Manea, M.C., Budisteanu, M., Ciobanu, A.M., & Manea, M. (2021). Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review). Experimental and Therapeutic Medicine, 22, 765. https://doi.org/10.3892/etm.2021.10197
MLA
Iliuta, F. P., Manea, M. C., Budisteanu, M., Ciobanu, A. M., Manea, M."Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review)". Experimental and Therapeutic Medicine 22.1 (2021): 765.
Chicago
Iliuta, F. P., Manea, M. C., Budisteanu, M., Ciobanu, A. M., Manea, M."Magnetic resonance imaging in schizophrenia: Luxury or necessity? (Review)". Experimental and Therapeutic Medicine 22, no. 1 (2021): 765. https://doi.org/10.3892/etm.2021.10197
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