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Lipoblastoma: Diagnosis and surgical considerations

  • Authors:
    • Radu-Iulian Spătaru
    • Cătălin Cîrstoveanu
    • Dan-Alexandru Iozsa
    • Augustina Enculescu
    • Luminița Florentina Tomescu
    • Dragoș Șerban
  • View Affiliations / Copyright

    Affiliations: Discipline of Pediatric Surgery, Faculty of Medicine, ʻCarol Davila’, University of Medicine and Pharmacy, 020021 Bucharest, Romania, Discipline of Pediatrics, Faculty of Medicine, ʻCarol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Pathology, ‘Maria S. Curie’ Emergency Clinic Hospital for Children, 41451 Bucharest, Romania, Department of Interventional Radiology, ‘Prof. Dr. Agrippa Ionescu’ Clinical Emergency Hospital, 011356 Bucharest, Romania, Discipline of General Surgery, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania
    Copyright: © Spătaru et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 903
    |
    Published online on: June 24, 2021
       https://doi.org/10.3892/etm.2021.10335
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Abstract

Lipoblastoma (LB) and lipoblastomatosis (LBS) are uncommon benign mesenchymal tumors of embryonal fat, occurring almost exclusively in infancy and early childhood. These fast‑growing tumors have an excellent prognosis if properly treated. Eight consecutive children having pathologically demonstrated LB treated by the same surgical team were retrospectively reviewed. There were 5 boys and 3 girls between 7 to 36 months (median age 22 months). The localization of the tumors was on the thigh (1 case), abdomen (2 cases), axillary and pectoral region (1 case) paragluteal region (1 case), lumbar area (1 case), inguinal‑scrotal (1 case), and in one case, presacral, gluteal and perirectal region (1 case). Five were focal and in 3 cases an infiltrative growth pattern was observed. One case exhibited a gross appearance resembling sacrococcygeal teratoma, with associated Dravet syndrome. No recurrence was noted in our series, after a mean follow‑up of 28 months post operatory. Despite its rareness, LB must be kept in mind when diagnosing a rapidly growing fatty mass in children. Even when dealing with very large abdominal LB, complete surgical excision is possible, with an excellent prognosis. Due to the relatively high recurrence rate noted in the literature, particularly in LBS, follow‑up is extremely important.
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Copy and paste a formatted citation
Spandidos Publications style
Spătaru R, Cîrstoveanu C, Iozsa D, Enculescu A, Tomescu LF and Șerban D: Lipoblastoma: Diagnosis and surgical considerations. Exp Ther Med 22: 903, 2021.
APA
Spătaru, R., Cîrstoveanu, C., Iozsa, D., Enculescu, A., Tomescu, L.F., & Șerban, D. (2021). Lipoblastoma: Diagnosis and surgical considerations. Experimental and Therapeutic Medicine, 22, 903. https://doi.org/10.3892/etm.2021.10335
MLA
Spătaru, R., Cîrstoveanu, C., Iozsa, D., Enculescu, A., Tomescu, L. F., Șerban, D."Lipoblastoma: Diagnosis and surgical considerations". Experimental and Therapeutic Medicine 22.2 (2021): 903.
Chicago
Spătaru, R., Cîrstoveanu, C., Iozsa, D., Enculescu, A., Tomescu, L. F., Șerban, D."Lipoblastoma: Diagnosis and surgical considerations". Experimental and Therapeutic Medicine 22, no. 2 (2021): 903. https://doi.org/10.3892/etm.2021.10335
Copy and paste a formatted citation
x
Spandidos Publications style
Spătaru R, Cîrstoveanu C, Iozsa D, Enculescu A, Tomescu LF and Șerban D: Lipoblastoma: Diagnosis and surgical considerations. Exp Ther Med 22: 903, 2021.
APA
Spătaru, R., Cîrstoveanu, C., Iozsa, D., Enculescu, A., Tomescu, L.F., & Șerban, D. (2021). Lipoblastoma: Diagnosis and surgical considerations. Experimental and Therapeutic Medicine, 22, 903. https://doi.org/10.3892/etm.2021.10335
MLA
Spătaru, R., Cîrstoveanu, C., Iozsa, D., Enculescu, A., Tomescu, L. F., Șerban, D."Lipoblastoma: Diagnosis and surgical considerations". Experimental and Therapeutic Medicine 22.2 (2021): 903.
Chicago
Spătaru, R., Cîrstoveanu, C., Iozsa, D., Enculescu, A., Tomescu, L. F., Șerban, D."Lipoblastoma: Diagnosis and surgical considerations". Experimental and Therapeutic Medicine 22, no. 2 (2021): 903. https://doi.org/10.3892/etm.2021.10335
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