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Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas

Retraction in: /10.3892/etm.2025.12951
  • Authors:
    • Yanbin Song
    • Lei Bai
    • Feiping Yan
    • Chen Chen
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, The First Hospital of Yulin, Yulin, Shanxi 719000, P.R. China
    Copyright: © Song et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY_NC 4.0].
  • Article Number: 930
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    Published online on: July 1, 2021
       https://doi.org/10.3892/etm.2021.10362
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Abstract

MicroRNAs (miR) are a group of non‑coding, small RNAs, 18‑20 nucleotides in length, that are frequently involved in the development of a variety of different types of cancer, including glioma, which is a type of severe tumor in the brain. Previous studies reported that miR‑124 levels were downregulated in glioma specimens; however, the potential role of miR‑124 in glioma currently remains unclear. The present study performed experiments, including dual‑luciferase reporter assay (DLRA), MTT assay, transwell assay and flow cytometry, with the aim of elucidating the molecular mechanism of miR‑124 in glioma. The results indicated that miR‑124 expression was decreased in glioma tissues, accompanied by the increased expression of extracellular matrix metalloproteinase inducer (EMMPRIN). The expression of EMMPRIN was inhibited by miR‑124 transfection. The DLRA results revealed that EMMPRIN directly targets miR‑124. Furthermore, upon overexpression of miR‑124 in the U87 cells, cell proliferation was significantly inhibited, apoptosis was increased, and cell migration and invasion were decreased. Furthermore, tumor growth was blocked by miR‑124 in mice. Based on these results, the present study concluded that miR‑124 is critical for amelioration of glioma by targeting EMMPRIN, thereby acting as a tumor suppressor. Thus, miR‑124/EMMPRIN constitutes a plausible basis for the treatment of glioma.
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1 

Jansson M, von Heymann-Horan AB, Rasmussen BK, Albieri V, Frederiksen K, Suppli N, Dalton SO, Johansen C and Bidstrup PE: Risk for use of antidepressants, anxiolytics, and hypnotics in partners of glioma patients-A nationwide study covering 19 years of prescriptions. Psychooncology. 27:1930–1936. 2018.PubMed/NCBI View Article : Google Scholar

2 

Ostrom QT, Bauchet L, Davis FG, Deltour I, Fisher JL, Langer CE, Pekmezci M, Schwartzbaum JA, Turner MC, Walsh KM, et al: The epidemiology of glioma in adults: A ‘state of the science’ review. Neuro Oncol. 16:896–913. 2014.PubMed/NCBI View Article : Google Scholar

3 

Affronti ML, Jackman JG, McSherry F, Herndon JE II, Massey EC Jr, Lipp E, Desjardins A, Friedman HS, Vlahovic G and Peters KB: Phase II study to evaluate the efficacy and safety of rilotumumab and bevacizumab in subjects with recurrent malignant glioma. Oncologist. 23:889–e98. 2018.PubMed/NCBI View Article : Google Scholar

4 

Ravn MB, Jakola AS, Reinertsen I, Sagberg LM, Unsgard G and Solheim O: The diagnostic properties of intraoperative ultrasound in glioma surgery and factors associated with gross total tumor resection. World Neurosurg. 115:e129–e136. 2018.PubMed/NCBI View Article : Google Scholar

5 

Parente A, van Waarde A, Shoji A, de Paula FD, Maas B, Zijlma R, Dierckx R, Langendijk JA, de Vries EFJ and Doorduin J: PET imaging with S-[11 C]Methyl-L-cysteine and L-[Methyl-11 C]Methionine in rat models of glioma, glioma radiotherapy, and neuroinflammation. Mol Imaging Biol. 20:465–472. 2018.PubMed/NCBI View Article : Google Scholar

6 

Fang Y, Jiang Y, Zou Y, Meng F, Zhang J, Deng C, Sun H and Zhong Z: Targeted glioma chemotherapy by cyclic RGD peptide-functionalized reversibly core-crosslinked multifunctional poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles. Acta Biomater. 50:396–406. 2017.PubMed/NCBI View Article : Google Scholar

7 

Dai X, Ma C, Lan Q and Xu T: 3D bioprinted glioma stem cells for brain tumor model and applications of drug susceptibility. Biofabrication. 8(45005)2016.PubMed/NCBI View Article : Google Scholar

8 

Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, et al: A glial signature and Wnt7 signaling regulate glioma-vascular interactions and tumor microenvironment. Cancer Cell. 33:874–889.e7. 2018.PubMed/NCBI View Article : Google Scholar

9 

Ruan H, Chai Z, Shen Q, Chen X, Su B, Xie C, Zhan C, Yao S, Wang H, Zhang M, et al: A novel peptide ligand RAP12 of LRP1 for glioma targeted drug delivery. J Control Release. 279:306–315. 2018.PubMed/NCBI View Article : Google Scholar

10 

Khan MB, Schneider JR, Kwan K and Boockvar JA: Epigentic regulators of glioma stem cells are potential therapeutic targets. Neurosurgery. 82:E104–E105. 2018.PubMed/NCBI View Article : Google Scholar

11 

Kim H, Yi SS, Lee HK, Heo TH, Park SK, Jun HS, Song KD and Kim SJ: Antiproliferative effect of vine stem extract from spatholobus suberectus Dunn on Rat C6 glioma cells through regulation of ROS, mitochondrial depolarization, and P21 protein expression. Nutr Cancer. 70:605–619. 2018.PubMed/NCBI View Article : Google Scholar

12 

Nan Y, Guo H, Guo LY, Wang L, Ren BC, Yu K, Huang Q and Zhong Y: miRNA-451 inhibits glioma cell proliferation and invasion through the mTOR/HIF-1alpha/VEGF signaling pathway by targeting CAB39. Hum Gene Ther Clin Dev. 29:156–166. 2018.PubMed/NCBI View Article : Google Scholar

13 

Lu F, Ye Y, Zhang H, He X, Sun X, Yao C, Mao H, He X, Qian C, Wang B, et al: miR-497/Wnt3a/c-jun feedback loop regulates growth and epithelial-to-mesenchymal transition phenotype in glioma cells. Int J Biol Macromol. 120:985–991. 2018.PubMed/NCBI View Article : Google Scholar

14 

Chai C, Song LJ, Han SY, Li XQ and Li M: MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway. CNS Neurosci Ther. 24:369–380. 2018.PubMed/NCBI View Article : Google Scholar

15 

Hui W, Yuntao L, Lun L, WenSheng L, ChaoFeng L, HaiYong H and Yueyang B: MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1. PLoS One. 8(e54932)2013.PubMed/NCBI View Article : Google Scholar

16 

Yan D, Hao C, Xiao-Feng L, Yu-Chen L, Yu-Bin F and Lei Z: Molecular mechanism of Notch signaling with special emphasis on microRNAs: Implications for glioma. J Cell Physiol. 234:158–170. 2018.PubMed/NCBI View Article : Google Scholar

17 

Gu G, Wang L, Zhang J, Wang H, Tan T and Zhang G: MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42. Onco Targets Ther. 11:4075–4085. 2018.PubMed/NCBI View Article : Google Scholar

18 

Wu Q, Xu L, Wang C, Fan W, Yan H and Li Q: MicroRNA-124-3p represses cell growth and cell motility by targeting EphA2 in glioma. Biochem Biophys Res Commun. 503:2436–2442. 2018.PubMed/NCBI View Article : Google Scholar

19 

von Ungern-Sternberg SNI, Zernecke A and Seizer P: Extracellular matrix metalloproteinase inducer EMMPRIN (CD147) in cardiovascular disease. Int J Mol Sci. 19(507)2018.PubMed/NCBI View Article : Google Scholar

20 

Horikawa Y, Watanabe M, Sadahira T, Ariyoshi Y, Kobayashi Y, Araki M, Wada K, Ochiai K, Li SA and Nasu Y: Overexpression of REIC/Dkk-3 suppresses the expression of CD147 and inhibits the proliferation of human bladder cancer cells. Oncol Lett. 14:3223–3228. 2017.PubMed/NCBI View Article : Google Scholar

21 

Zhou Y, Di Z, Li X, Shan Y, Li W, Zhang H and Xiao Y: Chemical proteomics reveal CD147 as a functional target of Pseudolaric acid B in human cancer cells. Chem Commun (Camb). 53:8671–8674. 2017.PubMed/NCBI View Article : Google Scholar

22 

Jia L, Zhou H, Wang S, Cao J, Wei W and Zhang J: Deglycosylation of CD147 down-regulates Matrix Metalloproteinase-11 expression and the adhesive capability of murine hepatocarcinoma cell HcaF in vitro. IUBMB Life. 58:209–216. 2006.PubMed/NCBI View Article : Google Scholar

23 

Zhang Z, Zhao Y, Jiang L, Miao X, Zhou H and Jia L: Glycomic alterations are associated with multidrug resistance in human leukemia. Int J Biochem Cell Biol. 44:1244–1253. 2012.PubMed/NCBI View Article : Google Scholar

24 

Arora M and Mane DR: Immunohistochemical expression of extracellular matrix metalloproteinase inducer (EMMPRIN) in normal oral mucosa, oral epithelial dysplasia and oral squamous cell carcinoma. J Oral Maxillofac Pathol. 22:279–280. 2018.PubMed/NCBI View Article : Google Scholar

25 

Zheng HC and Gong BC: CD147 expression was positively linked to aggressiveness and worse prognosis of gastric cancer: A meta and bioinformatics analysis. Oncotarget. 8:90358–90370. 2017.PubMed/NCBI View Article : Google Scholar

26 

Yin H, Shao Y and Chen X: The effects of CD147 on the cell proliferation, apoptosis, invasion, and angiogenesis in glioma. Neurol Sci. 38:129–136. 2017.PubMed/NCBI View Article : Google Scholar

27 

Li H, Xi Z, Dai X, Wu W, Li Y, Liu Y and Zhang H: CD147 and glioma: A meta-analysis. J Neurooncol. 134:145–156. 2017.PubMed/NCBI View Article : Google Scholar

28 

Wijnenga M, French PJ, Dubbink HJ, Dinjens W, Atmodimedjo PN, Kros JM, Fleischeuer R, Dirven C, Vincent A and van den Bent MJ: Prognostic relevance of mutations and copy number alterations assessed with targeted next generation sequencing in IDH mutant grade II glioma. J Neurooncol. 139:349–357. 2018.PubMed/NCBI View Article : Google Scholar

29 

Andronesi OC, Arrillaga-Romany IC, Ly KI, Bogner W, Ratai EM, Reitz K, Iafrate AJ, Dietrich J, Gerstner ER, Chi AS, et al: Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate. Nat Commun. 9(1474)2018.PubMed/NCBI View Article : Google Scholar

30 

Subburayan K, Thayyullathil F, Pallichankandy S, Rahman A and Galadari S: Par-4-dependent p53 up-regulation plays a critical role in thymoquinone-induced cellular senescence in human malignant glioma cells. Cancer Lett. 426:80–97. 2018.PubMed/NCBI View Article : Google Scholar

31 

Liu SJ, Yang TC, Yang ST, Chen YC and Tseng YY: Biodegradable hybrid-structured nanofibrous membrane supported chemoprotective gene therapy enhances chemotherapy tolerance and efficacy in malignant glioma rats. Artif Cells Nanomed Biotechnol. 46 (Suppl 2):S515–S526. 2018.PubMed/NCBI View Article : Google Scholar

32 

Chen X, Li D, Gao Y, Cao Y and Hao B: Histone deacetylase SIRT6 inhibits glioma cell growth through down-regulating NOTCH3 expression. Acta Biochim Biophys Sin (Shanghai). 50:417–424. 2018.PubMed/NCBI View Article : Google Scholar

33 

Lee YS and Dutta A: MicroRNAs in cancer. Annu Rev Pathol. 4:199–227. 2009.PubMed/NCBI View Article : Google Scholar

34 

Cortez MA, Anfossi S, Ramapriyan R, Menon H, Atalar SC, Aliru M, Welsh J and Calin GA: Role of miRNAs in immune responses and immunotherapy in cancer. Genes Chromosomes Cancer. 58:244–253. 2019.PubMed/NCBI View Article : Google Scholar

35 

Hu C, Dong X, Wu J, Xiao F, Shang J, Liu L, Yang Y, Luo D, Li Q, Song Q, et al: CD147 overexpression may serve as a promising diagnostic and prognostic marker for gastric cancer: Evidence from original research and literature. Oncotarget. 8:30888–30899. 2017.PubMed/NCBI View Article : Google Scholar

36 

Zhang X, Tian T, Zhang X, Liu C and Fang X: Elevated CD147 expression is associated with shorter overall survival in non-small cell lung cancer. Oncotarget. 8:37673–37680. 2017.PubMed/NCBI View Article : Google Scholar

37 

Fei F, Li S, Fei Z and Chen Z: The roles of CD147 in the progression of gliomas. Expert Rev Anticancer Ther. 15:1351–1359. 2015.PubMed/NCBI View Article : Google Scholar

38 

Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, Koono M and Wakisaka S: Expression of emmprin (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas. Int J Cancer. 88:21–27. 2000.PubMed/NCBI View Article : Google Scholar

39 

Hu Z, Cai M, Deng L, Zhu L, Gao J, Tan M, Liu J and Lin B: The fucosylated CD147 enhances the autophagy in epithelial ovarian cancer cells. Oncotarget. 7:82921–82932. 2016.PubMed/NCBI View Article : Google Scholar

40 

Kendrick AA, Schafer J, Dzieciatkowska M, Nemkov T, D'Alessandro A, Neelakantan D, Ford HL, Pearson CG, Weekes CD, Hansen KC and Eisenmesser EZ: CD147: A small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming. Oncotarget. 8:6742–6762. 2017.PubMed/NCBI View Article : Google Scholar

41 

Martins SF, Amorim R, Viana-Pereira M, Pinheiro C, Costa RF, Silva P, Couto C, Alves S, Fernandes S, Vilaca S, et al: Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis. BMC Cancer. 16(535)2016.PubMed/NCBI View Article : Google Scholar

42 

Ju X, Liang S, Zhu J, Ke G, Wen H and Wu X: Extracellular matrix metalloproteinase inducer (CD147/BSG/EMMPRIN)-induced radioresistance in cervical cancer by regulating the percentage of the cells in the G2/m phase of the cell cycle and the repair of DNA double-strand breaks (DSBs). Am J Transl Res. 8:2498–2511. 2016.PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Song Y, Bai L, Yan F and Chen C: Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas Retraction in /10.3892/etm.2025.12951. Exp Ther Med 22: 930, 2021.
APA
Song, Y., Bai, L., Yan, F., & Chen, C. (2021). Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas Retraction in /10.3892/etm.2025.12951. Experimental and Therapeutic Medicine, 22, 930. https://doi.org/10.3892/etm.2021.10362
MLA
Song, Y., Bai, L., Yan, F., Chen, C."Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas Retraction in /10.3892/etm.2025.12951". Experimental and Therapeutic Medicine 22.3 (2021): 930.
Chicago
Song, Y., Bai, L., Yan, F., Chen, C."Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas Retraction in /10.3892/etm.2025.12951". Experimental and Therapeutic Medicine 22, no. 3 (2021): 930. https://doi.org/10.3892/etm.2021.10362
Copy and paste a formatted citation
x
Spandidos Publications style
Song Y, Bai L, Yan F and Chen C: Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas Retraction in /10.3892/etm.2025.12951. Exp Ther Med 22: 930, 2021.
APA
Song, Y., Bai, L., Yan, F., & Chen, C. (2021). Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas Retraction in /10.3892/etm.2025.12951. Experimental and Therapeutic Medicine, 22, 930. https://doi.org/10.3892/etm.2021.10362
MLA
Song, Y., Bai, L., Yan, F., Chen, C."Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas Retraction in /10.3892/etm.2025.12951". Experimental and Therapeutic Medicine 22.3 (2021): 930.
Chicago
Song, Y., Bai, L., Yan, F., Chen, C."Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas Retraction in /10.3892/etm.2025.12951". Experimental and Therapeutic Medicine 22, no. 3 (2021): 930. https://doi.org/10.3892/etm.2021.10362
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