Open Access

Corneal endothelial changes induced by pars plana vitrectomy with silicone oil tamponade for retinal detachment

  • Authors:
    • Corina Cristina Coman (Cernat)
    • Daniel Malita
    • Simona Stanca
    • Stella Ioana Patoni (Popescu)
    • Ovidiu Musat
    • Serban Negru
    • Horea Feier
    • Olimpiu Ladislau Karancsi
    • Cosmin Rosca
  • View Affiliations

  • Published online on: July 7, 2021     https://doi.org/10.3892/etm.2021.10393
  • Article Number: 961
  • Copyright: © Coman (Cernat) et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Silicone oils are effective intraocular tamponade agents in the treatment of severe retinal detachments, because they maintain the adhesion between neurosensory retina and retinal pigment epithelium, thanks to their ability to remove aqueous humor from the surface of the retina. To understand their effectiveness, it is important to know the characteristics of silicone oils. Patients should be closely monitored due to many complications associated with intraocular silicon oil, such as inflammatory reaction, raised intraocular pressure, refraction disorders, cataract, and emulsification. This study presents corneal endothelial changes and some intraocular complications caused by silicone oil used as an intraocular tamponade agent in the case of vitrectomy for complex retinal detachments. The aim of the study was to demonstrate the damage of corneal endothelial cells after the use of silicone oil in patients with retinal detachment surgery. Endothelial specular microscopy measurements were performed and the changes of the following parameters demonstrated the corneal damage: Mean cell density, coefficient of variation, average cell area, percentage of hexagonal cells, and corneal thickness. Three months postoperatively, a statistically significant decrease was observed in the following analyzed parameters: Mean cell density (P=0.04), and percentage of hexagonal cells (P=0.002); the remaining parameters also had a linear decrease (coefficient of variation, average cell area), but were statistically insignificant. Three months postoperatively, the corneal thickness presented a slight increase. Silicone oils are powerful tools when used wisely and within the limits of their use. These are often recommended in cases of severe detachment of the retina in patients at high risk of experiencing intraoperative complications.
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September-2021
Volume 22 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Coman (Cernat) CC, Malita D, Stanca S, Patoni (Popescu) SI, Musat O, Negru S, Feier H, Karancsi OL and Rosca C: Corneal endothelial changes induced by pars plana vitrectomy with silicone oil tamponade for retinal detachment. Exp Ther Med 22: 961, 2021
APA
Coman (Cernat), C.C., Malita, D., Stanca, S., Patoni (Popescu), S.I., Musat, O., Negru, S. ... Rosca, C. (2021). Corneal endothelial changes induced by pars plana vitrectomy with silicone oil tamponade for retinal detachment. Experimental and Therapeutic Medicine, 22, 961. https://doi.org/10.3892/etm.2021.10393
MLA
Coman (Cernat), C. C., Malita, D., Stanca, S., Patoni (Popescu), S. I., Musat, O., Negru, S., Feier, H., Karancsi, O. L., Rosca, C."Corneal endothelial changes induced by pars plana vitrectomy with silicone oil tamponade for retinal detachment". Experimental and Therapeutic Medicine 22.3 (2021): 961.
Chicago
Coman (Cernat), C. C., Malita, D., Stanca, S., Patoni (Popescu), S. I., Musat, O., Negru, S., Feier, H., Karancsi, O. L., Rosca, C."Corneal endothelial changes induced by pars plana vitrectomy with silicone oil tamponade for retinal detachment". Experimental and Therapeutic Medicine 22, no. 3 (2021): 961. https://doi.org/10.3892/etm.2021.10393