Open Access

Hanta hemorrhagic fever with renal syndrome: A pathology in whose diagnosis kidney biopsy plays a major role (Review)

  • Authors:
    • Gabriela Lupuşoru
    • Mircea Lupuşoru
    • Ioana Ailincăi
    • Lavinia Bernea
    • Andreea Berechet
    • Radu Spătaru
    • Gener Ismail
  • View Affiliations

  • Published online on: July 12, 2021     https://doi.org/10.3892/etm.2021.10416
  • Article Number: 984
  • Copyright: © Lupuşoru et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Hantavirus infection belongs to a group of zoonoses rare in the Balkan Peninsula, causing two major syndromes, depending on the viral serotype involved: Hemorrhagic fever with renal syndrome (HFRS) also known as endemic nephropathy and cardiopulmonary syndrome (CPS). Because there is no specific treatment or vaccine for this condition approved in the USA or Europe, the key to minimizing the risk of adverse progression to chronic kidney disease, secondary hypertension or even death is primarily the recognition and early diagnosis of this condition with prompt therapeutic intervention. The aim of this study was to review the literature data on the epidemiology, pathogenesis and management of this disease and to identify several aspects related to the difficulties encountered in diagnosing this pathology, taking into consideration that the disease is not endemic in this geographical area.

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September-2021
Volume 22 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Lupuşoru G, Lupuşoru M, Ailincăi I, Bernea L, Berechet A, Spătaru R and Ismail G: Hanta hemorrhagic fever with renal syndrome: A pathology in whose diagnosis kidney biopsy plays a major role (Review). Exp Ther Med 22: 984, 2021
APA
Lupuşoru, G., Lupuşoru, M., Ailincăi, I., Bernea, L., Berechet, A., Spătaru, R., & Ismail, G. (2021). Hanta hemorrhagic fever with renal syndrome: A pathology in whose diagnosis kidney biopsy plays a major role (Review). Experimental and Therapeutic Medicine, 22, 984. https://doi.org/10.3892/etm.2021.10416
MLA
Lupuşoru, G., Lupuşoru, M., Ailincăi, I., Bernea, L., Berechet, A., Spătaru, R., Ismail, G."Hanta hemorrhagic fever with renal syndrome: A pathology in whose diagnosis kidney biopsy plays a major role (Review)". Experimental and Therapeutic Medicine 22.3 (2021): 984.
Chicago
Lupuşoru, G., Lupuşoru, M., Ailincăi, I., Bernea, L., Berechet, A., Spătaru, R., Ismail, G."Hanta hemorrhagic fever with renal syndrome: A pathology in whose diagnosis kidney biopsy plays a major role (Review)". Experimental and Therapeutic Medicine 22, no. 3 (2021): 984. https://doi.org/10.3892/etm.2021.10416