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Therapeutic approaches in the management of knee osteoarthritis (Review)

  • Authors:
    • Bogdan Uivaraseanu
    • Cosmin Mihai Vesa
    • Delia Mirela Tit
    • Areha Abid
    • Octavian Maghiar
    • Teodor Andrei Maghiar
    • Calin Hozan
    • Aurelia Cristina Nechifor
    • Tapan Behl
    • Jenel Marian Patrascu
    • Simona Bungau
  • View Affiliations / Copyright

    Affiliations: Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, Oradea 410081, Romania, Department of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, Oradea 410081, Romania, Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea 410028, Romania, Department of Food Science, Faculty of Agricultural and Food Sciences, University of Debrecen, Debrecen 4032, Hungary, Department of Analytical Chemistry and Environmental Engineering, Polytechnic University of Bucharest, Bucharest 011061, Romania, Department of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, India, Department of Orthopedics, Urology and Medical Imaging, Faculty of Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara 300041, Romania
  • Article Number: 328
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    Published online on: March 15, 2022
       https://doi.org/10.3892/etm.2022.11257
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Abstract

Osteoarthritis (OA) is a common, frequently met degenerative disease, that generates pain and decreasing functionality; risk of suffering from this disorder increases with ageing. Being a complex disease, treatment is often difficult due to complications. Knee OA therapy demands a strategy that specialists agree with in considering the clinical symptoms and the disease evolution. The initial management of its treatment should be conservative requiring both a pharmacological and a non‑pharmacological approach. If this conservative, noninvasive therapy fails, the surgical approach is discussed. The present review focused on the assessment of therapy choices for patients with knee OA, in order to reduce pain and enhance functionality and knee range of motion, underlying benefits and advantages for each choice. Existing data of available treatment for knee OA, both surgical and nonsurgical were analyzed, focusing on the latest results, indications, developments, and level of evidence provided by the literature in the topic.
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Spandidos Publications style
Uivaraseanu B, Vesa CM, Tit DM, Abid A, Maghiar O, Maghiar TA, Hozan C, Nechifor AC, Behl T, Patrascu JM, Patrascu JM, et al: Therapeutic approaches in the management of knee osteoarthritis (Review). Exp Ther Med 23: 328, 2022.
APA
Uivaraseanu, B., Vesa, C.M., Tit, D.M., Abid, A., Maghiar, O., Maghiar, T.A. ... Bungau, S. (2022). Therapeutic approaches in the management of knee osteoarthritis (Review). Experimental and Therapeutic Medicine, 23, 328. https://doi.org/10.3892/etm.2022.11257
MLA
Uivaraseanu, B., Vesa, C. M., Tit, D. M., Abid, A., Maghiar, O., Maghiar, T. A., Hozan, C., Nechifor, A. C., Behl, T., Patrascu, J. M., Bungau, S."Therapeutic approaches in the management of knee osteoarthritis (Review)". Experimental and Therapeutic Medicine 23.5 (2022): 328.
Chicago
Uivaraseanu, B., Vesa, C. M., Tit, D. M., Abid, A., Maghiar, O., Maghiar, T. A., Hozan, C., Nechifor, A. C., Behl, T., Patrascu, J. M., Bungau, S."Therapeutic approaches in the management of knee osteoarthritis (Review)". Experimental and Therapeutic Medicine 23, no. 5 (2022): 328. https://doi.org/10.3892/etm.2022.11257
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Spandidos Publications style
Uivaraseanu B, Vesa CM, Tit DM, Abid A, Maghiar O, Maghiar TA, Hozan C, Nechifor AC, Behl T, Patrascu JM, Patrascu JM, et al: Therapeutic approaches in the management of knee osteoarthritis (Review). Exp Ther Med 23: 328, 2022.
APA
Uivaraseanu, B., Vesa, C.M., Tit, D.M., Abid, A., Maghiar, O., Maghiar, T.A. ... Bungau, S. (2022). Therapeutic approaches in the management of knee osteoarthritis (Review). Experimental and Therapeutic Medicine, 23, 328. https://doi.org/10.3892/etm.2022.11257
MLA
Uivaraseanu, B., Vesa, C. M., Tit, D. M., Abid, A., Maghiar, O., Maghiar, T. A., Hozan, C., Nechifor, A. C., Behl, T., Patrascu, J. M., Bungau, S."Therapeutic approaches in the management of knee osteoarthritis (Review)". Experimental and Therapeutic Medicine 23.5 (2022): 328.
Chicago
Uivaraseanu, B., Vesa, C. M., Tit, D. M., Abid, A., Maghiar, O., Maghiar, T. A., Hozan, C., Nechifor, A. C., Behl, T., Patrascu, J. M., Bungau, S."Therapeutic approaches in the management of knee osteoarthritis (Review)". Experimental and Therapeutic Medicine 23, no. 5 (2022): 328. https://doi.org/10.3892/etm.2022.11257
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