Synchronous arterial resection in pancreatic cancer: A case report

Bacalbasa,Nicolae; Balescu,Irina; Dimitriu,Mihai; Balalau,Cristian; Furtunescu,Florentina; Gherghiceanu,Florentina; Radavoi,Daniel; Diaconu,Camelia; Stiru,Ovidiu; Savu,Cornel; Brasoveanu,Vladislav; Stoica,Claudia; Cordos,Ioan

doi:10.3892/etm.2022.11258

May-2022 Volume 23 Issue 5

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May-2022 Volume 23 Issue 5

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Case Report

Synchronous arterial resection in pancreatic cancer: A case report

Authors:
- Nicolae Bacalbasa
- Irina Balescu
- Mihai Dimitriu
- Cristian Balalau
- Florentina Furtunescu
- Florentina Gherghiceanu
- Daniel Radavoi
- Camelia Diaconu
- Ovidiu Stiru
- Cornel Savu
- Vladislav Brasoveanu
- Claudia Stoica
- Ioan Cordos
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Affiliations: Department of Visceral Surgery, Center of Excellence in Translational Medicine, Fundeni Clinical Institute, 022328 Bucharest, Romania, Department of Surgery, Ponderas Academic Hospital, 014142 Bucharest, Romania, Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Surgery, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Public Health and Management, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Marketing and Medical Technology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Urology, Clinical Hospital Prof. Dr. Th. Burghele, 061344 Bucharest, Romania, Department of Internal Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Cardiovascular Surgery, Emergency Institute for Cardiovascular Diseases Prof. Dr. C. C. Iliescu, 022328 Bucharest, Romania, Department of Thoracic Surgery, Marius Nasta National Institute of Pneumology, 050159 Bucharest, Romania, Department of Surgery, Ilfov County Hospital, 077160 Bucharest, Romania
Article Number: 329
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Published online on: March 15, 2022

https://doi.org/10.3892/etm.2022.11258
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Abstract

Pancreatic cancer is one of the most lethal malignancies affecting people worldwide. As it is frequently diagnosed in advanced stages of the disease, the 5‑year overall survival rate is <10%. Advanced stages are usually characterized by the local invasion of the superior mesenteric axis, celiac axis and portal vein and are considered a sign of unresectable cancer. The association between venous resections and survival outcomes has been widely reported. The effect of arterial invasion remains unclear as only isolated cases have been reported thus far. The present study investigated the preliminary experience in the field of arterial resection for locally advanced pancreatic cancer. Between January 2018 and January 2020 arterial resection was successfully associated with pancreatoduodenectomy in four cases. The mean age at the time of surgery was 48 years, and in all cases the indication of resection was represented by pancreatic head adenocarcinoma. Different types of venous resections were required in all cases. Postoperative reoperation was required in one case, while histopathological studies confirmed microscopic negative resection margins in all but one case. In selected cases, combined pancreatoduodenectomy with venous and arterial resection may be required to increase the chances of radical surgery.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Synchronous arterial resection in pancreatic cancer: A case report

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