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Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report

  • Authors:
    • Zina Cuzmici‑Barabaș
    • Andreea Cătană
    • Mariela Sanda Militaru
    • Oana Garbea
    • Iuliu Vlad Cătană
    • Ioan Victor Pop
  • View Affiliations / Copyright

    Affiliations: Department of Molecular Sciences, University of Medicine and Pharmacy, 4000012 Cluj‑Napoca, Romania, Department of Otorhynolaringology, ‘Venart’ Clinic, 400486 Cluj Napoca, Romania
    Copyright: © Cuzmici‑Barabaș et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 387
    |
    Published online on: April 12, 2022
       https://doi.org/10.3892/etm.2022.11314
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Abstract

Sensorineural hearing loss (SSHL) with a sudden onset is frequently encountered as a medical emergency in the ear, nose and throat (ENT) practice. The exact pathophysiology of the disease remains unknown, with the most likely etiologies being viral infection, inflammation, drug toxicity, trauma, or autoimmune response. Even though thrombophilia and cerebrovascular complications may lead, among others, to sudden neurosensorial hearing loss, its diagnosis is most often made following the onset of thrombotic complications. A case of a young female patient with unknown congenital hypercoagulation status complicated with lateral sinus thrombosis and unilateral drug‑induced reversible hearing loss is presented. Molecular testing confirmed the diagnosis of genetic thrombophilia, due to the homozygous V Leiden, homozygous MTHFR A1298C, and heterozygous MTHFR C677T mutations. Although hereditary thrombophilia is a well‑known topic in medical practice, current guidelines require continuous improvement, especially among patients treated in departments where this pathology is more difficult to recognize and manage.
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Copy and paste a formatted citation
Spandidos Publications style
Cuzmici‑Barabaș Z, Cătană A, Militaru MS, Garbea O, Cătană IV and Pop IV: Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report. Exp Ther Med 23: 387, 2022.
APA
Cuzmici‑Barabaș, Z., Cătană, A., Militaru, M.S., Garbea, O., Cătană, I.V., & Pop, I.V. (2022). Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report. Experimental and Therapeutic Medicine, 23, 387. https://doi.org/10.3892/etm.2022.11314
MLA
Cuzmici‑Barabaș, Z., Cătană, A., Militaru, M. S., Garbea, O., Cătană, I. V., Pop, I. V."Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report". Experimental and Therapeutic Medicine 23.6 (2022): 387.
Chicago
Cuzmici‑Barabaș, Z., Cătană, A., Militaru, M. S., Garbea, O., Cătană, I. V., Pop, I. V."Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report". Experimental and Therapeutic Medicine 23, no. 6 (2022): 387. https://doi.org/10.3892/etm.2022.11314
Copy and paste a formatted citation
x
Spandidos Publications style
Cuzmici‑Barabaș Z, Cătană A, Militaru MS, Garbea O, Cătană IV and Pop IV: Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report. Exp Ther Med 23: 387, 2022.
APA
Cuzmici‑Barabaș, Z., Cătană, A., Militaru, M.S., Garbea, O., Cătană, I.V., & Pop, I.V. (2022). Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report. Experimental and Therapeutic Medicine, 23, 387. https://doi.org/10.3892/etm.2022.11314
MLA
Cuzmici‑Barabaș, Z., Cătană, A., Militaru, M. S., Garbea, O., Cătană, I. V., Pop, I. V."Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report". Experimental and Therapeutic Medicine 23.6 (2022): 387.
Chicago
Cuzmici‑Barabaș, Z., Cătană, A., Militaru, M. S., Garbea, O., Cătană, I. V., Pop, I. V."Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report". Experimental and Therapeutic Medicine 23, no. 6 (2022): 387. https://doi.org/10.3892/etm.2022.11314
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