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Case Report Open Access

Buschke‑Löwenstein tumors: A series of 7 case reports

  • Authors:
    • Daniel Boda
    • Ana Cutoiu
    • Dalia Bratu
    • Nona Bejinariu
    • Rodica Crutescu
  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, ‘Ponderas’ Academic Hospital, 014142 Bucharest, Romania, Department of Dermatology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Pathology, ‘Santomar’ Laboratory, 400350 Cluj‑Napoca, Romania
    Copyright: © Boda et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 393
    |
    Published online on: April 13, 2022
       https://doi.org/10.3892/etm.2022.11320
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Abstract

Giant condyloma acuminatum (GCA), or Buschke‑Löwenstein tumor (BLT), represents an infrequent sexually transmitted disease (STD), caused by human papillomavirus (HPV), especially genotype 6 or 11. There are numerous risk factors for HPV, such as multiple sexual partners, homosexuality, prostitution, chronic genital infections, as well as the lack of proper hygiene. HPV infection is a field infection, where large areas of cells at a tissue surface are affected by the HPV virus; therefore, once the GCA is excised, treatment of the whole affected genital area needs to be undertaken. The treatment is classified into topical therapy (podophyllin, 5‑FU, radiotherapy, topical photodynamic therapy), excisional therapy (CO2 laser, cryotherapy, electrotherapy, surgery) and immunotherapy (imiquimod). However, the ‘gold standard’ therapy is represented by wide surgical excision without grafting, since it is considered that healing per secundam is an improved approach, because there is no risk of recurrences on fibrotic tissue. A total of 7 cases of the BLT with comorbidities and particularities are presented and it is recommended that it be taken into consideration that the incidence of the disease is increasing, emphasizing the importance of an early diagnosis, as well as an adequate treatment.
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Copy and paste a formatted citation
Spandidos Publications style
Boda D, Cutoiu A, Bratu D, Bejinariu N and Crutescu R: Buschke‑Löwenstein tumors: A series of 7 case reports. Exp Ther Med 23: 393, 2022.
APA
Boda, D., Cutoiu, A., Bratu, D., Bejinariu, N., & Crutescu, R. (2022). Buschke‑Löwenstein tumors: A series of 7 case reports. Experimental and Therapeutic Medicine, 23, 393. https://doi.org/10.3892/etm.2022.11320
MLA
Boda, D., Cutoiu, A., Bratu, D., Bejinariu, N., Crutescu, R."Buschke‑Löwenstein tumors: A series of 7 case reports". Experimental and Therapeutic Medicine 23.6 (2022): 393.
Chicago
Boda, D., Cutoiu, A., Bratu, D., Bejinariu, N., Crutescu, R."Buschke‑Löwenstein tumors: A series of 7 case reports". Experimental and Therapeutic Medicine 23, no. 6 (2022): 393. https://doi.org/10.3892/etm.2022.11320
Copy and paste a formatted citation
x
Spandidos Publications style
Boda D, Cutoiu A, Bratu D, Bejinariu N and Crutescu R: Buschke‑Löwenstein tumors: A series of 7 case reports. Exp Ther Med 23: 393, 2022.
APA
Boda, D., Cutoiu, A., Bratu, D., Bejinariu, N., & Crutescu, R. (2022). Buschke‑Löwenstein tumors: A series of 7 case reports. Experimental and Therapeutic Medicine, 23, 393. https://doi.org/10.3892/etm.2022.11320
MLA
Boda, D., Cutoiu, A., Bratu, D., Bejinariu, N., Crutescu, R."Buschke‑Löwenstein tumors: A series of 7 case reports". Experimental and Therapeutic Medicine 23.6 (2022): 393.
Chicago
Boda, D., Cutoiu, A., Bratu, D., Bejinariu, N., Crutescu, R."Buschke‑Löwenstein tumors: A series of 7 case reports". Experimental and Therapeutic Medicine 23, no. 6 (2022): 393. https://doi.org/10.3892/etm.2022.11320
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