|
1
|
Hasan TF, Hasan H and Kelley RE: Overview
of acute ischemic stroke evaluation and management. Biomedicines.
9(1486)2021.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Huynh TV, Davis AA, Ulrich JD and Holtzman
DM: Apolipoprotein E and Alzheimer's disease: The influence of
apolipoprotein E on amyloid-β and other amyloidogenic proteins. J
Lipid Res. 58:824–836. 2017.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Michaelson DM: APOE ε4: The most prevalent
yet understudied risk factor for Alzheimer's disease. Alzheimers
Dement. 10:861–868. 2014.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Rub U, Stratmann K, Heinsen H, Turco DD,
Seidel K, Dunnen WD and Korf HW: The brainstem tau cytoskeletal
pathology of Alzheimer's Disease: A brief historical overview and
description of its anatomical distribution pattern, evolutional
features, pathogenetic and clinical relevance. Curr Alzheimer Res.
13:1178–1197. 2016.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Raffaello A, De Stefani D and Rizzuto R:
The mitochondrial Ca(2+) uniporter. Cell Calcium. 52:16–21.
2012.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Granatiero V, Pacifici M, Raffaello A, De
Stefani D and Rizzuto R: Overexpression of mitochondrial calcium
uniporter causes neuronal death. Oxid Med Cell Longev.
2019(1681254)2019.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Qiu J, Tan YW, Hagenston AM, Martel MA,
Kneisel N, Skehel PA, Wyllie DJA, Bading H and Hardingham GE:
Mitochondrial calcium uniporter Mcu controls excitotoxicity and is
transcriptionally repressed by neuroprotective nuclear calcium
signals. Nat Commun. 4(2034)2013.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Moreira PI, Carvalho C, Zhu X, Smith MA
and Perry G: Mitochondrial dysfunction is a trigger of Alzheimer's
disease pathophysiology. Biochim Biophys Acta. 1802:2–10.
2010.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Fu YJ, Xiong S, Lovell MA and Lynn BC:
Quantitative proteomic analysis of mitochondria in aging PS-1
transgenic mice. Cell Mol Neurobiol. 29:649–664. 2009.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Zhou X, Wang HY, Wu B, Cheng CY, Xiao W,
Wang ZZ, Yang YY, Li P and Yang H: Ginkgolide K attenuates neuronal
injury after ischemic stroke by inhibiting mitochondrial fission
and GSK-3β-dependent increases in mitochondrial membrane
permeability. Oncotarget. 8:44682–44693. 2017.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Zhang Y and Miao JM: Ginkgolide K promotes
astrocyte proliferation and migration after oxygen-glucose
deprivation via inducing protective autophagy through the
AMPK/mTOR/ULK1 signaling pathway. Eur J Pharmacol. 832:96–103.
2018.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Liu Q, Li X, Li L, Xu Z, Zhou J and Xiao
W: Ginkgolide K protects SHSY5Y cells against oxygenglucose
deprivationinduced injury by inhibiting the p38 and JNK signaling
pathways. Mol Med Rep. 18:3185–3192. 2018.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Chen M, Zou W, Chen M, Cao L, Ding J, Xiao
W and Hu G: Ginkgolide K promotes angiogenesis in a middle cerebral
artery occlusion mouse model via activating JAK2/STAT3 pathway. Eur
J Pharmacol. 833:221–229. 2018.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Ma S, Liu X, Xun Q and Zhang X:
Neuroprotective effect of ginkgolide k against H2O2-induced PC12
cell cytotoxicity by ameliorating mitochondrial dysfunction and
oxidative stress. Biol Pharm Bull. 37:217–225. 2014.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Kilkenny C, Browne W, Cuthill IC, Emerson
M and Altman DG: NC3Rs Reporting Guidelines Working Group. Animal
research: Reporting in vivo experiments: The ARRIVE guidelines. Br
J Pharmacol. 160:1577–1579. 2010.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Shao L, Dong C, Geng D, He Q and Shi Y:
Ginkgolide B protects against cognitive impairment in
senescence-accelerated P8 mice by mitigating oxidative stress,
inflammation and ferroptosis. Biochem Biophys Res Commun. 572:7–14.
2021.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Mulder GB and Pritchett K: The morris
water maze. Contemp Top Lab Anim Sci. 42:49–50. 2003.PubMed/NCBI
|
|
19
|
Su R, Su W and Jiao Q: NGF protects
neuroblastoma cells against beta-amyloid-induced apoptosis via the
Nrf2/HO-1 pathway. FEBS Open Bio. 9:2063–2071. 2019.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Ding Y, Zhang H, Liu Z, Li Q, Guo Y, Chen
Y, Chang Y and Cui H: Carnitine palmitoyltransferase 1 (CPT1)
alleviates oxidative stress and apoptosis of hippocampal neuron in
response to beta-Amyloid peptide fragment Abeta25-35.
Bioengineered. 12:5440–5449. 2021.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Morris R: Developments of a water-maze
procedure for studying spatial learning in the rat. J Neurosci
Methods. 11:47–60. 1984.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Jafari SMS and Hunger RE: IHC optical
density score: A new practical method for quantitative
immunohistochemistry image analysis. Appl Immunohistochem Mol
Morphol. 25:e12–e13. 2017.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Heggland I, Storkaas IS, Soligard HT,
Kobro-Flatmoen A and Witter MP: Stereological estimation of neuron
number and plaque load in the hippocampal region of a transgenic
rat model of Alzheimer's disease. Eur J Neurosci. 41:1245–1262.
2015.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Shen Y, Wang H, Sun Q, Yao H, Keegan AP,
Mullan M, Wilson J, Lista S, Leyhe T, Laske C, et al: Increased
Plasma beta-secretase 1 may predict conversion to Alzheimer's
disease dementia in individuals with mild cognitive impairment.
Biol Psychiatry. 83:447–455. 2018.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Butterfield DA, Castegna A, Lauderback CM
and Drake J: Evidence that amyloid beta-peptide-induced lipid
peroxidation and its sequelae in Alzheimer's disease brain
contribute to neuronal death. Neurobiol Aging. 23:655–664.
2002.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Carrillo-Mora P, Luna R and Colin-Barenque
L: Amyloid beta: Multiple mechanisms of toxicity and only some
protective effects? Oxid Med Cell Longev.
2014(795375)2014.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Arispe N, Pollard HB and Rojas E: Giant
multilevel cation channels formed by Alzheimer disease amyloid
beta-protein [A beta P-(1-40)] in bilayer membranes. Proc Natl Acad
Sci USA. 90:10573–10577. 1993.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Abramov AY, Canevari L and Duchen MR:
Changes in intracellular calcium and glutathione in astrocytes as
the primary mechanism of amyloid neurotoxicity. J Neurosci.
23:5088–5095. 2003.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Tatebayashi Y, Takeda M, Kashiwagi Y,
Okochi M, Kurumadani T, Sekiyama A, Kanayama G, Hariguchi S and
Nishimura T: Cell-cycle-dependent abnormal calcium response in
fibroblasts from patients with familial Alzheimer's disease.
Dementia. 6:9–16. 1995.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Peterson C, Ratan RR, Shelanski ML and
Goldman JE: Altered response of fibroblasts from aged and Alzheimer
donors to drugs that elevate cytosolic free calcium. Neurobiol
Aging. 9:261–266. 1988.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Cavallucci V, Ferraina C and D'Amelio M:
Key role of mitochondria in Alzheimer's disease synaptic
dysfunction. Curr Pharm Des. 19:6440–6450. 2013.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Perez MJ, Ponce DP, Aranguiz A, Behrens MI
and Quintanilla RA: Mitochondrial permeability transition pore
contributes to mitochondrial dysfunction in fibroblasts of patients
with sporadic Alzheimer's disease. Redox Biol. 19:290–300.
2018.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Calvo-Rodriguez M, Hou SS, Snyder AC,
Kharitonova EK, Russ AN, Das S, Fan Z, Muzikansky A, Garcia-Alloza
M, Serrano-Pozo A, et al: Increased mitochondrial calcium levels
associated with neuronal death in a mouse model of Alzheimer's
disease. Nat Commun. 11(2146)2020.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Jadiya P, Kolmetzky DW, Tomar D, Meco AD,
Lombardi AA, Lambert JP, Luongo TS, Ludtmann MH, Praticò D and
Elrod JW: Impaired mitochondrial calcium efflux contributes to
disease progression in models of Alzheimer's disease. Nat Commun.
10(3885)2019.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Calvo-Rodriguez M and Bacskai BJ: High
mitochondrial calcium levels precede neuronal death in vivo in
Alzheimer's disease. Cell Stress. 4:187–190. 2020.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Ferreiro E, Oliveira CR and Pereira CMF:
The release of calcium from the endoplasmic reticulum induced by
amyloid-beta and prion peptides activates the mitochondrial
apoptotic pathway. Neurobiol Dis. 30:331–342. 2008.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Nikseresht Z, Ahangar N, Badrikoohi M and
Babaei P: Synergistic enhancing-memory effect of D-serine and
RU360, a mitochondrial calcium uniporter blocker in rat model of
Alzheimer's disease. Behav Brain Res. 409(113307)2021.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Hengartner MO: The biochemistry of
apoptosis. Nature. 407:770–776. 2000.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Calvo-Rodriguez M, Hernando-Perez E, Nuñez
L and Villalobos C: Amyloid β oligomers increase ER-mitochondria Ca
2+ cross talk in young hippocampal neurons and exacerbate
aging-induced intracellular Ca 2+ remodeling. Front Cell Neurosci.
13(22)2019.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Singh SK, Srivastav S, Castellani RJ,
Plascencia-Villa G and Perry G: Neuroprotective and antioxidant
effect of ginkgo biloba extract against ad and other neurological
disorders. Neurotherapeutics. 16:666–674. 2019.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Shi C, Liu J, Wu F and Yew DT: Ginkgo
biloba extract in Alzheimer's disease: From action mechanisms to
medical practice. Int J Mol Sci. 11:107–123. 2010.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Nowak A, Kojder K, Zielonka-Brzezicka J,
Wróbel J, Bosiacki M, Fabiańska M, Wróbel M, Sołek-Pastuszka J and
Klimowicz A: The use of ginkgo biloba L. as a neuroprotective agent
in the Alzheimer's disease. Front Pharmacol.
12(775034)2021.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Feng Z, Sun Q, Chen W, Bai Y, Hu D and Xie
X: The neuroprotective mechanisms of ginkgolides and bilobalide in
cerebral ischemic injury: A literature review. Mol Med.
25(57)2019.PubMed/NCBI View Article : Google Scholar
|
