Open Access

Possible association between Guillain‑Barré syndrome and SARS‑CoV‑2 infection in children: A case report and literature review

  • Authors:
    • Ilaria Mussinatto
    • Chiara Benevenuta
    • Anna Caci
    • Mario M. Calvo
    • Maria Impastato
    • Massimo Barra
    • Egidio Genovese
    • Fabio Timeus
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  • Published online on: May 23, 2022     https://doi.org/10.3892/etm.2022.11389
  • Article Number: 462
  • Copyright: © Mussinatto et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection have been reported in adults and in children, varying from mild to more debilitant symptoms, including fatigue, headache and dizziness. A series of studies have revealed a possible association between Guillain‑Barré syndrome (GBS), the most common cause of acute flaccid paralysis at all ages, and SARS‑CoV‑2 infection. Case reports of novel coronavirus disease 2019 (COVID‑19)‑associated GBS mainly include adult patients, while only a few pediatric cases have been reported. The present study describes a case of GBS in an Italian 9‑year‑old girl with previous SARS‑CoV‑2 infection as a possible trigger, and also conducts a literature review on pediatric COVID‑19‑associated GBS cases.
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July-2022
Volume 24 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Mussinatto I, Benevenuta C, Caci A, Calvo MM, Impastato M, Barra M, Genovese E and Timeus F: Possible association between Guillain‑Barré syndrome and SARS‑CoV‑2 infection in children: A case report and literature review. Exp Ther Med 24: 462, 2022
APA
Mussinatto, I., Benevenuta, C., Caci, A., Calvo, M.M., Impastato, M., Barra, M. ... Timeus, F. (2022). Possible association between Guillain‑Barré syndrome and SARS‑CoV‑2 infection in children: A case report and literature review. Experimental and Therapeutic Medicine, 24, 462. https://doi.org/10.3892/etm.2022.11389
MLA
Mussinatto, I., Benevenuta, C., Caci, A., Calvo, M. M., Impastato, M., Barra, M., Genovese, E., Timeus, F."Possible association between Guillain‑Barré syndrome and SARS‑CoV‑2 infection in children: A case report and literature review". Experimental and Therapeutic Medicine 24.1 (2022): 462.
Chicago
Mussinatto, I., Benevenuta, C., Caci, A., Calvo, M. M., Impastato, M., Barra, M., Genovese, E., Timeus, F."Possible association between Guillain‑Barré syndrome and SARS‑CoV‑2 infection in children: A case report and literature review". Experimental and Therapeutic Medicine 24, no. 1 (2022): 462. https://doi.org/10.3892/etm.2022.11389