Safely completed radiotherapy in a patient with breast cancer and right axillary vein approach cardiac pacemaker implantation: A case report

Wang,Yunjuan; Zhao,Jianling; He,Yinbo; Luo,Caiyi; Sun,Yu; Zhou,Li; Xie,Li

doi:10.3892/etm.2022.11716

Safely completed radiotherapy in a patient with breast cancer and right axillary vein approach cardiac pacemaker implantation: A case report

Authors:
- Yunjuan Wang
- Jianling Zhao
- Yinbo He
- Caiyi Luo
- Yu Sun
- Li Zhou
- Li Xie
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Affiliations: Department of Radiology Oncology, Cancer Center, West China Hospital of Sichuan University, Chengdu, Sichuan 610044, P.R. China, Head and Neck Oncology Ward, Cancer Center, West China Hospital of Sichuan University, Chengdu, Sichuan 610044, P.R. China
Published online on: November 21, 2022 https://doi.org/10.3892/etm.2022.11716
Article Number: 17
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Pacemaker implantation is becoming increasingly common in patients with breast cancer. Comprehensive treatment options, such as surgery, chemotherapy, radiation therapy, targeted therapy and immunotherapy, have greatly improved the prognosis of patients with breast cancer. In particular, radiotherapy is an important means of comprehensive breast cancer treatment that can reduce recurrence and prolong survival in high‑risk patients who underwent mastectomy. The pacemaker electrical pulse generator is typically implanted subcutaneously in the left subclavian area above the pectoral muscle through the subclavian vein. The present report implemented a new method of ‘temporary pacemaker electrode and permanent artificial pacemaker placement’ through the right axillary vein in a patient with breast cancer. An electrical pulse generator was placed in the right subcutaneous subclavian tissue. The pacemaker was placed under the right clavicle, and the pacemaker was included as organ at risk (OAR). Dose of planning organ at risk volume (PRV) with additional 6 mm margin to the pacemaker was limited during radiotherapy planning design. This patient with breast cancer, who was also complicated with other underlying comorbidities (such as atrial fibrillation, coronary atherosclerosis, cardiac insufficiency, hypertension, type 2 diabetes mellitus) and implanted with a cardiac pacemaker, was treated with safe (means that the patient has not developed heart disease because of the pacemaker problem) and effective (tumor can be effectively controlled under the condition that the pacemaker does not malfunction) radiotherapy. At present, the patient has successfully completed radiation therapy for breast cancer with no recurrence or metastasis. To the best of our knowledge, the present report is the first to document this application, demonstrating the treatment of a patient with breast cancer and cardiac pacemaker implantation, which is worthy of further study and continuous improvement in clinical practice.

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