Optic neuropathy associated with acute pancreatitis: A case report

Chylova,Hana; Dubska,Zora; Kyncl,Martin; Fus,Martin; Lešták,Ján

doi:10.3892/etm.2022.11757

January-2023 Volume 25 Issue 1

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January-2023 Volume 25 Issue 1

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Case Report Open Access

Optic neuropathy associated with acute pancreatitis: A case report

Authors:
- Hana Chylova
- Zora Dubska
- Martin Kyncl
- Martin Fus
- Ján Lešták
View Affiliations / Copyright

Affiliations: Department of Natural Sciences, Faculty of Biomedical Engineering, Czech Technical University in Prague, 27201 Kladno, Czech Republic, Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 12108 Prague, Czech Republic

Copyright: © Chylova et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 58
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Published online on: December 8, 2022

https://doi.org/10.3892/etm.2022.11757
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Abstract

The present article describes a case of a 24‑year‑old patient who suffered from acute pancreatitis. The patient simultaneously developed visual acuity loss and changes in the visual field. When examined, the finding was physiological, including the fundoscopy. Neither fluorescein angiography or optical coherence tomography demonstrated any retinal abnormalities; electroretinography was physiological as well. The visual evoked potentials (VEP) showed abnormalities in amplitudes. Patient's visual field was reduced to 40˚. The follow‑up examination 13 months after the first symptoms proved a progression of changes in the visual field and prolonged latency of P100 peak in VEP. The retinal nerve fibre layer stayed unchanged, but the vessel density on the optic nerve head decreased. Magnetic resonance brain imaging showed non‑specific subcortical and paraventricular focuses in the white matter of both hemispheres. There were no other abnormalities detected by magnetic resonance imaging. Neurological examination was normal. In conclusion, the present study verified this decrease of visual functions as a lesion in the visual pathway using VEP, which was also confirmed by magnetic resonance brain imaging.

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1	Purtscher O: Angiopathia retinae traumatica. Lymphorrhagien des Augengrundes. Albrecht von Graefe Arch Ophth. 82:347–371. 1912.
2	Behrens-Baumann W, Scheurer G and Schroer H: Pathogenesis of Purtscher's retinopathy. An experimental study. Graefes Arch Clin Exp Ophthalmol. 230:286–291. 1992.PubMed/NCBI View Article : Google Scholar
3	Tripathy K and Patel BC: Purtscher retinopathy. In: StatPearls [Internet]. StatPearls Publishing, Treasure Island, FL, 2022.
4	Suárez Crespo JF, de Teresa Galván FJ, Sánchez Rico C, González Galilea A, Pinel Julián LM, Espinosa Aguilar MD and López de Hierro Ruiz M: Purtscher's retinopathy and acute alcoholic pancreatitis. Rev Esp Enferm Dig. 885:513–515. 1996.PubMed/NCBI(In Spanish).
5	Sharma AG, Kazim NA, Eliott D, Houghton O and Abrams GW: Purtscher's retinopathy that occurred 6 months before acute pancreatitis. Am J Ophthalmol. 141:205–207. 2006.PubMed/NCBI View Article : Google Scholar
6	Lešták J, Nutterová E, Pitrová Š, Krejčová H, Bartošová L and Forgáčová V: High tension versus normal tension glaucoma. A comparison of structural and functional examinations. J Clinic Exp Ophthalmol S. (5)2012.
7	Campo SM, Gasparri V, Catarinelli G and Sepe M: Acute pancreatitis with Purtscher's retinopathy: Case report and review of the literature. Dig Liver Dis. 32:729–732. 2000.PubMed/NCBI View Article : Google Scholar
8	Hayreh SS: Posterior ischaemic optic neuropathy: Clinical features, pathogenesis, and management. Eye (Lond). 18:1188–1206. 2004.PubMed/NCBI View Article : Google Scholar
9	Oh DJ, Chhadva P, Kanu LN, Liu CY and Macintosh PW: Sudden-onset blindness from a spontaneous carotid-cavernous fistula with secondary central retinal artery occlusion and posterior ischemic optic neuropathy. Neuroophthalmology. 43:107–113. 2018.PubMed/NCBI View Article : Google Scholar
10	Lee AG, Brazis PW and Miller NR: Posterior ischemic optic neuropathy associated with migraine. Headache. 36:506–510. 1996.PubMed/NCBI View Article : Google Scholar
11	Foroozan R, Marx DP and Evans RW: Posterior ischemic optic neuropathy associated with migraine. Headache. 48:1135–1139. 2008.PubMed/NCBI View Article : Google Scholar
12	Buono LM, Foroozan R, Savino PJ, Danesh-Meyer HV and Stanescu D: Posterior ischemic optic neuropathy after hemodialysis. Ophthalmology. 110:1216–1218. 2003.PubMed/NCBI View Article : Google Scholar
13	Buono LM and Foroozan R: Perioperative posterior ischemic optic neuropathy: Review of the literature. Surv Ophthalmol. 50:15–26. 2005.PubMed/NCBI View Article : Google Scholar
14	Weber ED, Colyer MH, Lesser RL and Subramanian PS: Posterior ischemic optic neuropathy after minimally invasive prostatectomy. J Neuroophthalmol. 27:285–287. 2007.PubMed/NCBI View Article : Google Scholar
15	Eli IM, Kim RB, Kilburg C, Pecha TJ, Couldwell WT and Menacho ST: Postoperative posterior ischemic optic neuropathy after left far-lateral craniectomy for resection of craniocervical meningioma. World Neurosurg. 114:339–343. 2018.PubMed/NCBI View Article : Google Scholar
16	Levinson B and Reddy S: Posterior ischemic optic neuropathy after extensive spine surgery: A case report and review of the literature. AANA J. 87:37–42. 2019.PubMed/NCBI
17	Oliver JD, Kobets AJ, Judy BF and Cohen AR: Posterior ischemic optic neuropathy following supine craniotomy for epidural abscess in a child. Childs Nerv Syst. 37:2657–2660. 2021.PubMed/NCBI View Article : Google Scholar
18	Hayreh SS: Ischemic optic neuropathy. Prog Retin Eye Res. 28:34–62. 2009.PubMed/NCBI View Article : Google Scholar
19	Maramattom BV, Sundar S, Thomas D and Panikar D: Postoperative posterior ischemic optic neuropathy (PION) following right pterional meningioma surgery. Ann Indian Acad Neurol. 19:374–376. 2016.PubMed/NCBI View Article : Google Scholar

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Optic neuropathy associated with acute pancreatitis: A case report

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Abstract

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