Wiltse transforaminal thoracic interbody fusion approach for the treatment of single‑segment thoracic spinal tuberculosis in elderly patients with osteoporosis: A retrospective study of 20 cases

Zeng,Hao; Liao,Simi; Liang,Yingfang; Moro,Abu; Chen,Guanghui; Qin,Hongyu

doi:10.3892/etm.2023.11834

March-2023 Volume 25 Issue 3

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March-2023 Volume 25 Issue 3

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Article Open Access

Wiltse transforaminal thoracic interbody fusion approach for the treatment of single‑segment thoracic spinal tuberculosis in elderly patients with osteoporosis: A retrospective study of 20 cases

Authors:
- Hao Zeng
- Simi Liao
- Yingfang Liang
- Abu Moro
- Guanghui Chen
- Hongyu Qin
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Affiliations: Department of Spine and Osteopathy Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530000, P.R. China, Department of Spine and Osteopathy Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530000, P.R. China, Department of Comprehensive Internal Medicine, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530000, P.R. China, Department of Traumatology and Orthopedics of Traditional Chinese Medicine, First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, Guangxi 530000, P.R. China

Copyright: © Zeng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 135
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Published online on: February 13, 2023

https://doi.org/10.3892/etm.2023.11834
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Abstract

The aim of the present study was to investigate the clinical feasibility and efficacy of the Wiltse approach and TTIF in elderly patients with single‑segment thoracic tuberculosis (SSTTB) complicated with osteoporosis and neurological dysfunction. Between January 2017 and January 2019, 20 elderly patients underwent the Wiltse TTIF approach at a single hospital. The follow‑up time of these patients was 37.15±7.37 months (range, 24‑48 months). The preoperative kyphosis angle was 35.41±6.71˚. The degree of neurological deficit in each patient was assessed using the Frankel spinal cord injury classification. In addition, TB activity was monitored using erythrocyte sedimentation rate and C‑reactive protein levels, and the degree of osteoporosis was evaluated using femoral neck bone mineral density T‑scores. The 20 patients with SSTTB were completely cured without recurrence. The postoperative kyphotic angle was 8.80±0.79˚, without significant loss of correction at the final follow‑up. Bone graft fusion was observed within 6‑9 months, with all patients reporting relief of their back pain. The neurological condition of all the patients improved postoperatively. The present study indicates that Wiltse TTIF surgery combined with anti‑TB chemotherapy has satisfactory efficacy in elderly patients with SSTTB complicated by osteoporosis and neurological impairment.

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