|
1
|
Gianferante DM, Mirabello L and Savage SA:
Germline and somatic genetics of osteosarcoma-connecting aetiology,
biology and therapy. Nat Rev Endocrinol. 13:480–491.
2017.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Whelan JS and Davis LE: Osteosarcoma,
chondrosarcoma, and chordoma. J Clin Oncol. 36:188–193.
2018.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Zheng Y, Wang G, Chen R, Hua Y and Cai Z:
Mesenchymal stem cells in the osteosarcoma microenvironment: Their
biological properties, influence on tumor growth, and therapeutic
implications. Stem Cell Res Ther. 9(22)2018.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Anderson ME: Update on survival in
osteosarcoma. Orthop Clin North Am. 47:283–292. 2016.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Brewer HB Jr, Shulman R, Herbert P, Ronan
R and Wehrly K: The complete amino acid sequence of alanine
apolipoprotein (apoC-3), and apolipoprotein from human plasma very
low density lipoproteins. J Biol Chem. 249:4975–4984.
1974.PubMed/NCBI
|
|
6
|
Fuior EV and Gafencu AV: Apolipoprotein
C1: Its pleiotropic effects in lipid metabolism and beyond. Int J
Mol Sci. 20(5939)2019.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Ren H, Chen Z, Yang L, Xiong W, Yang H, Xu
K, Zhai E, Ding L, He Y and Song X: Apolipoprotein C1 (APOC1)
promotes tumor progression via MAPK signaling pathways in
colorectal cancer. Cancer Manag Res. 11:4917–4930. 2019.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Shi X, Wang J, Dai S, Qin L, Zhou J and
Chen Y: Apolipoprotein C1 (APOC1): A novel diagnostic and
prognostic biomarker for cervical cancer. Onco Targets Ther.
13:12881–12891. 2020.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Guo Q, Liu XL, Jiang N, Zhang WJ, Guo SW,
Yang H, Ji YM, Zhou J, Guo JL, Zhang J and Liu HS: Decreased APOC1
expression inhibited cancer progression and was associated with
better prognosis and immune microenvironment in esophageal cancer.
Am J Cancer Res. 12:4904–4929. 2022.PubMed/NCBI
|
|
10
|
Liu J, Wu S, Xie X, Wang Z and Lei Q:
Identification of potential crucial genes and key pathways in
osteosarcoma. Hereditas. 157(29)2020.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Robinson AJ, Kunji ER and Gross A:
Mitochondrial carrier homolog 2 (MTCH2): The recruitment and
evolution of a mitochondrial carrier protein to a critical player
in apoptosis. Exp Cell Res. 318:1316–1323. 2012.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Fu D, Liu S, Liu J, Chen W, Long X, Chen
X, Zhou Y, Zheng Y and Huang S: iTRAQ-based proteomic analysis of
the molecular mechanisms and downstream effects of fatty acid
synthase in osteosarcoma cells. J Clin Lab Anal.
35(e23653)2021.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Yuan Q, Yang W, Zhang S, Li T, Zuo M, Zhou
X, Li J, Li M, Xia X, Chen M and Liu Y: Inhibition of mitochondrial
carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances
sensitivity to temozolomide in malignant glioma. Mol Med.
27(7)2021.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Buzaglo-Azriel L, Kuperman Y, Tsoory M,
Zaltsman Y, Shachnai L, Zaidman SL, Bassat E, Michailovici I,
Sarver A, Tzahor E, et al: Loss of muscle MTCH2 increases
whole-body energy utilization and protects from diet-induced
obesity. Cell Rep. 14:1602–1610. 2016.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Vander Heiden MG, Cantley LC and Thompson
CB: Understanding the Warburg effect: The metabolic requirements of
cell proliferation. Science. 324:1029–1033. 2009.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Warburg O, Wind F and Negelein E: The
metabolism of tumors in the body. J Gen Physiol. 8:519–530.
1927.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Baltazar F, Afonso J, Costa M and Granja
S: Lactate beyond a waste metabolite: Metabolic affairs and
signaling in malignancy. Front Oncol. 10(231)2020.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Schwartz L, Supuran CT and Alfarouk KO:
The Warburg effect and the hallmarks of cancer. Anticancer Agents
Med Chem. 17:164–170. 2017.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Zhu R, Li X and Ma Y: miR-23b-3p
suppressing PGC1α promotes proliferation through reprogramming
metabolism in osteosarcoma. Cell Death Dis. 10(381)2019.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Oughtred R, Stark C, Breitkreutz BJ, Rust
J, Boucher L, Chang C, Kolas N, O'Donnell L, Leung G, McAdam R, et
al: The BioGRID interaction database: 2019 update. Nucleic Acids
Res. 47:D529–D541. 2019.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Szklarczyk D, Gable AL, Lyon D, Junge A,
Wyder S, Huerta-Cepas J, Simonovic M, Doncheva NT, Morris JH, Bork
P, et al: STRING v11: Protein-protein association networks with
increased coverage, supporting functional discovery in genome-wide
experimental datasets. Nucleic Acids Res. 47:D607–D613.
2019.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Livak KJ and Schmittgen TD: . Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Kobliakov VA: The mechanisms of regulation
of aerobic glycolysis (Warburg effect) by oncoproteins in
carcinogenesis. Biochemistry (Mosc). 84:1117–1128. 2019.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Abbaszadeh Z, Çeşmeli S and Biray Avcı Ç:
Crucial players in glycolysis: Cancer progress. Gene.
726(144158)2020.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Sica V, Bravo-San Pedro JM, Stoll G and
Kroemer G: Oxidative phosphorylation as a potential therapeutic
target for cancer therapy. Int J Cancer. 146:10–17. 2020.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Ottaviani G and Jaffe N: The epidemiology
of osteosarcoma. Cancer Treat Res. 152:3–13. 2009.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Jong MC, Hofker MH and Havekes LM: Role of
ApoCs in lipoprotein metabolism: Functional differences between
ApoC1, ApoC2, and ApoC3. Arterioscler Thromb Vasc Biol. 19:472–484.
1999.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Jong MC, Dahlmans VE, van Gorp PJ, van
Dijk KW, Breuer ML, Hofker MH and Havekes LM: In the absence of the
low density lipoprotein receptor, human apolipoprotein C1
overexpression in transgenic mice inhibits the hepatic uptake of
very low density lipoproteins via a receptor-associated
protein-sensitive pathway. J Clin Invest. 98:2259–2267.
1996.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Muurling M, van den Hoek AM, Mensink RP,
Pijl H, Romijn JA, Havekes LM and Voshol PJ: Overexpression of
APOC1 in obob mice leads to hepatic steatosis and severe hepatic
insulin resistance. J Lipid Res. 45:9–16. 2004.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Poirier J, Hess M, May PC and Finch CE:
Cloning of hippocampal poly(A) RNA sequences that increase after
entorhinal cortex lesion in adult rat. Brain Res Mol Brain Res.
9:191–195. 1991.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Leduc V, Jasmin-Bélanger S and Poirier J:
APOE and cholesterol homeostasis in Alzheimer's disease. Trends Mol
Med. 16:469–477. 2010.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Li YL, Wu LW, Zeng LH, Zhang ZY, Wang W,
Zhang C and Lin NM: ApoC1 promotes the metastasis of clear cell
renal cell carcinoma via activation of STAT3. Oncogene.
39:6203–6217. 2020.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Zhang H, Wang Y, Liu C, Li W, Zhou F, Wang
X and Zheng J: The Apolipoprotein C1 is involved in breast cancer
progression via EMT and MAPK/JNK pathway. Pathol Res Pract.
229(153746)2022.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Takano S, Yoshitomi H, Togawa A, Sogawa K,
Shida T, Kimura F, Shimizu H, Tomonaga T, Nomura F and Miyazaki M:
Apolipoprotein C-1 maintains cell survival by preventing from
apoptosis in pancreatic cancer cells. Oncogene. 27:2810–2822.
2008.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Wang HJ, Ma YX, Wang AH, Jiang YS and
Jiang XZ: Expression of apolipoprotein C1 in clear cell renal cell
carcinoma: An oncogenic gene and a prognostic marker. Kaohsiung J
Med Sci. 37:419–426. 2021.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Trougakos IP, So A, Jansen B, Gleave ME
and Gonos ES: Silencing expression of the clusterin/apolipoprotein
j gene in human cancer cells using small interfering RNA induces
spontaneous apoptosis, reduced growth ability, and cell
sensitization to genotoxic and oxidative stress. Cancer Res.
64:1834–1842. 2004.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Delbridge AR, Grabow S, Strasser A and
Vaux DL: Thirty years of BCL-2: Translating cell death discoveries
into novel cancer therapies. Nat Rev Cancer. 16:99–109.
2016.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Burlacu A: Regulation of apoptosis by
Bcl-2 family proteins. J Cell Mol Med. 7:249–257. 2003.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Lowe SW and Lin AW: Apoptosis in cancer.
Carcinogenesis. 21:485–495. 2000.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Hu W and Xiao Z: Formononetin induces
apoptosis of human osteosarcoma cell line U2OS by regulating the
expression of Bcl-2, Bax and MiR-375 in vitro and in vivo. Cell
Physiol Biochem. 37:933–939. 2015.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Zhao S, Zhang Y, Lu X, Ding H, Han B, Song
X, Miao H, Cui X, Wei S, Liu W, et al: CDC20 regulates the cell
proliferation and radiosensitivity of P53 mutant HCC cells through
the Bcl-2/Bax pathway. Int J Biol Sci. 17:3608–3621.
2021.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Huang LL, Wang Z, Cao CJ, Ke ZF, Wang F,
Wang R, Luo CQ, Lu X and Wang LT: AEG-1 associates with metastasis
in papillary thyroid cancer through upregulation of MMP2/9. Int J
Oncol. 51:812–822. 2017.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Zaltsman Y, Shachnai L, Yivgi-Ohana N,
Schwarz M, Maryanovich M, Houtkooper RH, Vaz FM, De Leonardis F,
Fiermonte G, Palmieri F, et al: MTCH2/MIMP is a major facilitator
of tBID recruitment to mitochondria. Nat Cell Biol. 12:553–562.
2010.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Grinberg M, Schwarz M, Zaltsman Y, Eini T,
Niv H, Pietrokovski S and Gross A: Mitochondrial carrier homolog 2
is a target of tBID in cells signaled to die by tumor necrosis
factor alpha. Mol Cell Biol. 25:4579–4590. 2005.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Khan DH, Mullokandov M, Wu Y, Voisin V,
Gronda M, Hurren R, Wang X, MacLean N, Jeyaraju DV, Jitkova Y, et
al: Mitochondrial carrier homolog 2 is necessary for AML survival.
Blood. 136:81–92. 2020.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Arigoni M, Barutello G, Riccardo F, Ercole
E, Cantarella D, Orso F, Conti L, Lanzardo S, Taverna D, Merighi I,
et al: miR-135b coordinates progression of ErbB2-driven mammary
carcinomas through suppression of MID1 and MTCH2. Am J Pathol.
182:2058–2070. 2013.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Liu L, Chai L, Ran J, Yang Y and Zhang L:
BAI1 acts as a tumor suppressor in lung cancer A549 cells by
inducing metabolic reprogramming via the SCD1/HMGCR module.
Carcinogenesis. 41:1724–1734. 2020.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Wu Z, Wu J, Zhao Q, Fu S and Jin J:
Emerging roles of aerobic glycolysis in breast cancer. Clin Transl
Oncol. 22:631–646. 2020.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Li L, Ji Y, Zhang L, Cai H, Ji Z, Gu L and
Yang S: Wogonin inhibits the growth of HT144 melanoma via
regulating hedgehog signaling-mediated inflammation and glycolysis.
Int Immunopharmacol. 101(108222)2021.PubMed/NCBI View Article : Google Scholar
|
|
50
|
Sottnik JL, Lori JC, Rose BJ and Thamm DH:
Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic
phenotype in vitro and in vivo. Clin Exp Metastasis. 28:865–875.
2011.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Shen S, Yao T, Xu Y, Zhang D, Fan S and Ma
J: CircECE1 activates energy metabolism in osteosarcoma by
stabilizing c-Myc. Mol Cancer. 19(151)2020.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Zhao SJ, Shen YF, Li Q, He YJ, Zhang YK,
Hu LP, Jiang YQ, Xu NW, Wang YJ, Li J, et al: SLIT2/ROBO1 axis
contributes to the Warburg effect in osteosarcoma through
activation of SRC/ERK/c-MYC/PFKFB2 pathway. Cell Death Dis.
9(390)2018.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Maryanovich M, Zaltsman Y, Ruggiero A,
Goldman A, Shachnai L, Zaidman SL, Porat Z, Golan K, Lapidot T and
Gross A: An MTCH2 pathway repressing mitochondria metabolism
regulates haematopoietic stem cell fate. Nat Commun.
6(7901)2015.PubMed/NCBI View Article : Google Scholar
|
