A solitary rectal juvenile polyp with chicken skin‑like changes in the surrounding mucosa in an adult: A case report

Sun,Xue-Guo; Han,Yue; Song,Ming Quan; Shan,Ti-Dong

doi:10.3892/etm.2023.11884

A solitary rectal juvenile polyp with chicken skin‑like changes in the surrounding mucosa in an adult: A case report

Authors:
- Xue-Guo Sun
- Yue Han
- Ming Quan Song
- Ti-Dong Shan
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Affiliations: Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 262000, P.R. China
Published online on: March 13, 2023 https://doi.org/10.3892/etm.2023.11884
Article Number: 185
Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The majority of colorectal polyps in adults are adenomatous polyps, while hamartoma polyps are rare. Juvenile polyps are the most common type of polyp in children; however, they are rare in adults. Fecal calprotectin (FCP) is commonly elevated in inflammatory bowel disease and is rarely studied in juvenile rectal polyps. Reports of elevated FCP in solitary juvenile rectal polyps of adults are rare. A 57‑year‑old female was admitted to The Affiliated Hospital of Qingdao University (Qingdao, China) for treatment due to intermittent stool with mucus and blood. Colonoscopy revealed a solitary polyp in the rectum with a diameter of ~2.0 cm, a short and wide subpedicle, with congested and swollen mucosa on the surface and chicken skin‑like changes in the surrounding mucosa. The patient had no family history of colorectal polyps or cancer. Endoscopic submucosal dissection was used to remove the polyp. Histopathological examination indicated that the polyp was a juvenile polyp and no signs of malignancy were found. The present case report describes details on this case of an adult patient with a solitary juvenile rectal polyp with chicken skin‑like changes in the surrounding mucosa and high FCP.

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1	Leonard NB and Bronner MP: Giant gastric folds in juvenile polyposis. Case Rep Gastroenterol. 15:985–993. 2021.PubMed/NCBI View Article : Google Scholar
2	Brosens LA, van Hattem A, Hylind LM, Iacobuzio-Donahue C, Romans KE, Axilbund J, Cruz-Correa M, Tersmette AC, Offerhaus GJ and Giardiello FM: Risk of colorectal cancer in juvenile polyposis. Gut. 56:965–967. 2007.PubMed/NCBI View Article : Google Scholar
3	Calva-Cerqueira D, Chinnathambi S, Pechman B, Bair J, Larsen-Haidle J and Howe JR: The rate of germline mutations and large deletions of SMAD4 and BMPR1A in juvenile polyposis. Clin Genet. 75:79–85. 2009.PubMed/NCBI View Article : Google Scholar
4	Gao XH, Li J, Zhao ZY, Xu XD, Du YQ, Yan HL, Liu LJ, Bai CG and Zhang W: Juvenile polyposis syndrome might be misdiagnosed as familial adenomatous polyposis: A case report and literature review. BMC Gastroenterol. 20(167)2020.PubMed/NCBI View Article : Google Scholar
5	Aretz S, Stienen D, Uhlhaas S, Stolte M, Entius MM, Loff S, Back W, Kaufmann A, Keller KM, Blaas SH, et al: High proportion of large genomic deletions and a genotype phenotype update in 80 unrelated families with juvenile polyposis syndrome. J Med Genet. 44:702–709. 2007.PubMed/NCBI View Article : Google Scholar
6	Latchford AR, Neale K, Phillips RK and Clark SK: Juvenile polyposis syndrome: A study of genotype, phenotype, and long-term outcome. Dis Colon Rectum. 55:1038–1043. 2012.PubMed/NCBI View Article : Google Scholar
7	Patel R and Hyer W: Practical management of polyposis syndromes. Frontline Gastroenterol. 10:379–387. 2019.PubMed/NCBI View Article : Google Scholar
8	Gammon A, Jasperson K, Kohlmann W and Burt RW: Hamartomatous polyposis syndromes. Best Pract Res Clin Gastroenterol. 23:219–231. 2009.PubMed/NCBI View Article : Google Scholar
9	Liu S, Ma Y, You W, Li J, Li JN and Qian JM: Hamartomatous polyposis syndrome associated malignancies: Risk, pathogenesis and endoscopic surveillance. J Dig Dis. 22:444–451. 2021.PubMed/NCBI View Article : Google Scholar
10	Chen YW, Tu JF, Shen WJ, Chen WY and Dong J: Diagnosis and management of a solitary colorectal juvenile polyp in an adult during follow-up for ulcerative colitis: A case report. World J Gastroenterol. 26:877–882. 2020.PubMed/NCBI View Article : Google Scholar
11	Zheng Z, Yin J, Li Z, Ye Y, Wei B, Wang X, Tian Y, Li M, Zhang Q, Zeng N, et al: Protocol for expanded indications of endoscopic submucosal dissection for early gastric cancer in China: A multicenter, ambispective, observational, open-cohort study. BMC Cancer. 20(801)2020.PubMed/NCBI View Article : Google Scholar
12	Zbuk KM and Eng C: Hamartomatous polyposis syndromes. Nat Clin Pract Gastroenterol Hepatol. 4:492–502. 2007.PubMed/NCBI View Article : Google Scholar
13	Dickey W, Alderdice J and McConnell B: Dysplastic change in the solitary juvenile polyp. Endoscopy. 28(641)1996.PubMed/NCBI View Article : Google Scholar
14	Jelsig AM, Ousager LB, Brusgaard K and Qvist N: Juvenile polyps in Denmark from 1995 to 2014. Dis Colon Rectum. 59:751–757. 2016.PubMed/NCBI View Article : Google Scholar
15	Chow E and Macrae F: A review of juvenile polyposis syndrome. J Gastroenterol Hepatol. 20:1634–1640. 2005.PubMed/NCBI View Article : Google Scholar
16	Brosens LA, Langeveld D, Van Hattem WA, Giardiello FM and Offerhaus GJ: Juvenile polyposis syndrome. World J Gastroenterol. 17:4839–4844. 2011.PubMed/NCBI View Article : Google Scholar
17	Hirotani A, Sakai E, Nakajima A, Kawana K and Nagase H: Endoscopic findings of atypical juvenile colonic polyps. Gastrointest Endosc. 83:476–477. 2016.PubMed/NCBI View Article : Google Scholar
18	Chung EJ, Lee JY, Choe J, Chang HS, Kim J, Yang DH, Ye BD, Byeon JS, Kim KJ, Yang SK, et al: Colonic chicken skin mucosa is an independent endoscopic predictor of advanced colorectal adenoma. Intest Res. 13:318–325. 2015.PubMed/NCBI View Article : Google Scholar
19	Adamiec C, Folwarski M, Dubowik M, Adrych K, Kaźmierczak-Siedlecka K and Makarewicz W: Kudo's pit pattern classification for in vivo optical diagnosis and discrimination of advanced colorectal polyps. Eur Rev Med Pharmacol Sci. 26:2832–2839. 2022.PubMed/NCBI View Article : Google Scholar
20	Hijos-Mallada G, Velamazán R, Marti R, Chueca E, Arechavaleta S, Lué A, Gomollón F, Lanas A and Sostres C: A patient self-made point-of-care fecal test improves diagnostic accuracy compared with fecal calprotectin alone in inflammatory bowel disease patients. Diagnostics (Basel). 11(2323)2021.PubMed/NCBI View Article : Google Scholar
21	Hodgson-Parnell L, Spence O and Chapple K: Solitary juvenile polyp as a cause of elevated faecal calprotectin in an adult. BMJ Case Rep. 2018(bcr2018224770)2018.PubMed/NCBI View Article : Google Scholar