|
1
|
Ferrari SL and Rizzoli R: Gene variants
for osteoporosis and their pleiotropic effects in aging. Mol
Aspects Med. 26:145–167. 2005.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Li H, Hastings MH, Rhee J, Trager LE, Roh
JD and Rosenzweig A: Targeting age-related pathways in heart
failure. Circ Res. 126:533–551. 2020.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Roberts S, Colombier P, Sowman A, Mennan
C, Rölfing JH, Guicheux J and Edwards JR: Ageing in the
musculoskeletal system. Acta Orthop. 87 (Suppl 363):15–25.
2016.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Heuberger RA: The frailty syndrome: A
comprehensive review. J Nutr Gerontol Geriatr. 30:315–368.
2011.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Cooper C, Dere W, Evans W, Kanis JA,
Rizzoli R, Sayer AA, Sieber CC, Kaufman JM, Abellan van Kan G,
Boonen S, et al: Frailty and sarcopenia: Definitions and outcome
parameters. Osteoporos Int. 23:1839–1848. 2012.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Loh KM, Chen A, Koh PW, Deng TZ, Sinha R,
Tsai JM, Barkal AA, Shen KY, Jain R, Morganti RM, et al: Mapping
the pairwise choices leading from pluripotency to human bone,
heart, and other mesoderm cell types. Cell. 166:451–467.
2016.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Hamrick MW: Increased bone mineral density
in the femora of GDF8 knockout mice. Anat Rec A Discov Mol Cell
Evol Biol. 272:388–391. 2003.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Pedersen BK and Febbraio MA: Muscles,
exercise and obesity: Skeletal muscle as a secretory organ. Nat Rev
Endocrinol. 8:457–465. 2012.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Herrmann M, Engelke K, Ebert R,
Müller-Deubert S, Rudert M, Ziouti F, Jundt F, Felsenberg D and
Jakob F: Interactions between muscle and bone-where physics meets
biology. Biomolecules. 10(432)2020.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Bonewald L: Use it or lose it to age: A
review of bone and muscle communication. Bone. 120:212–218.
2019.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Kirk B, Al Saedi A and Duque G:
Osteosarcopenia: A case of geroscience. Aging Med (Milton).
2:147–156. 2019.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Di Monaco M, Castiglioni C, Bardesono F,
Milano E and Massazza G: Sarcopenia, osteoporosis and the burden of
prevalent vertebral fractures: A cross-sectional study of 350 women
with hip fracture. Eur J Phys Rehabil Med. 56:184–190.
2020.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Patel HP, Dawson A, Westbury LD, Hasnaoui
G, Syddall HE, Shaw S, Sayer AA, Cooper C and Dennison EM: Muscle
mass, muscle morphology and bone health among community-dwelling
older men: Findings from the hertfordshire sarcopenia study (HSS).
Calcif Tissue Int. 103:35–43. 2018.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Sipilä S, Törmäkangas T, Sillanpää E,
Aukee P, Kujala UM, Kovanen V and Laakkonen EK: Muscle and bone
mass in middle-aged women: Role of menopausal status and physical
activity. J Cachexia Sarcopenia Muscle. 11:698–709. 2020.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Hernlund E, Svedbom A, Ivergård M,
Compston J, Cooper C, Stenmark J, McCloskey EV, Jönsson B and Kanis
JA: Osteoporosis in the European Union: Medical management,
epidemiology and economic burden. A report prepared in
collaboration with the International Osteoporosis Foundation (IOF)
and the European Federation of Pharmaceutical Industry Associations
(EFPIA). Arch Osteoporos. 8(136)2013.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Curtis E, Litwic A, Cooper C and Dennison
E: Determinants of muscle and bone aging. J Cell Physiol.
230:2618–2625. 2015.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Novotny SA, Warren GL and Hamrick MW:
Aging and the muscle-bone relationship. Physiology (Bethesda).
30:8–16. 2015.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Paintin J, Cooper C and Dennison E:
Osteosarcopenia. Br J Hosp Med (Lond). 79:253–258. 2018.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Rosenberg IH: Sarcopenia: Origins and
clinical relevance. J Nutr. 127 (5 Suppl):990S–991S.
1997.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Cruz-Jentoft AJ, Baeyens JP, Bauer JM,
Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y,
Schneider SM, et al: Sarcopenia: European consensus on definition
and diagnosis: Report of the European working group on sarcopenia
in older people. Age Ageing. 39:412–423. 2010.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Anker SD, Morley JE and von Haehling S:
Welcome to the ICD-10 code for sarcopenia. J Cachexia Sarcopenia
Muscle. 7:512–514. 2016.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Petermann-Rocha F, Balntzi V, Gray SR,
Lara J, Ho FK, Pell JP and Celis-Morales C: Global prevalence of
sarcopenia and severe sarcopenia: A systematic review and
meta-analysis. J Cachexia Sarcopenia Muscle. 13:86–99.
2022.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Hong AR and Kim SW: Effects of resistance
exercise on bone health. Endocrinol Metab (Seoul). 33:435–444.
2018.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Chen LK, Liu LK, Woo J, Assantachai P,
Auyeung TW, Bahyah KS, Chou MY, Chen LY, Hsu PS, Krairit O, et al:
Sarcopenia in Asia: Consensus report of the Asian Working Group for
Sarcopenia. J Am Med Dir Assoc. 15:95–101. 2014.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Janssen I, Heymsfield SB and Ross R: Low
relative skeletal muscle mass (sarcopenia) in older persons is
associated with functional impairment and physical disability. J Am
Geriatr Soc. 50:889–896. 2002.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Morley JE: Sarcopenia: Diagnosis and
treatment. J Nutr Health Aging. 12:452–456. 2008.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Bouchard DR, Dionne IJ and Brochu M:
Sarcopenic/obesity and physical capacity in older men and women:
Data from the Nutrition as a Determinant of Successful Aging
(NuAge)-the Quebec longitudinal Study. Obesity (Silver Spring).
17:2082–2088. 2009.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Sjöblom S, Suuronen J, Rikkonen T,
Honkanen R, Kröger H and Sirola J: Relationship between
postmenopausal osteoporosis and the components of clinical
sarcopenia. Maturitas. 75:175–180. 2013.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Kim MK, Baek KH, Song KH, Il Kang M, Park
CY, Lee WY and Oh KW: Vitamin D deficiency is associated with
sarcopenia in older Koreans, regardless of obesity: The Fourth
Korea National Health and Nutrition Examination Surveys (KNHANES
IV) 2009. J Clin Endocrinol Metab. 96:3250–3256. 2011.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Cheng Q, Zhu X, Zhang X, Li H, Du Y, Hong
W, Xue S and Zhu H: A cross-sectional study of loss of muscle mass
corresponding to sarcopenia in healthy Chinese men and women:
Reference values, prevalence, and association with bone mass. J
Bone Miner Metab. 32:78–88. 2014.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Han P, Kang L, Guo Q, Wang J, Zhang W,
Shen S, Wang X, Dong R, Ma Y, Shi Y, et al: Prevalence and factors
associated with sarcopenia in suburb-dwelling older chinese using
the asian working group for sarcopenia definition. J Gerontol A
Biol Sci Med Sci. 71:529–535. 2016.PubMed/NCBI View Article : Google Scholar
|
|
32
|
González Correa CH, Marulanda Mejía F,
Castaño González PA, Vidarte Claros JA and Castiblanco Arroyabe HD:
Bioelectrical impedance analysis and dual x-ray absorptiometry
agreement for skeletal muscle mass index evaluation in sarcopenia
diagnosis. Physiol Meas. 41(064005)2020.PubMed/NCBI View Article : Google Scholar
|
|
33
|
van Baar H, Hulshof PJM, Tieland M and de
Groot CPGM: Bio-impedance analysis for appendicular skeletal muscle
mass assessment in (pre-) frail elderly people. Clin Nutr ESPEN.
10:e147–e153. 2015.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Frontera WR and Ochala J: Skeletal muscle:
A brief review of structure and function. Calcif Tissue Int.
96:183–195. 2015.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Vikberg S, Sörlén N, Brandén L, Johansson
J, Nordström A, Hult A and Nordström P: Effects of resistance
training on functional strength and muscle mass in 70-year-old
individuals with pre-sarcopenia: A randomized controlled trial. J
Am Med Dir Assoc. 20:28–34. 2019.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Liu JC, Dong SS, Shen H, Yang DY, Chen BB,
Ma XY, Peng YR, Xiao HM and Deng HW: Multi-omics research in
sarcopenia: Current progress and future prospects. Ageing Res Rev.
76(101576)2022.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Consensus development conference.
Diagnosis, prophylaxis, and treatment of osteoporosis. Am J Med.
94:646–650. 1993.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Yin X, Zhou C, Li J, Liu R, Shi B, Yuan Q
and Zou S: Autophagy in bone homeostasis and the onset of
osteoporosis. Bone Res. 7(28)2019.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Collins FL, Rios-Arce ND, Schepper JD,
Parameswaran N and McCabe LR: The potential of probiotics as a
therapy for osteoporosis. Microbiol Spectr 5:
10.1128/microbiolspec.BAD-0015-2016, 2017.
|
|
40
|
Das S and Crockett JC: Osteoporosis-a
current view of pharmacological prevention and treatment. Drug Des
Devel Ther. 7:435–448. 2013.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Ensrud KE and Crandall CJ: Osteoporosis.
Ann Intern Med. 167:ITC17–ITC32. 2017.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Anthamatten A and Parish A: Clinical
update on osteoporosis. J Midwifery Womens Health. 64:265–275.
2019.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Marcucci G and Brandi ML: Rare causes of
osteoporosis. Clin Cases Miner Bone Metab. 12:151–156.
2015.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Hurley DL and Khosla S: Update on primary
osteoporosis. Mayo Clin Proc. 72:943–949. 1997.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Stein E and Shane E: Secondary
osteoporosis. Endocrinol Metab Clin North Am. 32:115–34, vii.
2003.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Armas LAG and Recker RR: Pathophysiology
of osteoporosis: New mechanistic insights. Endocrinol Metab Clin
North Am. 41:475–486. 2012.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Amin S, Achenbach SJ, Atkinson EJ, Khosla
S and Melton LJ: Trends in fracture incidence: A population-based
study over 20 years. J Bone Miner Res. 29:581–589. 2014.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Coughlan T and Dockery F: Osteoporosis and
fracture risk in older people. Clin Med (Lond). 14:187–191.
2014.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Gullberg B, Johnell O and Kanis JA:
World-wide projections for hip fracture. Osteoporos Int. 7:407–413.
1997.PubMed/NCBI View Article : Google Scholar
|
|
50
|
Kanis JA, Cooper C, Rizzoli R and
Reginster JY: Scientific Advisory Board of the European Society for
Clinical and Economic Aspects of Osteoporosis (ESCEO) and the
Committees of Scientific Advisors and National Societies of the
International Osteoporosis Foundation (IOF). European guidance for
the diagnosis and management of osteoporosis in postmenopausal
women. Osteoporos Int. 30:3–44. 2019.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Nishizawa Y, Miura M, Ichimura S, Inaba M,
Imanishi Y, Shiraki M, Takada J, Chaki O, Hagino H, Fukunaga M, et
al: Executive summary of the Japan osteoporosis society guide for
the use of bone turnover markers in the diagnosis and treatment of
osteoporosis (2018 Edition). Clin Chim Acta. 498:101–107.
2019.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Kanis JA and Glüer CC: An update on the
diagnosis and assessment of osteoporosis with densitometry.
Committee of Scientific Advisors, International Osteoporosis
Foundation. Osteoporos Int. 11:192–202. 2000.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Lamichhane AP: Osteoporosis-an update.
JNMA J Nepal Med Assoc. 44:60–66. 2005.PubMed/NCBI
|
|
54
|
Rossini M, Adami S, Bertoldo F, Diacinti
D, Gatti D, Giannini S, Giusti A, Malavolta N, Minisola S, Osella
G, et al: Guidelines for the diagnosis, prevention and management
of osteoporosis. Reumatismo. 68:1–39. 2016.PubMed/NCBI View Article : Google Scholar
|
|
55
|
Binkley N and Buehring B: Beyond FRAX:
It's time to consider ‘sarco-osteopenia’. J Clin Densitom.
12:413–416. 2009.PubMed/NCBI View Article : Google Scholar
|
|
56
|
He H, Liu Y, Tian Q, Papasian CJ, Hu T and
Deng HW: Relationship of sarcopenia and body composition with
osteoporosis. Osteoporos Int. 27:473–482. 2016.PubMed/NCBI View Article : Google Scholar
|
|
57
|
Kirk B, Zanker J and Duque G:
Osteosarcopenia: Epidemiology, diagnosis, and treatment-facts and
numbers. J Cachexia Sarcopenia Muscle. 11:609–618. 2020.PubMed/NCBI View Article : Google Scholar
|
|
58
|
Tarantino U, Baldi J, Celi M, Rao C, Liuni
FM, Iundusi R and Gasbarra E: Osteoporosis and sarcopenia: The
connections. Aging Clin Exp Res. 25 (Suppl 1):S93–S95.
2013.PubMed/NCBI View Article : Google Scholar
|
|
59
|
Frontera WR, Zayas AR and Rodriguez N:
Aging of human muscle: Understanding sarcopenia at the single
muscle cell level. Phys Med Rehabil Clin N Am. 23:201–7, xiii.
2012.PubMed/NCBI View Article : Google Scholar
|
|
60
|
Sumnik Z, Land C, Coburger S, Neu C, Manz
F, Hrach K and Schoenau E: The muscle-bone unit in adulthood:
Influence of sex, height, age and gynecological history on the bone
mineral content and muscle cross-sectional area. J Musculoskelet
Neuronal Interact. 6:195–200. 2006.PubMed/NCBI
|
|
61
|
Frost HM: Why do bone strength and ‘mass’
in aging adults become unresponsive to vigorous exercise? Insights
of the Utah paradigm. J Bone Miner Metab. 17:90–97. 1999.PubMed/NCBI View Article : Google Scholar
|
|
62
|
Seeman E: Pathogenesis of bone fragility
in women and men. Lancet. 359:1841–1850. 2002.PubMed/NCBI View Article : Google Scholar
|
|
63
|
Miyakoshi N, Hongo M, Mizutani Y and
Shimada Y: Prevalence of sarcopenia in Japanese women with
osteopenia and osteoporosis. J Bone Miner Metab. 31:556–561.
2013.PubMed/NCBI View Article : Google Scholar
|
|
64
|
Frost HM and Schönau E: The ‘muscle-bone
unit’ in children and adolescents: A 2000 overview. J Pediatr
Endocrinol Metab. 13:571–590. 2000.PubMed/NCBI View Article : Google Scholar
|
|
65
|
Žofková I: Hormonal aspects of the
muscle-bone unit. Physiol Res. 57 (Suppl 1):S159–S169.
2008.PubMed/NCBI View Article : Google Scholar
|
|
66
|
Regan JN, Trivedi T, Guise TA and Waning
DL: The Role of TGFβ in bone-muscle crosstalk. Curr Osteoporos Rep.
15:18–23. 2017.PubMed/NCBI View Article : Google Scholar
|
|
67
|
Lam H and Qin YX: The effects of
frequency-dependent dynamic muscle stimulation on inhibition of
trabecular bone loss in a disuse model. Bone. 43:1093–1100.
2008.PubMed/NCBI View Article : Google Scholar
|
|
68
|
Tagliaferri C, Wittrant Y, Davicco MJ,
Walrand S and Coxam V: Muscle and bone, two interconnected tissues.
Ageing Res Rev. 21:55–70. 2015.PubMed/NCBI View Article : Google Scholar
|
|
69
|
Kawao N and Kaji H: Interactions between
muscle tissues and bone metabolism. J Cell Biochem. 116:687–695.
2015.PubMed/NCBI View Article : Google Scholar
|
|
70
|
Buehring B and Binkley N: Myostatin-the
holy grail for muscle, bone, and fat? Curr Osteoporos Rep.
11:407–414. 2013.PubMed/NCBI View Article : Google Scholar
|
|
71
|
Kawatsura R, Hara Y, Akiyama M, Tachikawa
N and Nakahama KI: Gap junctional intercellular communication
attenuates osteoclastogenesis induced by activated osteoblasts.
Biochem Biophys Res Commun. 597:71–76. 2022.PubMed/NCBI View Article : Google Scholar
|
|
72
|
Loiselle AE, Paul EM, Lewis GS and Donahue
HJ: Osteoblast and osteocyte-specific loss of Connexin43 results in
delayed bone formation and healing during murine fracture healing.
J Orthop Res. 31:147–154. 2013.PubMed/NCBI View Article : Google Scholar
|
|
73
|
Komori T: Functions of osteocalcin in
bone, pancreas, testis, and muscle. Int J Mol Sci.
21(7513)2020.PubMed/NCBI View Article : Google Scholar
|
|
74
|
Lai X, Price C, Lu XL and Wang L: Imaging
and quantifying solute transport across periosteum: Implications
for muscle-bone crosstalk. Bone. 66:82–89. 2014.PubMed/NCBI View Article : Google Scholar
|
|
75
|
Laurent MR, Dedeyne L, Dupont J, Mellaerts
B, Dejaeger M and Gielen E: Age-related bone loss and sarcopenia in
men. Maturitas. 122:51–56. 2019.PubMed/NCBI View Article : Google Scholar
|
|
76
|
MacDonald BT and He X: Frizzled and LRP5/6
receptors for Wnt/β-catenin signaling. Cold Spring Harb Perspect
Biol. 4(a007880)2012.PubMed/NCBI View Article : Google Scholar
|
|
77
|
Maeda K, Kobayashi Y, Udagawa N, Uehara S,
Ishihara A, Mizoguchi T, Kikuchi Y, Takada I, Kato S, Kani S, et
al: Wnt5a-Ror2 signaling between osteoblast-lineage cells and
osteoclast precursors enhances osteoclastogenesis. Nat Med.
18:405–412. 2012.PubMed/NCBI View Article : Google Scholar
|
|
78
|
Girardi F and Le Grand F: Wnt signaling in
skeletal muscle development and regeneration. Prog Mol Biol Transl
Sci. 153:157–179. 2018.PubMed/NCBI View Article : Google Scholar
|
|
79
|
Tajbakhsh S, Borello U, Vivarelli E, Kelly
R, Papkoff J, Duprez D, Buckingham M and Cossu G: Differential
activation of Myf5 and MyoD by different Wnts in explants of mouse
paraxial mesoderm and the later activation of myogenesis in the
absence of Myf5. Development. 125:4155–4162. 1998.PubMed/NCBI View Article : Google Scholar
|
|
80
|
Otto A, Schmidt C and Patel K: Pax3 and
Pax7 expression and regulation in the avian embryo. Anat Embryol
(Berl). 211:293–310. 2006.PubMed/NCBI View Article : Google Scholar
|
|
81
|
Otto A, Schmidt C, Luke G, Allen S,
Valasek P, Muntoni F, Lawrence-Watt D and Patel K: Canonical Wnt
signalling induces satellite-cell proliferation during adult
skeletal muscle regeneration. J Cell Sci. 121(Pt 17):2939–2950.
2008.PubMed/NCBI View Article : Google Scholar
|
|
82
|
Ko W, Sohn JH, Jang JH, Ahn JS, Kang DG,
Lee HS, Kim JS, Kim YC and Oh H: Inhibitory effects of
alternaramide on inflammatory mediator expression through
TLR4-MyD88-mediated inhibition of NF-кB and MAPK pathway signaling
in lipopolysaccharide-stimulated RAW264.7 and BV2 cells. Chem Biol
Interact. 244:16–26. 2016.PubMed/NCBI View Article : Google Scholar
|
|
83
|
Brigelius-Flohé R and Flohé L: Basic
principles and emerging concepts in the redox control of
transcription factors. Antioxid Redox Signal. 15:2335–2381.
2011.PubMed/NCBI View Article : Google Scholar
|
|
84
|
Bellezza I, Mierla AL and Minelli A: Nrf2
and NF-κB and their concerted modulation in cancer pathogenesis and
progression. Cancers (Basel). 2:483–497. 2010.PubMed/NCBI View Article : Google Scholar
|
|
85
|
Pan H, Wang H, Wang X, Zhu L and Mao L:
The absence of Nrf2 enhances NF-κB-dependent inflammation following
scratch injury in mouse primary cultured astrocytes. Mediators
Inflamm. 2012(217580)2012.PubMed/NCBI View Article : Google Scholar
|
|
86
|
Canning P, Sorrell FJ and Bullock AN:
Structural basis of Keap1 interactions with Nrf2. Free Radic Biol
Med. 88(Pt B):101–107. 2015.PubMed/NCBI View Article : Google Scholar
|
|
87
|
Cuthbertson D, Smith K, Babraj J, Leese G,
Waddell T, Atherton P, Wackerhage H, Taylor PM and Rennie MJ:
Anabolic signaling deficits underlie amino acid resistance of
wasting, aging muscle. FASEB J. 19:422–424. 2005.PubMed/NCBI View Article : Google Scholar
|
|
88
|
Vasilaki A, McArdle F, Iwanejko LM and
McArdle A: Adaptive responses of mouse skeletal muscle to
contractile activity: The effect of age. Mech Ageing Dev.
127:830–839. 2006.PubMed/NCBI View Article : Google Scholar
|
|
89
|
Yang SY, Hoy M, Fuller B, Sales KM,
Seifalian AM and Winslet MC: Pretreatment with insulin-like growth
factor I protects skeletal muscle cells against oxidative damage
via PI3K/Akt and ERK1/2 MAPK pathways. Lab Invest. 90:391–401.
2010.PubMed/NCBI View Article : Google Scholar
|
|
90
|
Bodine SC, Stitt TN, Gonzalez M, Kline WO,
Stover GL, Bauerlein R, Zlotchenko E, Scrimgeour A, Lawrence JC,
Glass DJ and Yancopoulos GD: Akt/mTOR pathway is a crucial
regulator of skeletal muscle hypertrophy and can prevent muscle
atrophy in vivo. Nat Cell Biol. 3:1014–1019. 2001.PubMed/NCBI View Article : Google Scholar
|
|
91
|
Bonetto A, Aydogdu T, Jin X, Zhang Z, Zhan
R, Puzis L, Koniaris LG and Zimmers TA: JAK/STAT3 pathway
inhibition blocks skeletal muscle wasting downstream of IL-6 and in
experimental cancer cachexia. Am J Physiol Endocrinol Metab.
303:E410–E421. 2012.PubMed/NCBI View Article : Google Scholar
|
|
92
|
Allen DL and Unterman TG: Regulation of
myostatin expression and myoblast differentiation by FoxO and SMAD
transcription factors. Am J Physiol Cell Physiol. 292:C188–C199.
2007.PubMed/NCBI View Article : Google Scholar
|
|
93
|
Tarantino U, Piccirilli E, Fantini M,
Baldi J, Gasbarra E and Bei R: Sarcopenia and fragility fractures:
Molecular and clinical evidence of the bone-muscle interaction. J
Bone Joint Surg Am. 97:429–437. 2015.PubMed/NCBI View Article : Google Scholar
|
|
94
|
Brotto M, Invernizzi M, Ireland A and
Klein GL: Editorial: Osteoporosis and the role of muscle. Front
Endocrinol (Lausanne). 13(951298)2022.PubMed/NCBI View Article : Google Scholar
|
|
95
|
Karsenty G and Mera P: Molecular bases of
the crosstalk between bone and muscle. Bone. 115:43–49.
2018.PubMed/NCBI View Article : Google Scholar
|
|
96
|
Brotto M and Johnson ML: Endocrine
crosstalk between muscle and bone. Curr Osteoporos Rep. 12:135–141.
2014.PubMed/NCBI View Article : Google Scholar
|
|
97
|
Binkley N, Krueger D and Buehring B:
What's in a name revisited: Should osteoporosis and sarcopenia be
considered components of ‘dysmobility syndrome?’. Osteoporos Int.
24:2955–2959. 2013.PubMed/NCBI View Article : Google Scholar
|
|
98
|
Greenhill C: Unravelling the genetics of
osteoporosis. Nat Rev Endocrinol. 15(129)2019.PubMed/NCBI View Article : Google Scholar
|
|
99
|
Tikkanen E, Gustafsson S, Amar D,
Shcherbina A, Waggott D, Ashley EA and Ingelsson E: Biological
insights into muscular strength: Genetic findings in the UK
Biobank. Sci Rep. 8(6451)2018.PubMed/NCBI View Article : Google Scholar
|
|
100
|
Urano T and Inoue S: Recent genetic
discoveries in osteoporosis, sarcopenia and obesity. Endocr J.
62:475–484. 2015.PubMed/NCBI View Article : Google Scholar
|
|
101
|
Karasik D, Cupples LA, Hannan MT and Kiel
DP: Genome screen for a combined bone phenotype using principal
component analysis: The Framingham study. Bone. 34:547–556.
2004.PubMed/NCBI View Article : Google Scholar
|
|
102
|
Huang J, Hsu YH, Mo C, Abreu E, Kiel DP,
Bonewald LF, Brotto M and Karasik D: METTL21C is a potential
pleiotropic gene for osteoporosis and sarcopenia acting through the
modulation of the NF-κB signaling pathway. J Bone Miner Res.
29:1531–1540. 2014.PubMed/NCBI View Article : Google Scholar
|
|
103
|
Hirschfeld HP, Kinsella R and Duque G:
Osteosarcopenia: Where bone, muscle, and fat collide. Osteoporos
Int. 28:2781–2790. 2017.PubMed/NCBI View Article : Google Scholar
|
|
104
|
Gomarasca M, Banfi G and Lombardi G:
Myokines: The endocrine coupling of skeletal muscle and bone. Adv
Clin Chem. 94:155–218. 2020.PubMed/NCBI View Article : Google Scholar
|
|
105
|
Huang J, Romero-Suarez S, Lara N, Mo C,
Kaja S, Brotto L, Dallas SL, Johnson ML, Jähn K, Bonewald LF and
Brotto M: Crosstalk between MLO-Y4 osteocytes and C2C12 muscle
cells is mediated by the Wnt/β-catenin pathway. JBMR Plus.
1:86–100. 2017.PubMed/NCBI View Article : Google Scholar
|
|
106
|
Scimeca M, Centofanti F, Celi M, Gasbarra
E, Novelli G, Botta A and Tarantino U: Vitamin D receptor in muscle
atrophy of elderly patients: A key element of
osteoporosis-sarcopenia connection. Aging Dis. 9:952–964.
2018.PubMed/NCBI View Article : Google Scholar
|
|
107
|
DiGirolamo DJ, Clemens TL and Kousteni S:
The skeleton as an endocrine organ. Nat Rev Rheumatol. 8:674–683.
2012.PubMed/NCBI View Article : Google Scholar
|
|
108
|
Lebrasseur NK, Achenbach SJ, Melton LJ
III, Amin S and Khosla S: Skeletal muscle mass is associated with
bone geometry and microstructure and serum insulin-like growth
factor binding protein-2 levels in adult women and men. J Bone
Miner Res. 27:2159–2169. 2012.PubMed/NCBI View Article : Google Scholar
|
|
109
|
Chen LY, Wu YH, Liu LK, Lee WJ, Hwang AC,
Peng LN, Lin MH and Chen LK: Association among serum insulin-like
growth factor-1, frailty, muscle mass, bone mineral density, and
physical performance among community-dwelling middle-aged and older
adults in Taiwan. Rejuvenation Res. 21:270–277. 2018.PubMed/NCBI View Article : Google Scholar
|
|
110
|
Messier V, Rabasa-Lhoret R, Barbat-Artigas
S, Elisha B, Karelis AD and Aubertin-Leheudre M: Menopause and
sarcopenia: A potential role for sex hormones. Maturitas.
68:331–336. 2011.PubMed/NCBI View Article : Google Scholar
|
|
111
|
Notelovitz M: Androgen effects on bone and
muscle. Fertil Steril. 77 (Suppl 4):S34–S41. 2002.PubMed/NCBI View Article : Google Scholar
|
|
112
|
Hansen M: Female hormones: Do they
influence muscle and tendon protein metabolism? Proc Nutr Soc.
77:32–41. 2018.PubMed/NCBI View Article : Google Scholar
|
|
113
|
Colaianni G, Storlino G, Sanesi L, Colucci
S and Grano M: Myokines and osteokines in the pathogenesis of
muscle and bone diseases. Curr Osteoporos Rep. 18:401–407.
2020.PubMed/NCBI View Article : Google Scholar
|
|
114
|
Gonzalez-Gil AM and Elizondo-Montemayor L:
The role of exercise in the interplay between myokines,
hepatokines, osteokines, adipokines, and modulation of inflammation
for energy substrate redistribution and fat mass loss: A review.
Nutrients. 12(1899)2020.PubMed/NCBI View Article : Google Scholar
|
|
115
|
Liu Y, Lehar A, Rydzik R, Chandok H, Lee
YS, Youngstrom DW, George J, Matzuk MM, Germain-Lee EL and Lee SJ:
Local versus systemic control of bone and skeletal muscle mass by
components of the transforming growth factor-β signaling pathway.
Proc Natl Acad Sci USA. 118(e2111401118)2021.PubMed/NCBI View Article : Google Scholar
|
|
116
|
Omosule CL, Joseph D, Weiler B, Gremminger
VL, Silvey S, Jeong Y, Rafique A, Krueger P, Kleiner S and Phillips
CL: Combinatorial inhibition of myostatin and activin A improves
femoral bone properties in the G610C mouse model of osteogenesis
imperfecta. J Bone Miner Res. 37:938–953. 2022.PubMed/NCBI View Article : Google Scholar
|
|
117
|
Du Y, Zhang L, Wang Z, Zhao X and Zou J:
Endocrine regulation of extra-skeletal organs by bone-derived
secreted protein and the effect of mechanical stimulation. Front
Cell Dev Biol. 9(778015)2021.PubMed/NCBI View Article : Google Scholar
|
|
118
|
Han Y, You X, Xing W, Zhang Z and Zou W:
Paracrine and endocrine actions of bone-the functions of secretory
proteins from osteoblasts, osteocytes, and osteoclasts. Bone Res.
6(16)2018.PubMed/NCBI View Article : Google Scholar
|
|
119
|
Sutherland MK, Geoghegan JC, Yu C, Turcott
E, Skonier JE, Winkler DG and Latham JA: Sclerostin promotes the
apoptosis of human osteoblastic cells: A novel regulation of bone
formation. Bone. 35:828–835. 2004.PubMed/NCBI View Article : Google Scholar
|
|
120
|
Spatz JM, Fields EE, Yu EW, Divieti
Pajevic P, Bouxsein ML, Sibonga JD, Zwart SR and Smith SM: Serum
sclerostin increases in healthy adult men during bed rest. J Clin
Endocrinol Metab. 97:E1736–E1740. 2012.PubMed/NCBI View Article : Google Scholar
|
|
121
|
Meex RCR, Blaak EE and van Loon LJC:
Lipotoxicity plays a key role in the development of both insulin
resistance and muscle atrophy in patients with type 2 diabetes.
Obes Rev. 20:1205–1217. 2019.PubMed/NCBI View Article : Google Scholar
|
|
122
|
Yu B, Huo L, Liu Y, Deng P, Szymanski J,
Li J, Luo X, Hong C, Lin J and Wang CY: PGC-1α controls skeletal
stem cell fate and bone-fat balance in osteoporosis and skeletal
aging by inducing TAZ. Cell Stem Cell. 23:615–623. 2018.PubMed/NCBI View Article : Google Scholar
|
|
123
|
Wong SK, Chin KY, Suhaimi FH, Ahmad F and
Ima-Nirwana S: The relationship between metabolic syndrome and
osteoporosis: A review. Nutrients. 8(347)2016.PubMed/NCBI View Article : Google Scholar
|
|
124
|
Li W, Xu P, Wang C, Ha X, Gu Y, Wang Y,
Zhang J and Xie J: The effects of fat-induced obesity on bone
metabolism in rats. Obes Res Clin Pract. 11:454–463.
2017.PubMed/NCBI View Article : Google Scholar
|
|
125
|
Ansari MGA, Hussain SD, Wani KA, Yakout
SM, Al-Disi D, Alokail MS, Reginster JY and Al-Daghri NM: Influence
of bone mineral density in circulating adipokines among
postmenopausal Arab women. Saudi J Biol Sci. 27:374–379.
2020.PubMed/NCBI View Article : Google Scholar
|
|
126
|
Liu Y and Sweeney G: Adiponectin action in
skeletal muscle. Best Pract Res Clin Endocrinol Metab. 28:33–41.
2014.PubMed/NCBI View Article : Google Scholar
|
|
127
|
Cervellati C, Bonaccorsi G, Bergamini CM,
Fila E, Greco P, Valacchi G, Massari L, Gonelli A and Tisato V:
Association between circulatory levels of adipokines and bone
mineral density in postmenopausal women. Menopause. 23:984–992.
2016.PubMed/NCBI View Article : Google Scholar
|
|
128
|
Gomes MM, da Silva MMR, de Araújo IM and
de Paula FJA: Bone, fat, and muscle interactions in health and
disease. Arch Endocrinol Metab. 66:611–620. 2022.PubMed/NCBI View Article : Google Scholar
|
|
129
|
Kir S, White JP, Kleiner S, Kazak L, Cohen
P, Baracos VE and Spiegelman BM: Tumour-derived PTH-related protein
triggers adipose tissue browning and cancer cachexia. Nature.
513:100–104. 2014.PubMed/NCBI View Article : Google Scholar
|
|
130
|
Tuttle CSL, Thang LAN and Maier AB:
Markers of inflammation and their association with muscle strength
and mass: A systematic review and meta-analysis. Ageing Res Rev.
64(101185)2020.PubMed/NCBI View Article : Google Scholar
|
|
131
|
Ali S and Garcia JM: Sarcopenia, cachexia
and aging: Diagnosis, mechanisms and therapeutic options-a
mini-review. Gerontology. 60:294–305. 2014.PubMed/NCBI View Article : Google Scholar
|
|
132
|
Jung YS, Hwang HJ, Yun BH, Chon SJ, Cho S,
Choi YS, Kim YT, Lee BS and Seo SK: Renal function is associated
with bone mineral density and arterial stiffness in healthy
postmenopausal women. Gynecol Obstet Invest. 78:124–129.
2014.PubMed/NCBI View Article : Google Scholar
|
|
133
|
Mohsin S, Baniyas MM, AlDarmaki RS, Tekes
K, Kalász H and Adeghate EA: An update on therapies for the
treatment of diabetes-induced osteoporosis. Expert Opin Biol Ther.
19:937–948. 2019.PubMed/NCBI View Article : Google Scholar
|
|
134
|
Fricke O, Beccard R, Semler O and Schoenau
E: Analyses of muscular mass and function: The impact on bone
mineral density and peak muscle mass. Pediatr Nephrol.
25:2393–2400. 2010.PubMed/NCBI View Article : Google Scholar
|
|
135
|
Edwards MH, Dennison EM, Aihie Sayer A,
Fielding R and Cooper C: Osteoporosis and sarcopenia in older age.
Bone. 80:126–130. 2015.PubMed/NCBI View Article : Google Scholar
|
|
136
|
Barbé-Tuana F, Funchal G, Schmitz CRR,
Maurmann RM and Bauer ME: The interplay between immunosenescence
and age-related diseases. Semin Immunopathol. 42:545–557.
2020.PubMed/NCBI View Article : Google Scholar
|
|
137
|
Stefanaki C, Pervanidou P, Boschiero D and
Chrousos GP: Chronic stress and body composition disorders:
Implications for health and disease. Hormones (Athens). 17:33–43.
2018.PubMed/NCBI View Article : Google Scholar
|
|
138
|
JafariNasabian P, Inglis JE, Reilly W,
Kelly OJ and Ilich JZ: Aging human body: Changes in bone, muscle
and body fat with consequent changes in nutrient intake. J
Endocrinol. 234:R37–R51. 2017.PubMed/NCBI View Article : Google Scholar
|
|
139
|
Kanis JA, Johansson H, Johnell O, Oden A,
De Laet C, Eisman JA, Pols H and Tenenhouse A: Alcohol intake as a
risk factor for fracture. Osteoporos Int. 16:737–742.
2005.PubMed/NCBI View Article : Google Scholar
|
|
140
|
Renoud A, Ecochard R, Marchand F,
Chapurlat R and Szulc P: Predictive parameters of accelerated
muscle loss in men-MINOS study. Am J Med. 127:554–561.
2014.PubMed/NCBI View Article : Google Scholar
|
|
141
|
Steffl M, Bohannon RW, Petr M, Kohlikova E
and Holmerova I: Relation between cigarette smoking and sarcopenia:
Meta-analysis. Physiol Res. 64:419–426. 2015.PubMed/NCBI View Article : Google Scholar
|
|
142
|
Goljanek-Whysall K, Iwanejko LA, Vasilaki
A, Pekovic-Vaughan V and McDonagh B: Ageing in relation to skeletal
muscle dysfunction: Redox homoeostasis to regulation of gene
expression. Mamm Genome. 27:341–357. 2016.PubMed/NCBI View Article : Google Scholar
|
|
143
|
Schoenfeld BJ, Ogborn D and Krieger JW:
Effects of resistance training frequency on measures of muscle
hypertrophy: A systematic review and meta-analysis. Sports Med.
46:1689–1697. 2016.PubMed/NCBI View Article : Google Scholar
|
|
144
|
DiVasta AD and Gordon CM: Exercise and
bone: Where do we stand? Metabolism. 62:1714–1717. 2013.PubMed/NCBI View Article : Google Scholar
|
|
145
|
Harijanto C, Lim A, Vogrin S and Duque G:
Does whole-body vibration training have a concurrent effect on bone
and muscle health? A systematic review and meta-analysis.
Gerontology. 68:601–611. 2022.PubMed/NCBI View Article : Google Scholar
|
|
146
|
Zeng Z, Liang J, Wu L, Zhang H, Lv J and
Chen N: Exercise-Induced Autophagy suppresses sarcopenia through
Akt/mTOR and Akt/FoxO3a signal pathways and AMPK-mediated
mitochondrial quality control. Front Physiol.
11(583478)2020.PubMed/NCBI View Article : Google Scholar
|
|
147
|
Ross AC, Manson JE, Abrams SA, Aloia JF,
Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL,
Jones G, et al: The 2011 report on dietary reference intakes for
calcium and vitamin D from the Institute of Medicine: What
clinicians need to know. J Clin Endocrinol Metab. 96:53–58.
2011.PubMed/NCBI View Article : Google Scholar
|
|
148
|
Schnatz PF, Marakovits KA, Dubois M and
O'Sullivan DM: Osteoporosis screening and treatment guidelines: Are
they being followed? Menopause. 18:1072–1078. 2011.PubMed/NCBI View Article : Google Scholar
|
|
149
|
Bauer J, Biolo G, Cederholm T, Cesari M,
Cruz-Jentoft AJ, Morley JE, Phillips S, Sieber C, Stehle P, Teta D,
et al: Evidence-based recommendations for optimal dietary protein
intake in older people: A position paper from the PROT-AGE Study
Group. J Am Med Dir Assoc. 14:542–559. 2013.PubMed/NCBI View Article : Google Scholar
|
|
150
|
Shams-White MM, Chung M, Du M, Fu Z,
Insogna KL, Karlsen MC, LeBoff MS, Shapses SA, Sackey J, Wallace TC
and Weaver CM: Dietary protein and bone health: A systematic review
and meta-analysis from the National Osteoporosis Foundation. Am J
Clin Nutr. 105:1528–1543. 2017.PubMed/NCBI View Article : Google Scholar
|
|
151
|
Tang BM, Eslick GD, Nowson C, Smith C and
Bensoussan A: Use of calcium or calcium in combination with vitamin
D supplementation to prevent fractures and bone loss in people aged
50 years and older: A meta-analysis. Lancet. 370:657–666.
2007.PubMed/NCBI View Article : Google Scholar
|
|
152
|
Hassan EB and Duque G: Osteosarcopenia: A
new geriatric syndrome. Aust Fam Physician. 46:849–853.
2017.PubMed/NCBI
|
|
153
|
Polito A, Barnaba L, Ciarapica D and
Azzini E: Osteosarcopenia: A narrative review on clinical studies.
Int J Mol Sci. 23(5591)2022.PubMed/NCBI View Article : Google Scholar
|
|
154
|
Klein GL: Pharmacologic treatments to
preserve bone and muscle mass in osteosarcopenia. Curr Osteoporos
Rep. 18:228–231. 2020.PubMed/NCBI View Article : Google Scholar
|
|
155
|
Inoue T, Maeda K, Nagano A, Shimizu A,
Ueshima J, Murotani K, Sato K, Hotta K, Morishita S and Tsubaki A:
Related factors and clinical outcomes of osteosarcopenia: A
narrative review. Nutrients. 13(291)2021.PubMed/NCBI View Article : Google Scholar
|
|
156
|
Fagundes Belchior G, Kirk B, Pereira da
Silva EA and Duque G: Osteosarcopenia: Beyond age-related muscle
and bone loss. Eur Geriatr Med. 11:715–724. 2020.PubMed/NCBI View Article : Google Scholar
|
|
157
|
Li B, Wang P, Jiao J, Wei H, Xu W and Zhou
P: Roles of the RANKL-RANK axis in immunity-implications for
pathogenesis and treatment of bone metastasis. Front Immunol.
13(824117)2022.PubMed/NCBI View Article : Google Scholar
|
|
158
|
Ono T, Hayashi M, Sasaki F and Nakashima
T: RANKL biology: Bone metabolism, the immune system, and beyond.
Inflamm Regen. 40(2)2020.PubMed/NCBI View Article : Google Scholar
|
|
159
|
Boyce BF, Xiu Y, Li J, Xing L and Yao Z:
NF-κB-Mediated regulation of osteoclastogenesis. Endocrinol Metab
(Seoul). 30:35–44. 2015.PubMed/NCBI View Article : Google Scholar
|
|
160
|
Bonnet N, Bourgoin L, Biver E, Douni E and
Ferrari S: RANKL inhibition improves muscle strength and insulin
sensitivity and restores bone mass. J Clin Invest.
130(3329)2020.PubMed/NCBI View Article : Google Scholar
|
|
161
|
Hamoudi D, Marcadet L, Piette Boulanger A,
Yagita H, Bouredji Z, Argaw A and Frenette J: An anti-RANKL
treatment reduces muscle inflammation and dysfunction and
strengthens bone in dystrophic mice. Hum Mol Genet. 28:3101–3112.
2019.PubMed/NCBI View Article : Google Scholar
|
|
162
|
Junnila RK, List EO, Berryman DE, Murrey
JW and Kopchick JJ: The GH/IGF-1 axis in ageing and longevity. Nat
Rev Endocrinol. 9:366–376. 2013.PubMed/NCBI View Article : Google Scholar
|
|
163
|
Altowati MA, Shepherd S, McGrogan P,
Russell RK, Ahmed SF and Wong SC: Effects of recombinant human
growth hormone in children with crohn's disease on the muscle-bone
unit: A preliminary study. Horm Res Paediatr. 90:128–131.
2018.PubMed/NCBI View Article : Google Scholar
|
|
164
|
Pawlikowska-Haddal A: Growth hormone
therapy with norditropin (somatropin) in growth hormone deficiency.
Expert Opin Biol Ther. 13:927–932. 2013.PubMed/NCBI View Article : Google Scholar
|
|
165
|
Lane JM, Russell L and Khan SN:
Osteoporosis. Clin Orthop Relat Res. (372):139–150. 2000.PubMed/NCBI View Article : Google Scholar
|
|
166
|
Cruz-Jentoft AJ, Landi F, Schneider SM,
Zúñiga C, Arai H, Boirie Y, Chen LK, Fielding RA, Martin FC, Michel
JP, et al: Prevalence of and interventions for sarcopenia in ageing
adults: A systematic review. Report of the International Sarcopenia
Initiative (EWGSOP and IWGS). Age Ageing. 43:748–759.
2014.PubMed/NCBI View Article : Google Scholar
|
|
167
|
Kakehi S, Wakabayashi H, Inuma H, Inose T,
Shioya M, Aoyama Y, Hara T, Uchimura K, Tomita K, Okamoto M, et al:
Rehabilitation nutrition and exercise therapy for sarcopenia. World
J Mens Health. 40:1–10. 2022.PubMed/NCBI View Article : Google Scholar
|
|
168
|
Pana A, Sourtzi P, Kalokairinou A and
Velonaki VS: Sarcopenia and polypharmacy among older adults: A
scoping review of the literature. Arch Gerontol Geriatr.
98(104520)2022.PubMed/NCBI View Article : Google Scholar
|
|
169
|
Snyder PJ, Kopperdahl DL, Stephens-Shields
AJ, Ellenberg SS, Cauley JA, Ensrud KE, Lewis CE, Barrett-Connor E,
Schwartz AV, Lee DC, et al: Effect of testosterone treatment on
volumetric bone density and strength in older men with low
testosterone: A controlled clinical trial. JAMA Intern Med.
177:471–479. 2017.PubMed/NCBI View Article : Google Scholar
|
|
170
|
Velders M and Diel P: How sex hormones
promote skeletal muscle regeneration. Sports Med. 43:1089–1100.
2013.PubMed/NCBI View Article : Google Scholar
|
|
171
|
Dieli-Conwright CM, Spektor TM, Rice JC
and Todd Schroeder E: Oestradiol and SERM treatments influence
oestrogen receptor coregulator gene expression in human skeletal
muscle cells. Acta Physiol (Oxf). 197:187–196. 2009.PubMed/NCBI View Article : Google Scholar
|