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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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May-2023 Volume 25 Issue 5

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Case Report Open Access

Three cases of neurosyphilis diagnosed in the 21st century: A case report

  • Authors:
    • Ramona Andreea Codreanu Balaban
    • Any Axelerad
    • Daniela Musat
    • Anabella Cristiana Cioabla
    • Alina Zorina Stuparu
    • Silviu Docu Axelerad
    • Lavinia Florenta Muja

  • View Affiliations / Copyright

    Affiliations: Department of Neurology, ‘Sf. Ap Andrei’ Emergency County Clinical Hospital, 900591 Constanta, Romania, Faculty of General Medicine, ‘Vasile Goldis’ University, 317046 Arad, Romania
    Copyright: © Codreanu Balaban et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 201
    |
    Published online on: March 21, 2023
       https://doi.org/10.3892/etm.2023.11900
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Abstract

In the last decades, it has been considered that syphilis and its complications, including neurological damage, are able to be kept under control with proper epidemiological management. However, socio‑economic changes and the problem of antibiotic resistance have brought it back into the focus of clinicians. The present study reports on the cases of three male patients of different ages (28, 76 and 51 years) from different social backgrounds and occupations were provided (first patient, nurse; second patient, pensioner; third patient, navigator); they were confirmed to have neurosyphilis, clinically, paraclinically and by imaging. The complications that may occur in the evolution of the disease but also the beneficial effects of targeted, antisyphilitic and symptomatic therapy were outlined. The purpose of the present study was to highlight issues of major importance regarding neurosyphilis, particularly for neurologists, for whom diagnosis may be challenging. It is key for the neurologist to understand the clinical manifestations and limitations of current diagnostic tests. It is important to consider that a positive rapid plasma reagin test result without confirmation of the presence of Treponema pallidum antibodies in the cerebrospinal fluid may represent a false‑positive screening test.
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Copy and paste a formatted citation
Spandidos Publications style
Codreanu Balaban RA, Axelerad A, Musat D, Cioabla AC, Stuparu AZ, Axelerad SD and Muja LF: Three cases of neurosyphilis diagnosed in the 21st century: A case report. Exp Ther Med 25: 201, 2023.
APA
Codreanu Balaban, R.A., Axelerad, A., Musat, D., Cioabla, A.C., Stuparu, A.Z., Axelerad, S.D., & Muja, L.F. (2023). Three cases of neurosyphilis diagnosed in the 21st century: A case report. Experimental and Therapeutic Medicine, 25, 201. https://doi.org/10.3892/etm.2023.11900
MLA
Codreanu Balaban, R. A., Axelerad, A., Musat, D., Cioabla, A. C., Stuparu, A. Z., Axelerad, S. D., Muja, L. F."Three cases of neurosyphilis diagnosed in the 21st century: A case report". Experimental and Therapeutic Medicine 25.5 (2023): 201.
Chicago
Codreanu Balaban, R. A., Axelerad, A., Musat, D., Cioabla, A. C., Stuparu, A. Z., Axelerad, S. D., Muja, L. F."Three cases of neurosyphilis diagnosed in the 21st century: A case report". Experimental and Therapeutic Medicine 25, no. 5 (2023): 201. https://doi.org/10.3892/etm.2023.11900
Copy and paste a formatted citation
x
Spandidos Publications style
Codreanu Balaban RA, Axelerad A, Musat D, Cioabla AC, Stuparu AZ, Axelerad SD and Muja LF: Three cases of neurosyphilis diagnosed in the 21st century: A case report. Exp Ther Med 25: 201, 2023.
APA
Codreanu Balaban, R.A., Axelerad, A., Musat, D., Cioabla, A.C., Stuparu, A.Z., Axelerad, S.D., & Muja, L.F. (2023). Three cases of neurosyphilis diagnosed in the 21st century: A case report. Experimental and Therapeutic Medicine, 25, 201. https://doi.org/10.3892/etm.2023.11900
MLA
Codreanu Balaban, R. A., Axelerad, A., Musat, D., Cioabla, A. C., Stuparu, A. Z., Axelerad, S. D., Muja, L. F."Three cases of neurosyphilis diagnosed in the 21st century: A case report". Experimental and Therapeutic Medicine 25.5 (2023): 201.
Chicago
Codreanu Balaban, R. A., Axelerad, A., Musat, D., Cioabla, A. C., Stuparu, A. Z., Axelerad, S. D., Muja, L. F."Three cases of neurosyphilis diagnosed in the 21st century: A case report". Experimental and Therapeutic Medicine 25, no. 5 (2023): 201. https://doi.org/10.3892/etm.2023.11900
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