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Risk factors and survival analysis of haemodialysis complicated with infective endocarditis

  • Authors:
    • Ya-Jing He
    • Cun-Si Ye
    • Ke-Yang Xu
    • Li-Li Yang
    • Kai-Le Wang
    • Xiao-Mei Wang
    • Mei-Yu Li
    • Yu Wu
    • Qi-Su Ying
    • Ming Wang
    • Shi-Jian Quan
    • Xiu Yang
  • View Affiliations / Copyright

    Affiliations: Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, P.R. China, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 529000, P.R. China, Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, SAR, P.R. China
    Copyright: © He et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 203
    |
    Published online on: March 21, 2023
       https://doi.org/10.3892/etm.2023.11902
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Abstract

The clinical features and risk factors for survival time were analysed in haemodialysis patients complicated with infective endocarditis. A total of 101 infective endocarditis (IE) patients treated at Hangzhou First People's Hospital, from January 1, 2012, to April 1, 2022, were included in the present study. Baseline demographic data and laboratory data were collected for statistical analysis of risk factors and survival time in the IE with haemodialysis group (HD‑IE group, n=15) and the IE without haemodialysis group (NHD‑IE group, n=86). Haemoglobin, red blood cells, C‑reactive protein, procalcitonin, serum albumin, diabetes, invasive procedures, positive blood bacteria culture, heart valve calcification ratio, and left ventricular ejection fraction level were risk factors for infective endocarditis complicated with haemodialysis (P<0.05). Compared with the NHD‑IE group, the HD‑IE group had an obviously increased risk of mortality (χ2=6.323, P=0.012). The univariate Cox regression analysis showed that age, haemoglobin, red blood cells, serum albumin, left ventricular ejection score, longest vegetation diameter, combined hypotension and diabetes were risk factors for death; furthermore, multivariate Cox regression showed that age (HR=1.187, P=0.015), combined hypotension (HR=0.921, P=0.025) and the longest vegetation diameter (HR=9.191, P=0.004) were independent risk factors affecting the survival of patients. Collectively, the present study revealed that the mortality rate of HD‑IE patients was higher than that of NHD‑IE patients. Older age, hypotension, and the longest vegetation diameter were independent risk factors affecting the survival of patients. For HD‑IE patients, active and effective antibiotic treatment or surgical treatment should be strongly recommended.
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Copy and paste a formatted citation
Spandidos Publications style
He Y, Ye C, Xu K, Yang L, Wang K, Wang X, Li M, Wu Y, Ying Q, Wang M, Wang M, et al: Risk factors and survival analysis of haemodialysis complicated with infective endocarditis. Exp Ther Med 25: 203, 2023.
APA
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X. ... Yang, X. (2023). Risk factors and survival analysis of haemodialysis complicated with infective endocarditis. Experimental and Therapeutic Medicine, 25, 203. https://doi.org/10.3892/etm.2023.11902
MLA
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X., Li, M., Wu, Y., Ying, Q., Wang, M., Quan, S., Yang, X."Risk factors and survival analysis of haemodialysis complicated with infective endocarditis". Experimental and Therapeutic Medicine 25.5 (2023): 203.
Chicago
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X., Li, M., Wu, Y., Ying, Q., Wang, M., Quan, S., Yang, X."Risk factors and survival analysis of haemodialysis complicated with infective endocarditis". Experimental and Therapeutic Medicine 25, no. 5 (2023): 203. https://doi.org/10.3892/etm.2023.11902
Copy and paste a formatted citation
x
Spandidos Publications style
He Y, Ye C, Xu K, Yang L, Wang K, Wang X, Li M, Wu Y, Ying Q, Wang M, Wang M, et al: Risk factors and survival analysis of haemodialysis complicated with infective endocarditis. Exp Ther Med 25: 203, 2023.
APA
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X. ... Yang, X. (2023). Risk factors and survival analysis of haemodialysis complicated with infective endocarditis. Experimental and Therapeutic Medicine, 25, 203. https://doi.org/10.3892/etm.2023.11902
MLA
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X., Li, M., Wu, Y., Ying, Q., Wang, M., Quan, S., Yang, X."Risk factors and survival analysis of haemodialysis complicated with infective endocarditis". Experimental and Therapeutic Medicine 25.5 (2023): 203.
Chicago
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X., Li, M., Wu, Y., Ying, Q., Wang, M., Quan, S., Yang, X."Risk factors and survival analysis of haemodialysis complicated with infective endocarditis". Experimental and Therapeutic Medicine 25, no. 5 (2023): 203. https://doi.org/10.3892/etm.2023.11902
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