Current perspectives in hypospadias research: A scoping review of articles published in 2021 (Review)
- Authors:
- Horea Gozar
- Zsolt Bara
- Emilia Dicu
- Zoltán Derzsi
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Affiliations: Clinic of Pediatric Surgery and Orthopedics, Târgu Mureș, County Emergency Clinical Hospital, Târgu Mureș 540136, Romania - Published online on: March 23, 2023 https://doi.org/10.3892/etm.2023.11910
- Article Number: 211
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Copyright: © Gozar et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
van der Horst HJR and de Wall LL: Hypospadias, all there is to know. Eur J Pediatr. 176:435–441. 2017.PubMed/NCBI View Article : Google Scholar | |
Kaefer M: Hypospadias. Semin Pediatr Surg. 30(151080)2021.PubMed/NCBI View Article : Google Scholar | |
Snodgrass P, Snodgrass W and Bush N: Parental concerns of boys with hypospadias. Res Rep Urol. 13:73–77. 2021.PubMed/NCBI View Article : Google Scholar | |
van Engelen H, Custers JAE, Kortmann BM, Oerlemans AJM, van Rooij IALM and Verhaak CM: Parental decisional regret after surgical treatment in young boys born with hypospadias. J Pediatr Urol. 17:691.e1–691.e7. 2021.PubMed/NCBI View Article : Google Scholar | |
Costa E, Fraga JC, Salle JP and Rosito N: Does parental opinion differ from the health care team regarding cosmesis after hypospadias repair? Rev Assoc Med Bras (1992). 67:33–38. 2021.PubMed/NCBI View Article : Google Scholar | |
Ceccarelli PL, Lucaccioni L, Poluzzi F, Bianchini A, Biondini D, Iughetti L and Predieri B: Hypospadias: Clinical approach, surgical technique and long-term outcome. BMC Pediatr. 21(523)2021.PubMed/NCBI View Article : Google Scholar | |
Hisamatsu E, Sugita Y, Haruna A, Shibata R and Yoshino K: The learning curve in proximal hypospadias repair. J Pediatr Urol. 17:330.e1–330.e6. 2021.PubMed/NCBI View Article : Google Scholar | |
Wang C, Ma N, Wang W, Endo Y, Chen W and Li S: Incised urethral diversion reduces the rate of fistula after one-stage hypospadias repair: A single-center retrospective controlled study. World J Urol. 39:4235–4240. 2021.PubMed/NCBI View Article : Google Scholar | |
Babu R and Chandrasekharam VVS: Meta-analysis comparing the outcomes of single stage (foreskin pedicled tube) versus two stage (foreskin free graft & foreskin pedicled flap) repair for proximal hypospadias in the last decade. J Pediatr Urol. 17:681–689. 2021.PubMed/NCBI View Article : Google Scholar | |
Ali MM, El-Hawy MM, Galal EM, Tawfiek ER and Anwar AZ: Results of two-stage transverse preputial island flap urethroplasty for proximal hypospadias with chordee that mandate division of the urethral plate. Cent European J Urol. 74:89–94. 2021.PubMed/NCBI View Article : Google Scholar | |
Chan YY, D'Oro A, Yerkes EB, Rosoklija I, Balmert LC, Lindgren BW, Gong EM, Liu DB, Johnson EK, Chu DI and Cheng EY: Challenging proximal hypospadias repairs: An evolution of technique for two stage repairs. J Pediatr Urol. 17:225.e1–225.e8. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhu X, Huang L, Wang J, Zhu H, Chen C, Wang L, Deng Y, Ma G, Guo Y and Ge Z: Comparative study of one-stage and the novel two-stage urethroplasty using the transected urethral plate and transverse preputial island flap (TPIF) for severe hypospadias: A single-center experience. Transl Pediatr. 10:843–850. 2021.PubMed/NCBI View Article : Google Scholar | |
Madec FX, Desplanches M, Chabaud M, Irtan S, Suply E and Audry G: Koyanagi urethroplasty for proximal hypospadias: A stage procedure? Prog Urol. 32:312–318. 2022.PubMed/NCBI View Article : Google Scholar | |
Vu TH, Viet Nguyen H, Quy Hong Q, Quang Pham H, Thanh Pham T, Hai Do Đ and Đo Truong T: Results of the one-stage proximal hypospadias repair with modified Koyanagi technique: A prospective cohort study in a single Vietnam centre. Ann Med Surg (Lond). 71(103012)2021.PubMed/NCBI View Article : Google Scholar | |
Acimi S, Abderrahmane N, Debbous L, Acimi MA and Mansouri J: Koyanagi-snow-hayashi urethroplasty in severe hypospadias repair: Between hope and reality. Urology. 152:129–135. 2021.PubMed/NCBI View Article : Google Scholar | |
Lin H, Wang YY, Li SB, Chen ZT and Su LJ: Staged transverse preputial island flap urethroplasty for some proximal hypospadias with moderate-to-severe chordee. BMC Urol. 21(182)2021.PubMed/NCBI View Article : Google Scholar | |
Silay MS, 't Hoen L, Bhatt N, Quaedackers J, Bogaert G, Dogan HS, Nijman RJM, Rawashdeh Y, Stein R, Tekgul S and Radmayr C: Are there any benefits of using an inlay graft in the treatment of primary hypospadias in children? A systematic review and metanalysis. J Pediatr Urol. 17:303–315. 2021.PubMed/NCBI View Article : Google Scholar | |
Swatesutipun V, Yoosuksomboon N and Zaontz MR: A novel transurethral approach to inlay oral mucosal graft urethroplasty technique for meatal and fossa navicularis stricture resulting from distal hypospadias repair. J Pediatr Urol. 17:585–586. 2021.PubMed/NCBI View Article : Google Scholar | |
Omran M, Sakr A, Elgalaly H, Fawzy A and Abdalla M: Narrow urethral plate augmentation in anterior and middle hypospadias repair: Onlay flap vs Inlay graft. A prospective randomized comparative study. J Pediatr Urol. 17:216.e1–216.e8. 2021.PubMed/NCBI View Article : Google Scholar | |
Chen S, Li Y, Ma N, Wang W, Xu L and Yang Z: Staged buccal mucosa graft urethroplasty for proximal hypospadias in children: A short- to mid-term follow-up retrospective study. Eur J Pediatr Surg. 31:420–426. 2021.PubMed/NCBI View Article : Google Scholar | |
Shandilya G, Kureel SN, Gupta A, Singh GP, Pandey A, Rawat JD and Wakhlu A: Bracka urethroplasty with buccal mucosa graft: Ergonomic management of penile skin dartos in the first stage to facilitate second-stage neourethral coverage. J Indian Assoc Pediatr Surg. 26:11–15. 2021.PubMed/NCBI View Article : Google Scholar | |
Tiwari C and Borkar N: Evaluation of tunica vaginalis free graft as a better alternative to tunica vaginalis pedicled flap for providing waterproof cover in stage II hypospadias repair. Afr J Paediatr Surg. 18:90–93. 2021.PubMed/NCBI View Article : Google Scholar | |
Favorito LA, da Silva Filho FS and de Resende Junior JA: A new option to prevent fistulas in anterior urethroplasty in patients with kippered urethra: The tunica vaginalis flap. Int Braz J Urol. 47:1032–1036. 2021.PubMed/NCBI View Article : Google Scholar | |
Radhakrishnan CN and Radhakrishna V: The tunica-vaginalis flap to prevent postoperative fistula following severe hypospadias repair: Has the search for Holy Grail ended? Actas Urol Esp (Engl Ed). 45:552–556. 2021.PubMed/NCBI View Article : Google Scholar | |
Obaidullah Shami HB, Obaid O, Alvi HF, Mahboob M and Akbar F: Outcomes of islanded scrotal raphe flap employment for skin shortage in complicated hypospadias repair. J Plast Reconstr Aesthet Surg. 74:3386–3393. 2021.PubMed/NCBI View Article : Google Scholar | |
Jordan A, Sumfest J and Desantis J: A new 3-stage approach for reoperative hypospadias. Ann Plast Surg. 88:544–548. 2022.PubMed/NCBI View Article : Google Scholar | |
Taneli C, Tanriverdi HI, Genc A, Sencan A, Gunsar C and Yilmaz O: Tubularized reconstructed plate urethroplasty: An alternative technique for distal hypospadias repair. Urology. 148:243–249. 2021.PubMed/NCBI View Article : Google Scholar | |
Abdel-Hamid El-Hawy M, Ali MM, Abdelhamid AM, Fawzy AM, Hussein A and Elsharkawy MSM: Long-term outcome of non-stented tubularized incised plate urethroplasty for distal hypospadias repair: A complication analysis. Cent European J Urol. 74:595–600. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhang J, Zhu S, Zhang L, Fu W, Hu J, Zhang Z and Jia W: The association between caudal block and urethroplasty complications of distal tubularized incised plate repair: Experience from a South China National Children's Medical Center. Transl Androl Urol. 10:2084–2090. 2021.PubMed/NCBI View Article : Google Scholar | |
Galal M, Taha DE, Elabden KZ, Nabeeh H and Abdelbaky T: The effect of pre-incision urethral plate width and glanular width on the outcome of tubularized incised urethral plate repair surgery in distal penile hypospadias, a prospective study. Urol J. 19:50–55. 2021.PubMed/NCBI View Article : Google Scholar | |
Ludovica D, Bianco M, Pelizzari A, Mandato F, Esposito C and Castagnetti M: Self-reported outcomes after the onset of puberty in patients undergoing primary distal hypospadias repair by the tubularized incised plate technique combined with preputial reconstruction vs circumcision: A norm related study. J Pediatr Surg. 56:1411–1416. 2021.PubMed/NCBI View Article : Google Scholar | |
Khirallah M and El-Dossuky N: Hybrid mathieu urethroplasty: A simple modification outcomes. Res Rep Urol. 13:473–478. 2021.PubMed/NCBI View Article : Google Scholar | |
Xie QG, Xia K, Li XP, Luo P, Li ZQ, Su C and Deng CH: Application of the Mathieu combined tunnel technique for repairing glans dehiscence after failed hypospadias repair. Asian J Androl. 24:311–316. 2022.PubMed/NCBI View Article : Google Scholar | |
Akdemir F, Kayıgil Ö and Okulu E: DORSAL plication technique for the treatment of congenital ventral penile curvature: Long-term outcomes of 72 cases. J Sex Med. 18:1715–1720. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhu XJ, Dong J, Ge Z and Guo YF: Staged urethroplasty by tubularization of reconstructed urethral plate using the preputial island flap for severe hypospadias. Zhonghua Nan Ke Xue. 27:134–139. 2021.PubMed/NCBI(In Chinese). | |
Ali MM and Anwar AZ: Experience with modified two stage inner preputial flap for repair of proximal hypospadias with chordee: A single institution study with intermediate follow up. J Pediatr Surg. 57:1404–1408. 2022.PubMed/NCBI View Article : Google Scholar | |
Aziz Tamer FA, El Zalabany Ahmed M and Lolah Magdy M: The modified Koyanagi technique versus two-staged urethroplasty using buccal mucosal graft in managing proximal hypospadias: A randomized clinical trial. Egypt J Surg. 40:633–639. 2021. | |
Lu J, Cen J, Wang W, Zhao H, Li P, Mo J, Chen Z, Tang Y, Wei J, Luo J, et al: Localization of external urethral orifice in coronary sulcus during urethroplasty in case of severe hypospadias accompanied by prostatic utricle cyst. BMC Urol. 21(149)2021.PubMed/NCBI View Article : Google Scholar | |
Akkary R, Ripepi M, Akokpe O, Louati H, Klipfel C and Geiss S: Two simple modifications can potentially change the future of proximal hypospadias surgery. Our series and a review of the literature. Int J Pediatr Adolesc Med. 8:172–176. 2021.PubMed/NCBI View Article : Google Scholar | |
Ding Y, Gu S, Xia X and Yu Z: Comparison of penile appearance and outcomes between prefabricated urethra and pre-implanted urethral plate for treatment of children with severe hypospadias: A retrospective study. Front Pediatr. 9(719551)2021.PubMed/NCBI View Article : Google Scholar | |
Chen S, Yang Z, Ma N, Wang WX, Xu LS, Liu QY and Li YQ: Scrotal septal flap and two-stage operation for complex hypospadias: A retrospective study. World J Clin Cases. 9:2983–2993. 2021.PubMed/NCBI View Article : Google Scholar | |
Lyu YQ, Yu L, Xie H, Huang YC, Li XX, Sun L, Liang Y and Chen F: Spongiosum-combined glanuloplasty reduces glans complications after proximal hypospadias repair. Asian J Androl. 23:532–536. 2021.PubMed/NCBI View Article : Google Scholar | |
Karakuş SC and Süzen A: Vertical plication: A penile curvature correction technique that reduces the need for urethral plate transection in penoscrotal hypospadias. J Pediatr Urol. 17:516.e1–516.e5. 2021.PubMed/NCBI View Article : Google Scholar | |
Ndiaye M, Sow Y, Sarr A, Thiam A, Faye ST, Ndour NS, Sine B, Zé-Ondo C, Sow O, Ndiath A, et al: Hypospadias treatment by tubulated pedicled preputial island flap according to the DUCKETT technique: Single-center experience in sub-Saharan Africa. Afr J Urol. 27(156)2021. | |
Rawashdeh YF, Hvistendal GM and Olsen LH: Foreskin transplantation between monozygotic twins discordant for hypospadias. Ugeskr Laeger. 183(V10200788)2021.PubMed/NCBI(In Danish). | |
Blanc T, Peycelon M, Siddiqui M, Muller C, Paye-Jaouen A and El-Ghoneimi A: Double-face preputial island flap revisited: Is it a reliable one-stage repair for severe hypospadias? World J Urol. 39:1613–1624. 2021.PubMed/NCBI View Article : Google Scholar | |
Fahiem-Ul-Hassan M, Jadhav V, Munianjanappa N, Saroja M and Santhanakrishnan R: Outcome of Buck's fascia repair with wingless glanuloplasty in distal penile hypospadias. Afr J Urol. 27(73)2021. | |
Keshk TAEH, El Sheikh YMO, El Rahman MA, Rezq HSA and Dawod HAA: New modification of Koyanagi technique using dartos muscle flap in management of proximal hypospadias. Egypt J Hosp Med. 84:1832–1838. 2021. | |
Tudu HC, Mishra A, Mohanty SK, Prashanthi N, Roy I, Bhardwaj P and Pujari PS: Outcome of proximal hypospadias repair in children using standard surgical technique with intermediate vascularised flap-a retrospective cohort study. J Clin Diagn Res. 15:9–12. 2021. | |
Long CJ, van Batavia J, Wisniewski AB, Aston CE, Baskin L, Cheng EY, Lakshmanan Y, Meyer T, Kropp B, Palmer B, et al: Post-operative complications following masculinizing genitoplasty in moderate to severe genital atypia: Results from a multicenter, observational prospective cohort study. J Pediatr Urol. 17:379–386. 2021.PubMed/NCBI View Article : Google Scholar | |
Askarpour S, Peyvasteh M, Mohamadi A and Khoshkhabar M: Comparative study of modifying meatal advancement glandular with release chordi versus snodgrass surgical methods regarding the repair of distal hypospadias. World J Plast Surg. 10:73–77. 2021.PubMed/NCBI View Article : Google Scholar | |
Edan OAA: Urethral mobilization and advancement technique in distal types of hypospadias: Short-term local experience. Ann Pediatr Surgery. 17(60)2021. | |
Noureldin YA, Gharib TM, El Attar KA, El Karamany TM and Al Adl AM: Extended TIP vs standard TIP for primary distal hypospadias repair: Randomized study for comparing functional and cosmetic outcomes. Scand J Urol. 55:466–473. 2021.PubMed/NCBI View Article : Google Scholar | |
Abdelhalim KM, Abdelwahab HA, Abdelgawad E, Kadry AM and Sherief MH: Predictors of successful outcome of tubularized incised plate for primary distal hypospadias repair. Afr J Urol. 27(164)2021.PubMed/NCBI View Article : Google Scholar | |
Shoukry A, Abbas A, Abdelwahab M, Ghoneima W, Shouman A, El Ghoneimy M, Morsi H, Badawy H, Eissa M and Aboulela W: Glans-urethral meatus-shaft score and penile parameters as preoperative assessment tools for hypospadias surgery outcome. Afr J Urol. 27(102)2021. | |
Macedo A Jr, Ottoni SL, Di Migueli RDD, de Mattos RM, Garrone G and Leal da Cruz M: A different approach to distal hypospadias repair: The GUD (glandular urethral disassembly) technique. J Pediatr Urol. 17:690.e1–690.e6. 2021.PubMed/NCBI View Article : Google Scholar | |
Özbey H, Ayryan E, Staroverov O and Morozov DA: Anatomical modeling of the foreskin for the reconstruction of glanular hypospadias. J Pediatr Urol. 17:335–337. 2021.PubMed/NCBI View Article : Google Scholar | |
Permana W, Djojodimedjo T and Renaldo J: Tubularized incised plate urethroplasty for megameatus intact prepuce hypospadias variant: First reported case in Indonesia. Int J Surg Case Rep. 80(105698)2021.PubMed/NCBI View Article : Google Scholar | |
Ahmed S, Noureldin YA, Sherif H, Zahran A and Omar R: Cosmetic outcomes of grafted tubularized incised plate urethroplasty in primary distal penile hypospadias: Prospective comparative study with the classic snodgrass repair. Afr J Urol. 27(152)2021. | |
Kızılöz H, Okçelik S and Temel MC: MAGPI under local anaesthesia without catheter as an alternative to standard TIP procedure in distal hypospadias repair. Andrologia. 53(e13949)2021.PubMed/NCBI View Article : Google Scholar | |
Alshammari D and Harper L: Deepithelialized glans reconfiguration (DeGRe) for distal hypospadias repair. J Pediatr Urol. 17:59.e1–59.e8. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhang B, Bi YL and Ruan SS: Application and efficacy of reconstructing forked corpus spongiosum in distal/midshaft hypospadias repair. Asian J Androl. 23:47–51. 2021.PubMed/NCBI View Article : Google Scholar | |
Mohajerzadeh L, Moghadam AD, Tabari AK, Rouzrokh M and Moghimi N: Comparing mathieu and tubularized incised-plate urethroplasties for repairing distal penile hypospadias: A single-center experience with long-term outcome. Iran J Pediatr. 31(e111184)2021. | |
Benson CR, Li G and Brandes SB: Long term outcomes of one-stage augmentation anterior urethroplasty: A systematic review and meta-analysis. Int Braz J Urol. 47:237–250. 2021.PubMed/NCBI View Article : Google Scholar | |
Tessier B, Sfar S, Garnier S, Coffy A, Borrego P, Gaspari L, Paris F and Kalfa N: A cover flap reduces the rate of fistula after urethroplasty whatever the severity of hypospadias. World J Urol. 39:2691–2695. 2021.PubMed/NCBI View Article : Google Scholar | |
Rudin YE, Maruhnenko DV, Rudin AY, Aliev DK, Lagutin GV and Vardak AB: Augmentation of the urethral plate in the glans penis area and the distal urethra-effective method of fistula correction in children with hypospadias. Androl Gen Surg. 22:62–70. 2021. | |
Verma A, Murtaza S, Kundal VK, Sen A and Gali D: Comparison of dartos flap and spongioplasty in snodgrass urethroplasty in distal penile hypospadias. World J Pediatr Surg. 4(e000294)2021.PubMed/NCBI View Article : Google Scholar | |
Naumeri F, Munir MA, Ahmad HM, Sharif M, Awan NU and Butt G: Comparison of urethrocutaneous fistula rate after single dartos and double dartos tubularized incised plate urethroplasty in pediatric hypospadias. Cureus. 13(e13378)2021.PubMed/NCBI View Article : Google Scholar | |
Zhang Y, Chao M, Zhang WP, Tang YM, Chen HC, Zhang KP, Lu RG, Zhang XS and Lou DH: Using Buck's fascia as an integral covering in urethroplasty to restore the anatomical structure of the penis in one-stage hypospadias repair: A multicenter chinese study comprising 1,386 surgeries. Front Pediatr. 9(695912)2021.PubMed/NCBI View Article : Google Scholar | |
Cetin S, Budak FC, Tan MO, Biri H, Sen I, Kupeli AB, Bozkirli I and Gurocak OS: Comparison of corporal plication for the correction of congenital penile curvature in pre-pubertal and post-pubertal patients: Does age matter? Andrologia. 53(e13965)2021.PubMed/NCBI View Article : Google Scholar | |
Kozyrev GV, Manasherova DT and Abdulkarimov GA: Ventral penis curvature correction in children with hypospadias. Urologiia. 74–77. 2021.PubMed/NCBI(In Russian). | |
Zhou G, Xu W, Yin J, Sun J, Yang Z and Li S: Single-stage versus staged interposition urethroplasty for glandular hypospadias with severe penile curvature: 15-Year experience. World J Urol. 40:155–160. 2022.PubMed/NCBI View Article : Google Scholar | |
Furr JR, Wisenbaugh ES and Gelman J: Long-term outcomes for 2-stage urethroplasty: An analysis of risk factors for urethral stricture recurrence. World J Urol. 39:3903–3911. 2021.PubMed/NCBI View Article : Google Scholar | |
Favre GA, Villa SG, Scherñuk J, Tobia IP and Giudice CR: Glans preservation in surgical treatment of distal urethral strictures with dorsal buccal mucosa graft onlay by subcoronal approach. Urology. 152:148–152. 2021.PubMed/NCBI View Article : Google Scholar | |
Mershon JP and Baradaran N: Recurrent anterior urethral stricture: challenges and solutions. Res Rep Urol. 13:237–249. 2021.PubMed/NCBI View Article : Google Scholar | |
Singh J: Urethrocutaneous fistula repair following hypospadias surgery using the PATIO technique for small fistulae: A single centre experience. J Pediatr Urol. 18:60.e1–60.e7. 2022.PubMed/NCBI View Article : Google Scholar | |
Bar-Yosef Y, Ben-Chaim J, Ekstein M, Ben-David R, Savin Z, Yossepowitch O, Mano R and Dekalo S: Concomitant repair of meatal stenosis and urethral fistula does not increase the risk of fistula recurrence post hypospadias surgery. Urology. 160:187–190. 2022.PubMed/NCBI View Article : Google Scholar | |
Chatterjee US, Basu AK and Bhaumik K: Needling for suture track fistula. J Indian Assoc Pediatr Surg. 26:203–205. 2021.PubMed/NCBI View Article : Google Scholar | |
Shirazi M, Chowdhury U, Ahmed F, Rajabalian MB, Nikbakht HA, Al-Naggar K and Al-Shami E: Optimal clamping time in meatotomy procedure for children with meatal stenosis: Experience with 120 cases. Arch Ital Urol Androl. 93:244–247. 2021.PubMed/NCBI View Article : Google Scholar | |
Shaw NM, Mallahan C, Joshi P, Venkatesan K and Kulkarni S: Novel use of Asopa technique for penile urethrocutaneous fistula repair. Int Urol Nephrol. 53:1127–1133. 2021.PubMed/NCBI View Article : Google Scholar | |
Yadav S, Bamaniya M, Agarwal V, Tomar V, Gupta A and Kumawat G: Dorsal midline incision: A versatile technique for correction of meatal stenosis during hypospadias repair. J Clin Urol. 14:43–46. 2021. | |
Samir M, Mahmoud MA, Azazy S and Tawfick A: Does the suturing technique (continuous versus interrupted) have an impact on the outcome of tubularized incised plate in hypospadias repair with adequate urethral plate? A prospective randomized study. J Pediatr Urol. 17:519.e1–519.e7. 2021.PubMed/NCBI View Article : Google Scholar | |
Spinoit AF, Sinatti C, Lambert E, Pauwaert K, Verla W, van Laecke E and Hoebeke P: How I do it: Buttonholing the preputial hood in hypospadias repair-related ventral skin shortage. J Pediatr Urol. 17:332–334. 2021.PubMed/NCBI View Article : Google Scholar | |
Mohamed Ali Alaraby SO, Abdeljaleel IA, Hamza AA and Elawad Elhassan AE: A comparative study of polydioxanone (PDS) and polyglactin (Vicryl) in hypospadias repair. Afr J Paediatr Surg. 18:53–57. 2021.PubMed/NCBI View Article : Google Scholar | |
Scarpa MG, Codrich D, Iaquinto M, Guida E, Cerrina A and Schleef J: Medium-term outcome after stented and un-stented distal urethroplasty: A retrospective analysis on redo-urethroplasty need and cosmetic results. Actas Actas Urol Esp (Engl Ed). 45:642–647. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhang SY, Han C, Zhou HX, Li P, Ma LF, Tao T, Zhou XG, Tao YD, Zhu WW, Zhao Y, et al: Clinical evaluation of compound chamomile and lidocaine hydrochloride gel for postoperative hypospadias in children. Zhonghua Nan Ke Xue. 27:815–818. 2021.PubMed/NCBI(In Chinese). | |
Doluoglu OG, Yıldız Y, Tokat E, Ozgur BC, Kılınc MF, Inan MA, Gonul II and Hoscan MB: The histopathological effect of aloe vera on the wound healing process in a surgically created tubularized incised plate urethroplasty model on rats. J Invest Surg. 35:1062–1066. 2022.PubMed/NCBI View Article : Google Scholar | |
Oley MH, Oley MC, Iskandar AAA, Toreh C, Tulong MT and Faruk M: Hyperbaric oxygen therapy for reconstructive urology wounds: A case series. Res Rep Urol. 13:841–852. 2021.PubMed/NCBI View Article : Google Scholar | |
Anand S, Krishnan N and Bajpai M: Utility and safety of hyperbaric oxygen therapy as a rescue treatment in complicated cases of hypospadias: A systematic review and meta-analysis. J Pediatr Urol. 18:39–46. 2022.PubMed/NCBI View Article : Google Scholar | |
Anand S: Single-diaper, double-diaper, or no diaper: Does it make any difference following the repair of hypospadias? J Pediatr Urol. 17(885)2021.PubMed/NCBI View Article : Google Scholar | |
Donnelly L, Feustel PJ, Cangero T and Kogan B: Postoperative pediatric urology opioid prescriptions at a tertiary academic medical center. J Pediatr Urol. 17:633.e1–633.e6. 2021.PubMed/NCBI View Article : Google Scholar | |
Cornwell LB, Campbell PC, Ewing E and Swords KA: Children undergoing outpatient complex penile surgery and hypospadias repair may not require opioid analgesics. J Pediatr Surg. 57:678–682. 2022.PubMed/NCBI View Article : Google Scholar | |
Basin MF, Baker ZG, Trabold M, Zhu T, Kelley-Quon LI, Bhaskar N, Vazirani R, Chen J and Kokorowski PJ: The impact of patient age and procedure type on postoperative opioid use following ambulatory pediatric urologic procedures. Pediatr Surg Int. 37:1127–1133. 2021.PubMed/NCBI View Article : Google Scholar | |
Ji F, Tang H, Wu C, Chen L, Wang H and Yan B: Predictive value of C-reactive protein for early postoperative complications in children after hypospadias surgery. Front Pediatr. 9(690863)2021.PubMed/NCBI View Article : Google Scholar | |
Karakaya AE, Güler AG and Doǧan AB: Dressing or not after tubularized incised plate urethroplasty. Urol Int. 105:1029–1033. 2021.PubMed/NCBI View Article : Google Scholar | |
Esposito C, Coppola V, Del Conte F, Cerulo M, Esposito G, Crocetto F, Castagnetti M, Calignano A and Escolino M: Evaluation of a new tubular finger oxygen-enriched oil inside-coated dressing device in pediatric patients undergoing distal hypospadias repair: A prospective randomized clinical trial part II. Front Pediatr. 9(638406)2021.PubMed/NCBI View Article : Google Scholar | |
Esposito C, Del Conte F, Cerulo M, Coppola V, Esposito G, Ricciardi E, Crocetto F, Castagnetti M, Calignano A and Escolino M: Evaluation of efficacy of oxygen-enriched oil-based gel dressing in patients who underwent surgical repair of distal hypospadias: A prospective randomised clinical trial. World J Urol. 39:2205–2215. 2021.PubMed/NCBI View Article : Google Scholar | |
Anand S: Tissue glue-based dressings following hypospadias repair: A game-changer or a useless gimmick! J Pediatr Urol. 17:679–680. 2021.PubMed/NCBI View Article : Google Scholar | |
Elsayem K, Darwish AS, AbouZeid AA, Kamel N, Dahab MM and El-Naggar O: Autologous platelet gel improves outcomes in tubularized incised plate repair of hypospadias. J Pediatr Surg. 57:488–491. 2022.PubMed/NCBI View Article : Google Scholar | |
Murakami H, Seo S, Ochi T, Yazaki Y, Takeda M and Yamataka A: A useful tip for preventing surgical site infections after hypospadias repair. A single surgeon's experience of 376 cases. Afr J Paediatr Surg. 18:5–8. 2021.PubMed/NCBI View Article : Google Scholar | |
Canon SJ, Smith JC, Sullivan E, Patel A and Zamilpa I: Comparative analysis of perioperative prophylactic antibiotics in prevention of surgical site infections in stented, distal hypospadias repair. J Pediatr Urol. 17:256.e1–256.e5. 2021.PubMed/NCBI View Article : Google Scholar | |
Kim JK, Shiff M, Chua ME, Zu'bi F, Ming JM, Pokarowski M and Farhat WA: Time to event analysis for post-hypospadias repair complications: A single-surgeon experience. World J Urol. 39:3913–3919. 2021.PubMed/NCBI View Article : Google Scholar | |
Arslan Alıcı Ç, Karkın EB and Tokar B: An atypical complication after hypospadias repair: A combined dorsal and lateral subcoronal urethrocutaneous fistulas. Andrologia. 54(e14276)2022.PubMed/NCBI View Article : Google Scholar | |
Shirazi M, Haghpanah A, Dehghani A, Haghpanah S, Ghahartars M and Rahmanian M: Comparison of post-urethroplasty complication rates in pediatric cases with hypospadias using Vicryl or polydioxanone sutures. Asian J Urol. 9:165–169. 2022.PubMed/NCBI View Article : Google Scholar | |
Karabulut R, Turkyilmaz Z, Atan A, Kaya C and Sonmez K: What are the factors affecting glanular dehiscence after hypospadias surgery? Actas Urol Esp (Engl Ed). 46:4–15. 2022.PubMed/NCBI View Article : Google Scholar : (In English, Spanish). | |
Nguyen S, Durbin-Johnson B and Kurzrock EA: Reoperation after hypospadias repair: Long-term analysis. J Urol. 205:1778–1784. 2021.PubMed/NCBI View Article : Google Scholar | |
Ru W, Tang D, Wu D, Tao C, Chen G, Wei J, Tian H and Shu Q: Identification of risk factors associated with numerous reoperations following primary hypospadias repair. J Pediatr Urol. 17:61.e1–61.e5. 2021.PubMed/NCBI View Article : Google Scholar | |
Snodgrass W and Bush N: Recurrent ventral curvature after proximal TIP hypospadias repair. J Pediatr Urol. 17:222.e1–222.e5. 2021.PubMed/NCBI View Article : Google Scholar | |
Ben-David R, Kupershmidt A, Dekalo S, Herzberg H, Mano R, Dubi-Sobol A, Ben-Chaim J and Bar-Yosef Y: Dorsal penile curvature and megameatus intact prepuce hypospadias: A common association in a rare variant of hypospadias. J Pediatr Urol. 17:517.e1–517.e4. 2021.PubMed/NCBI View Article : Google Scholar | |
Spinoit AF, Waterschoot M, Sinatti C, Abbas T, Callens N, Cools M, Hamid R, Hanna MK, Joshi P, Misseri R, et al: Fertility and sexuality issues in congenital lifelong urology patients: male aspects. World J Urol. 39:1013–1019. 2021.PubMed/NCBI View Article : Google Scholar | |
Varea-Malo R, Martínez Revuelta D, Campos-Juanatey F, Calleja Hermosa P and Correas Gómez MA: Long-term undesirable consequences of penile skin island flap to correct penoescrotal transposition: A case report and review of literature. Case Rep Urol. 2021(6656540)2021.PubMed/NCBI View Article : Google Scholar | |
Kumar S, Mittal A, Panwar VK and Mandal AK: Laser epilation of luminal hair following skin graft urethroplasty for hypospadias: The hair snare. BMJ Case Rep. 14(e244123)2021.PubMed/NCBI View Article : Google Scholar | |
Özbey H and Morozov D: Hypospadias surgery, erectile dysfunction and the distal ligament. J Pediatr Urol. 17:592–593. 2021.PubMed/NCBI View Article : Google Scholar | |
Husmann DA: Erectile dysfunction in patients undergoing multiple attempts at hypospadias repair: Etiologies and concerns. J Pediatr Urol. 17:166.e1–166.e7. 2021.PubMed/NCBI View Article : Google Scholar | |
Chapman DW, Bekkema J and Rourke K: Urinary symptom nonresponse (‘LUTS failure’) after urethroplasty: Incidence and Associations. J Urol. 206:986–993. 2021.PubMed/NCBI View Article : Google Scholar | |
Favre G, Gil S, Carminatti T, Tobia I and Giudice C and Giudice C: Predictors of complex urethral surgery in anterior urethral stricture disease. Arch Esp Urol. 74:547–553. 2021.PubMed/NCBI | |
Faraj S, Loubersac T, Bouchot O, Heloury Y and Leclair MD: Adults with previous hypospadias surgery during childhood: Beware of bulbar strictures. J Pediatr Urol. 18:4.e1–4.e8. 2022.PubMed/NCBI View Article : Google Scholar | |
Ali D and Hanna MK: Symptomatic corpus spongiosum defect in adolescents and young adults who underwent distal hypospadias repair during childhood. J Pediatr Urol. 17:814.e1–814.e5. 2021.PubMed/NCBI View Article : Google Scholar | |
Tack LJW, Springer A, Riedl S, Tonnhofer U, Hiess M, Weninger J, Mahmoud A, Van Laecke E, Hoebeke P, Cools M and Spinoit AF: Adolescent and young adult urogenital outcome following childhood hypospadias repair: Perfection revisited. J Urol. 206:734–744. 2021.PubMed/NCBI View Article : Google Scholar | |
Godfrey LM: Mental health outcomes among individuals with 46,XY disorders of sex development: A systematic review. J Health Psychol. 26:40–59. 2021.PubMed/NCBI View Article : Google Scholar | |
Sembiring G and Sigumonrong Y: Efficacy of preoperative testosterone therapy in hypospadias: A systematic review and meta-analysis. Ann Pediatr Surg. 17(56)2021. | |
Lucas-Herald AK, Montezano AC, Alves-Lopes R, Haddow L, Alimussina M, O'Toole S, Flett M, Lee B, Amjad SB, Steven M, et al: Vascular dysfunction and increased cardiovascular risk in hypospadias. Eur Heart J. 43:1832–1845. 2022.PubMed/NCBI View Article : Google Scholar | |
Alizadeh F, Amraei M, Haghdani S and Honarmand A: The effect of caudal epidural block on the surgical complications of hypospadias repair in children aged 6 to 35 months: A randomized controlled trial. J Pediatr Urol. 18:59.e1–59.e6. 2022.PubMed/NCBI View Article : Google Scholar | |
Koul A, Shukla D, Aggrawal SK and Sethi N: Incidence of urethrocutaneous fistula following distal hypospadias repair with and without caudal epidural block: A randomized pilot study. J Pediatr Urol. 18:58.e1–58.e7. 2022.PubMed/NCBI View Article : Google Scholar | |
Adler AC, Chandrakantan A, Lee AD, Koh CJ, Janzen NK and Austin PF: Effect of caudal vs penile block on the incidence of hypospadias complications following primary repairs: A retrospective cohort study. J Urol. 205:1454–1459. 2021.PubMed/NCBI View Article : Google Scholar | |
Osmani F, Ferrer F and Barnett NR: Regional anesthesia for ambulatory pediatric penoscrotal procedures. J Pediatr Urol. 17:836–844. 2021.PubMed/NCBI View Article : Google Scholar | |
Routh JC: Caudal blocks and hypospadias repair complications-much ado about nothing or the real deal? J Urol. 205:1252–1253. 2021.PubMed/NCBI View Article : Google Scholar | |
Elsonbaty M, Abdullah S and Elsonbaty A: Lung ultrasound assisted comparison of volume effects of fluid replacement regimens in pediatric patients undergoing penile hypospadias repair: A randomized controlled trial. Anesth Pain Med. 11(e115152)2021.PubMed/NCBI View Article : Google Scholar | |
Kandirici A, Mutlu M and Yiğit D: Does block anesthesia used in hypospadias surgery increase complication rates? İzmir Dr Behçet Uz Çocuk Hast Dergis. 11:328–332. 2021. | |
Sisay A, Girma B, Negusie T, Abdi S, Horsa B and Ayele K: Inadvertent life-threatening total spinal anesthesia following caudal block in a preschool child underwent urologic surgery: A rare case report. Int J Surg Case Rep. 88(106541)2021.PubMed/NCBI View Article : Google Scholar | |
Ponde V, Singh N, Nair A, Ongaigui CJ and Nagdev T: Comparison of landmark-guided, nerve stimulation-guided, and ultrasound-guided techniques for pediatric caudal epidural anesthesia: A prospective randomized controlled trial. Clin J Pain. 38:114–118. 2021.PubMed/NCBI View Article : Google Scholar | |
Ahmed WAI, Shokier MHEHAEW, Kasem AAA, El Aziz MHA and Saed SGA: Comparative study between ultrasound-guided pudendal nerve block and caudal epidural block anesthesia in children undergoing hypospadias surgery. Ain-Shams J Anesthesiol. 13(50)2021.PubMed/NCBI View Article : Google Scholar | |
Wang Y, Jia YP, Zhao LY, He QJ, Qi JL, Zhou R, Yang T, Zhao ZX and Wei HQ: Effects of three different doses of dexmedetomidine and ropivacaine on analgesia and the stress response in hypospadias surgery: A randomized trial. Front Pharmacol. 12(612216)2021.PubMed/NCBI View Article : Google Scholar | |
Hassan AH, Amer IA and Abdelkareem AM: Comparative study between different additives to levobupivacaine in caudal block for postoperative pain management in pediatrics undergoing hypospadias repair: Randomized controlled study. Egypt J Hosp Med. 83:1120–1128. 2021. | |
Karami T, Hoshyar H and Tavana AM: Comparing caudal block and penile block using rectal acetaminophen in postoperative analgesia of hypospadias repair: A randomized clinical trial study. Int J Surg Open. 29:9–13. 2021. | |
Goel HK, Tirthraj CM, Kabra S, Gahlawat S, Sharma U and Sood R: Factors affecting outcome of adult hypospadias single stage repair: A prospective observational study. Turk J Urol. 47:420–426. 2021.PubMed/NCBI View Article : Google Scholar | |
Abbas TO and Ali M: Scrotal base distance: A new key genital measurement in males with hypospadias and cryptorchidism. Curr Urol. 15:214–218. 2021.PubMed/NCBI View Article : Google Scholar | |
Sennert M, Wirmer J and Hadidi AT: Preoperative glans & penile dimensions in different hypospadias grades. J Pediatr Urol. 18:47–53. 2022.PubMed/NCBI View Article : Google Scholar | |
Abbas TO: Evaluation of penile curvature in patients with hypospadias; gaps in the current practice and future perspectives. J Pediatr Urol. 18:151–159. 2022.PubMed/NCBI View Article : Google Scholar | |
Abbas TO: The rising need for preoperative objective quantification of curvature in patients with hypospadias. J Pediatr Urol. 17:599–600. 2021.PubMed/NCBI View Article : Google Scholar | |
Fernandez N, Flórez-Valencia L, Prada JG, Chua M and Villanueva C: Standardization of penile angle estimation with a semi-automated algorithm. J Pediatr Urol. 17:226.e1–226.e6. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhao Z, Liu GC, Zhang LY, Fu W, Jia W and Hu JH: Mean microvessel density of the prepuce and its relationship with the severity of hypospadias and early postoperative complications. Zhonghua Nan Ke Xue. 27:725–728. 2021.PubMed/NCBI(In Chinese). | |
Li K, Zhang X, Yan G, Zheng W and Zou Y: Prenatal diagnosis and classification of fetal hypospadias: The role and value of magnetic resonance imaging. J Magn Reson Imaging. 53:1862–1870. 2021.PubMed/NCBI View Article : Google Scholar | |
Chaudhary G, Yhoshu E, Chauhan U, Ahmed I, Gupta MK, Piplani R and Balija SS: Anatomical study of hypospadias penis using magnetic resonance imaging in children. J Pediatr Urol. 18:57.e1–57.e7. 2022.PubMed/NCBI View Article : Google Scholar | |
Fernandez N, Lorenzo AJ, Rickard M, Chua M, Pippi-Salle JL, Perez J, Braga LH and Matava C: Digital pattern recognition for the identification and classification of hypospadias using artificial intelligence vs experienced pediatric urologist. Urology. 147:264–269. 2021.PubMed/NCBI View Article : Google Scholar | |
Dai LN, He R, Wu SF, Zhao HT and Sun J: Surgical treatment for prostatic utricle cyst in children: A single-center report of 15 patients. Int J Urol. 28:689–694. 2021.PubMed/NCBI View Article : Google Scholar | |
Abbas TO: The plate objective scoring tool (POST): Further reflections and extended applications. Res Rep Urol. 13:783–791. 2021.PubMed/NCBI View Article : Google Scholar | |
D'Oro A, Chan YY, Rosoklija I, Meyer T, Shannon R, Johnson EK, Liu DB, Gong EM, Maizels M, Matoka DJ, et al: Association between intra-operative meatal mismatch and urethrocutaneous fistula development in hypospadias repair. J Pediatr Urol. 17:223.e1–223.e8. 2021.PubMed/NCBI View Article : Google Scholar | |
Gopal M: Ano-scrotal distance (ASD): Is it a marker for the severity of chordee? J Pediatr Urol. 17:672–673. 2021.PubMed/NCBI View Article : Google Scholar | |
Yeşildal C, Yilmaz Ö, Akan S, Küçükodaci Z, Yenigürbüz S and Ediz C: Is primary adult hypospadiatic prepuce different from healthy prepuce in terms of microvascular density and androgen-estrogen-progesterone receptors? Andrologia. 53(e13857)2021.PubMed/NCBI View Article : Google Scholar | |
Seleim HM: Topographic labeling of glans penis and corpus spongiosum when planning surgery for distal hypospadias. Res Rep Urol. 13:167–173. 2021.PubMed/NCBI View Article : Google Scholar | |
Abdullaev Z, Agzamkhodjaev S, Chung JM and Lee SD: Risk factors for fistula recurrence after urethrocutaneous fistulectomy in children with hypospadias. Turk J Urol. 47:237–241. 2021.PubMed/NCBI View Article : Google Scholar | |
Özbey H, Devecioğlu D and Staroverov O: A closer look at iatrogenic hypospadias. Andrologia. 53(e13803)2021.PubMed/NCBI View Article : Google Scholar | |
Gao F, Gong C and Li L: Advance in research on the role of MAMLD1 gene in disorders of sex development. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 38:912–916. 2021.PubMed/NCBI View Article : Google Scholar : (In Chinese). | |
Ibba A, Del Pistoia M, Balsamo A, Baronio F, Capalbo D, Russo G, DE Sanctis L and Bizzarri C: Differences of sex development in the newborn: From clinical scenario to molecular diagnosis. Minerva Pediatr (Torino). 73:606–620. 2021.PubMed/NCBI View Article : Google Scholar | |
Nassau DE, Best JC, Cohen J, Gonzalez DC, Alam A and Ramasamy R: Androgenization in Klinefelter syndrome: Clinical spectrum from infancy through young adulthood. J Pediatr Urol. 17:346–352. 2021.PubMed/NCBI View Article : Google Scholar | |
Nordenskjöld A and Holmdahl G: Role of genetic counseling for patients with hypospadias and their families. Eur J Pediatr Surg. 31:492–496. 2021.PubMed/NCBI View Article : Google Scholar | |
Fendereski K, Carey J, Timme K, Hayes K, Robnett J and Schaeffer A: 46 XY undervirulized male DSD: Reporting a patient with prenatally diagnosed disorder/difference of sex development (DSD) with heterozygous LHCGR mutations. Urol Case Rep. 41(101971)2021.PubMed/NCBI View Article : Google Scholar | |
Alfei E, Cattaneo E, Spaccini L, Iascone M, Veggiotti P and Doneda C: Progressive clinical and neuroradiological findings in a child with BCL11B missense mutation: Expanding the phenotypic spectrum of related disorder. Neuropediatrics. 53:283–286. 2022.PubMed/NCBI View Article : Google Scholar | |
Li M, Che F, Qiu S and Wang Z: Identification of a novel variant of SRD5A2 gene in a child featuring steroid 5α-reductase type 2 deficiency. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 38:1233–1236. 2021.PubMed/NCBI View Article : Google Scholar : (In Chinese). | |
Strong A, March ME, Cardinale CJ, Kim SE, Merves J, Whitworth H, Raffini L, Larosa C, Copelovitch L, Hou C, et al: A novel MBTPS2 variant associated with BRESHECK syndrome impairs sterol-regulated transcription and the endoplasmic reticulum stress response. Am J Med Genet A. 188:463–472. 2022.PubMed/NCBI View Article : Google Scholar | |
Arsov T, Kelecic J, Frkovic SH, Sestan M, Kifer N, Andrews D, Adamski M, Jelusic M and Cook MC: Expanding the clinical spectrum of pathogenic variation in NR2F2: Asplenia. Eur J Med Genet. 64(104347)2021.PubMed/NCBI View Article : Google Scholar | |
Thomas MM, Ashaat EA, Otaify GA, Ismail S, Essawi ML, Abdel-Hamid MS, Hassan HA, Alsaiedi SA, Aglan M, El Ruby MO and Temtamy S: First report of two egyptian patients with desbuquois dysplasia due to homozygous CANT1 mutations. Mol Syndromol. 12:279–288. 2021.PubMed/NCBI View Article : Google Scholar | |
Bouhouche A, Albaroudi N, El Alaoui MA, Askander O, Habbadi Z, El Hassani A, Iraqi H, El Fahime E and Belmekki M: Identification of the novel SDR42E1 gene that affects steroid biosynthesis associated with the oculocutaneous genital syndrome. Exp Eye Res. 209(108671)2021.PubMed/NCBI View Article : Google Scholar | |
Luo Q, Zhang Q, Shen J, Guan W, Li M, Zhang J and Tan Z: Expanding mutational spectrum of HRAS by a patient with schimmelpenning-feuerstein-mims syndrome. J Dermatol. 48:1273–1276. 2021.PubMed/NCBI View Article : Google Scholar | |
Akramov NR, Shavaliev RF and Osipova IV: .: New mutation in WT1 gene in a boy with an incomplete form of Denys-Drash syndrome: A CARE-compliant case report. Medicine (Baltimore). 100(e25864)2021.PubMed/NCBI View Article : Google Scholar | |
Elghezal H, Alfayez K, Ben Abdallah I, Alfares A, Almazyad A, Al Jasser A, Almobadel N, Alsuhaibani O and Alhashem A: Hypospadias in ring X syndrome. Eur J Med Genet. 64(104225)2021.PubMed/NCBI View Article : Google Scholar | |
Ravirajendran S, Palaniyandi V, Arora A, Ramanan V and Kumaresan N: Mullerian remnants presenting as a pelvic cyst in a young adult with 45X0/46XY mixed gonadal dysgenesis. Urol Ann. 13:76–79. 2021.PubMed/NCBI View Article : Google Scholar | |
Correya M, Babu R, Archana B and Ravirajendiran S: Disorders of sexual differentiation: Report of two rare cases. Indian J Pathol Microbiol. 64:390–393. 2021.PubMed/NCBI View Article : Google Scholar | |
Chen L, Huang H, Zhang H, Zhu G and Zhu M: Three cases of 3β-hydroxysteroid dehydrogenase deficiency: Clinical analysis. Adv Clin Exp Med. 30:289–299. 2021.PubMed/NCBI View Article : Google Scholar | |
Saida K, Fukuda T, Scott DA, Sengoku T, Ogata K, Nicosia A, Hernandez-Garcia A, Lalani SR, Azamian MS, Streff H, et al: OTUD5 variants associated with X-linked intellectual disability and congenital malformation. Front Cell Dev Biol. 9(631428)2021.PubMed/NCBI View Article : Google Scholar | |
Çiftci N, Kayaş L, Çamtosun E and Akıncı A: 46,XY sex development defect due to a novel homozygous (splice site) c.673_1G>C variation in the HSD17B3 gene: Case report. J Clin Res Pediatr Endocrinol. 14:233–238. 2022.PubMed/NCBI View Article : Google Scholar | |
Laan M, Kasak L, Timinskas K, Grigorova M, Venclovas Č, Renaux A, Lenaerts T and Punab M: NR5A1 c.991-1G>C splice-site variant causes familial 46,XY partial gonadal dysgenesis with incomplete penetrance. Clin Endocrinol (Oxf). 94:656–666. 2021.PubMed/NCBI View Article : Google Scholar | |
Gerber JA, Sheth KR and Austin PF: Robinow syndrome: Genital analysis, genetic heterogeneity, and associated psychological impact. Am J Med Genet A. 185:3601–3605. 2021.PubMed/NCBI View Article : Google Scholar | |
Sheppard SE, Barrett B, Muraresku C, McKnight H, De Leon DD, Lord K and Ganetzky R: Heterozygous recurrent HNF4A variant p.Arg85Trp causes Fanconi renotubular syndrome 4 with maturity onset diabetes of the young, an autosomal dominant phenocopy of Fanconi Bickel syndrome with colobomas. Am J Med Genet A. 185:566–570. 2021.PubMed/NCBI View Article : Google Scholar | |
Tripolszki K, Sasaki E, Hotakainen R, Kassim AH, Pereira C, Rolfs A, Bauer P, Reardon W and Bertoli-Avella AM: An X-linked syndrome with severe neurodevelopmental delay, hydrocephalus, and early lethality caused by a missense variation in the OTUD5 gene. Clin Genet. 99:303–308. 2021.PubMed/NCBI View Article : Google Scholar | |
Hage M, Drui D, Francou B, Mercier S, Guiochon-Mantel A, Belaisch-Allart J, Péréon Y, Cazabat L, De Mazancourt P and Raffin-Sanson ML: Structural analysis of the impact of a novel androgen receptor gene mutation in two adult patients with mild androgen insensitivity syndrome. Andrologia. 53(e13865)2021.PubMed/NCBI View Article : Google Scholar | |
Basa M, Vukovic R, Sarajlija A, Milenkovic T, Djordjevic M, Vucetic B and Martic J: Ambiguous genitalia and lissencephaly in A 46,XY neonate with a novel variant of aristaless gene. Acta Endocrinol (Buchar). 17:402–405. 2021.PubMed/NCBI View Article : Google Scholar | |
Kherouatou-Chaoui N, Chellat-Rezgoune D, Rezgoune ML, Mc Elreavey K, Touabti LS, Abadi N and Satta D: SRY and NR5A1 gene mutation in Algerian children and adolescents with DSD and testicular dysgenesis. Afr Health Sci. 21:1491–1497. 2021.PubMed/NCBI View Article : Google Scholar | |
Chen J, Cui X, Li A, Li G and Sun F: Association of a GATA binding protein 4 polymorphism with the risk of hypospadias in the Chinese children. Urol Int. 105:1018–1023. 2021.PubMed/NCBI View Article : Google Scholar | |
Wong YS, Pang KKY and Tam YH: Surgery in Chinese children affected by 45,X/46,XY disorders of sex development: A 20-year experience in a single center. J Pediatr Surg. 57:1398–1403. 2022.PubMed/NCBI View Article : Google Scholar | |
Deng F, Zhao J, Jia W, Fu K, Zuo X, Huang L, Wang N, Xia H, Zhang Y, Fu W and Liu G: Increased hypospadias risk by GREM1 rs3743104[G] in the southern Han Chinese population. Aging (Albany NY). 13:13898–13908. 2021.PubMed/NCBI View Article : Google Scholar | |
Siregar S, Sibarani J, Noegroho BS, Firmansyah I and Maskoen AM: Polymorphism of PvuII, Xba1, and SNP 12 estrogen receptor 1 (ESR1) in hipospadias patients at tertiary hospital center. Res Rep Urol. 13:105–110. 2021.PubMed/NCBI View Article : Google Scholar | |
Saraç M, Canpolat Ş, Önalan Etem E, Tektemur A, Tartar T, Bakal U and Kazez A: The role of sonic hedgehog homologue signal pathway in hypospadias aetiology. J Pediatr Urol. 17:630.e1–630.e7. 2021.PubMed/NCBI View Article : Google Scholar | |
Tenenbaum-Rakover Y, Admoni O, Elias-Assad G, London S, Noufi-Barhoum M, Ludar H, Almagor T, Zehavi Y, Sultan C, Bertalan R, et al: The evolving role of whole-exome sequencing in the management of disorders of sex development. Endocr Connect. 10:620–629. 2021.PubMed/NCBI View Article : Google Scholar | |
Ea V, Bergougnoux A, Philibert P, Servant-Fauconnet N, Faure A, Breaud J, Gaspari L, Sultan C, Paris F and Kalfa N: How far should we explore hypospadias? Next-generation sequencing applied to a large cohort of hypospadiac patients. Eur Urol. 79:507–515. 2021.PubMed/NCBI View Article : Google Scholar | |
Schmidt J, Schreiber G, Altmüller J, Thiele H, Nürnberg P, Li Y, Kaulfuß S, Funke R, Wilken B, Yigit G and Wollnik B: Familial cleft tongue caused by a unique translation initiation codon variant in TP63. Eur J Hum Genet. 30:211–218. 2022.PubMed/NCBI View Article : Google Scholar | |
Ding Y, Cao BY, Su C, Liu M, Chen JJ, Fan LJ and Gong CX: Clinical and genetic analysis of Noonan syndrome in 20 children. Zhonghua Er Ke Za Zhi. 59:588–593. 2021.PubMed/NCBI View Article : Google Scholar : (In Chinese). | |
Lourenço CSFP, Carriço AL and Valente FMDS: Prenatal diagnosis of aberrant right subclavian artery: Association with genetic abnormalities. Rev Bras Ginecol Obstet. 43:452–456. 2021.PubMed/NCBI View Article : Google Scholar | |
Konishi A, Ida S, Matsui F, Etani Y and Kawai M: Male assignment in 5α-reductase type 2 deficiency with female external genitalia. Pediatr Int. 63:592–594. 2021.PubMed/NCBI View Article : Google Scholar | |
Rjiba K, Ayech H, Kraiem O, Slimani W, Jelloul A, Ben Hadj Hmida I, Mahdhaoui N, Saad A and Mougou-Zerelli S: Disorders of sex development in Wolf-Hirschhorn syndrome: A genotype-phenotype correlation and MSX1 as candidate gene. Mol Cytogenet. 14(12)2021.PubMed/NCBI View Article : Google Scholar | |
Yuri P, Gunadi Lestari RP, Fardilla FP and Dachlan I: Expression of mRNA vascular endothelial growth factor in hypospadias patients. BMC Urol. 21(163)2021.PubMed/NCBI View Article : Google Scholar | |
Kong X, Luo J, Xiang H, Wang S, Shen L, Long C, Liu F, Lin T, He D, Liu X and Wei GH: Expression of Mafb is down-regulated in the foreskin of children with hypospadias. J Pediatr Urol. 17:70.e1–70.e6. 2021.PubMed/NCBI View Article : Google Scholar | |
Spinder N, Bergman JEH, van Tongeren M, Boezen HM, Kromhout H and de Walle HEK: Maternal occupational exposure to endocrine-disrupting chemicals and urogenital anomalies in the offspring. Hum Reprod. 37:142–151. 2021.PubMed/NCBI View Article : Google Scholar | |
Rodprasert W, Toppari J and Virtanen HE: Endocrine disrupting chemicals and reproductive health in boys and men. Front Endocrinol (Lausanne). 12(706532)2021.PubMed/NCBI View Article : Google Scholar | |
Mattiske DM and Pask AJ: Endocrine disrupting chemicals in the pathogenesis of hypospadias; developmental and toxicological perspectives. Curr Res Toxicol. 2:179–191. 2021.PubMed/NCBI View Article : Google Scholar | |
Laws MJ, Neff AM, Brehm E, Warner GR and Flaws JA: Endocrine disrupting chemicals and reproductive disorders in women, men, and animal models. Adv Pharmacol. 92:151–190. 2021.PubMed/NCBI View Article : Google Scholar | |
Stukenborg JB, Mitchell RT and Söder O: Endocrine disruptors and the male reproductive system. Best Pract Res Clin Endocrinol Metab. 35(101567)2021.PubMed/NCBI View Article : Google Scholar | |
Schiesaro MG, Amato AML, Maneschi C, Sciabica V, Pigatto E and Sanna M: The male reproductive system and endocrine disruptors. Endocr Metab Immune Disord Drug Targets. 22:686–703. 2022.PubMed/NCBI View Article : Google Scholar | |
Wu Y, Wang J, Wei Y, Chen J, Kang L, Long C, Wu S, Shen L and Wei G: Contribution of prenatal endocrine-disrupting chemical exposure to genital anomalies in males: The pooled results from current evidence. Chemosphere. 286(131844)2022.PubMed/NCBI View Article : Google Scholar | |
Gaspari L, Tessier B, Paris F, Bergougnoux A, Hamamah S, Sultan C and Kalfa N: endocrine-disrupting chemicals and disorders of penile development in humans. Sex Dev. 15:213–228. 2021.PubMed/NCBI View Article : Google Scholar | |
Huang X, Chen J, Zeng D, Lin Z, Herbert C, Cottrell L, Liu L, Ash A and Wang B: The association between ambient air pollution and birth defects in five major ethnic groups in Liuzhou, China. BMC Pediatr. 21(232)2021.PubMed/NCBI View Article : Google Scholar | |
Xing Z, Zhang S, Jiang YT, Wang XX and Cui H: Association between prenatal air pollution exposure and risk of hypospadias in offspring: A systematic review and meta-analysis of observational studies. Aging (Albany NY). 13:8865–8879. 2021.PubMed/NCBI View Article : Google Scholar | |
Bougnères P, Porcher R, Esterle L, Baker D, de la Vaissière A, Meurisse S, Valtat S, Castell AL, Mouriquand P and Valleron AJ: Exploring the risk of hypospadias in children born from mothers living close to a vineyard. PLoS One. 16(e0249800)2021.PubMed/NCBI View Article : Google Scholar | |
Mesquita I, Lorigo M and Cairrao E: Update about the disrupting-effects of phthalates on the human reproductive system. Mol Reprod Dev. 88:650–672. 2021.PubMed/NCBI View Article : Google Scholar | |
Soyer-Gobillard MO, Gaspari L, Paris F, Kalfa N, Hamamah S, Courtet P and Sultan C: Prenatal exposure to diethylstilbestrol and multigenerational psychiatric disorders: An informative family. Int J Environ Res Public Health. 18(9965)2021.PubMed/NCBI View Article : Google Scholar | |
Zhang ZC, Liu X, Wei C, Luo J, Shi Y, Lin T, He D and Wei G: Assisted reproductive technologies and the risk of congenital urogenital tract malformations: A systematic review and meta-analysis. J Pediatr Urol. 17:9–20. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhang S, Yue DM, Zhang JY, Huang YH, Li J, Liu S, Chen YL, Li LL, Jiang CZ, Chen ZJ, et al: Maternal exposure to sulfur dioxide before and after conception and the risk of hypospadias in offspring. Ann N Y Acad Sci. 1502:99–109. 2021.PubMed/NCBI View Article : Google Scholar | |
Rouget F, Bihannic A, Cordier S, Multigner L, Meyer-Monath M, Mercier F, Pladys P and Garlantezec R: Petroleum and chlorinated solvents in meconium and the risk of hypospadias: A pilot study. Front Pediatr. 9(640064)2021.PubMed/NCBI View Article : Google Scholar | |
Haghighi MM, Wright CY, Ayer J, Urban MF, Pham MD, Boeckmann M, Areal A, Wernecke B, Swift CP, Robinson M, et al: Impacts of high environmental temperatures on congenital anomalies: A systematic review. Int J Environ Res Public Health. 18(4910)2021.PubMed/NCBI View Article : Google Scholar | |
Gadagbui BK, York RG, Dourson ML, McGinnis PM and Cope RB: Analysis for data-derived extrapolation factors for procymidone. Regul Toxicol Pharmacol. 124(104972)2021.PubMed/NCBI View Article : Google Scholar | |
Lin HC, Guo JM, Ge P and Ou P: Association between prenatal exposure to ambient particulate matter and risk of hypospadias in offspring: A systematic review and meta-analysis. Environ Res. 192(110190)2021.PubMed/NCBI View Article : Google Scholar | |
Akay MA and Yıldız GE: Impact of gestational and parental factors and maternal intake of progesterone on the development of hypospadias: A retrospective case-control study. Taiwan J Obstet Gynecol. 60:894–898. 2021.PubMed/NCBI View Article : Google Scholar | |
Chung EH, Harris BS, Muasher SJ and Kuller JA: The risk of congenital anomalies by fertility treatment modality. Obstet Gynecol Surv. 76:37–47. 2021.PubMed/NCBI View Article : Google Scholar | |
Baskin L, Sinclair A, Derpinghaus A, Cao M, Li Y, Overland M, Aksel S and Cunha GR: Estrogens and development of the mouse and human external genitalia. Differentiation. 118:82–106. 2021.PubMed/NCBI View Article : Google Scholar | |
Wu Y, Yao J wei, Xu L jie, Chen M and Wan L: Risk of congenital malformations in offspring of women using β-blockers during early pregnancy: An updated meta-analysis of observational studies. Br J Clin Pharmacol. 87:806–815. 2021.PubMed/NCBI View Article : Google Scholar | |
Schraw JM, Langlois PH and Lupo PJ: Comprehensive assessment of the associations between maternal diabetes and structural birth defects in offspring: A phenome-wide association study. Ann Epidemiol. 53:14–20.e8. 2021.PubMed/NCBI View Article : Google Scholar | |
Liu Y, Fan L, Wang X and Gong C: Exploring the efficacy of testosterone undecanoate in male children with 5α-reductase deficiency. Pediatr Investig. 5:249–254. 2021.PubMed/NCBI View Article : Google Scholar | |
Li B, Kong I, McGrath M, Farrokhyar F and Braga LH: Evaluating the literature on preoperative androgen stimulation for hypospadias repair using the fragility index-can we trust observational studies? J Pediatr Urol. 17:661–669. 2021.PubMed/NCBI View Article : Google Scholar | |
Concepción-Zavaleta MJ, García-Villasante EJ, Zavaleta-Gutiérrez FE, Barrantes Ticlla JL and Massucco Revoredo FG: Late diagnosis of partial androgen insensitivity syndrome in a peruvian child. Cureus. 13(e16565)2021.PubMed/NCBI View Article : Google Scholar | |
Khokar DS and Patel RV: Can testosterone alter the degree of hypospadias? A comprehensive study. J Indian Assoc Pediatr Surg. 26:38–43. 2021.PubMed/NCBI View Article : Google Scholar | |
Chukwubuike KE: Single dose of testosterone in children with hypospadias: Any effect on the diameter of the glans penis? Afr J Urol. 27(34)2021. | |
D'Oro A, Rosoklija I, Yerkes EB, Lindgren BW, Rychlik K and Cheng EY: Proximal hypospadias and acquired cryptorchidism: Incidence, morphology and potential clinical implications. J Urol. 206:1291–1299. 2021.PubMed/NCBI View Article : Google Scholar | |
Ludorf KL, Benjamin RH, Navarro Sanchez ML, McLean SD, Northrup H, Mitchell LE, Langlois PH, Canfield MA, Scheuerle AE, Scott DA, et al: Patterns of co-occurring birth defects among infants with hypospadias. J Pediatr Urol. 17:64.e1–64.e8. 2021.PubMed/NCBI View Article : Google Scholar | |
Fuchs ME, Halleran DR, Bourgeois T, Sebastião Y, Weaver L, Farrell N, Vilanova-Sánchez A, Gasior A, Halaweish I, Jayanthi VR, et al: Correlation of anorectal malformation complexity and associated urologic abnormalities. J Pediatr Surg. 56:1988–1992. 2021.PubMed/NCBI View Article : Google Scholar | |
de Jesus Escano MR, Mejia Sang ME, Reyes-Mugica M, Colaco M and Fox J: Ovotesticular disorder of sex development: Approach and management of an index case in the dominican republic. Cureus. 13(e18512)2021.PubMed/NCBI View Article : Google Scholar | |
Nelwan D, Mount C, Morganstern B and Chan JT: Infant with severe penoscrotal hypospadias: A complex case of genital ambiguity and mistaken identity. Cureus. 13(e15191)2021.PubMed/NCBI View Article : Google Scholar | |
Ashfaq S, Siddiqui A, Shafiq W and Azmat U: A rare presentation of disorder of sex development. Cureus. 13(e12782)2021.PubMed/NCBI View Article : Google Scholar | |
Rittler M, Campaña H, Heisecke S, Ratowiecki J, Elias D, Gimenez L, Poletta FA, Gili J, Pawluk M, Santos MR, et al: Lethality of birth defects in live born infants categorized by gestational age and birth weight. Am J Perinatol: Oct 11, 2021 (Epub ahead of print). | |
Álvarez-Álvarez A, Costa-Romero M, Suárez Saavedra S, Rial JC, Lois Bermejo AM, García González N and Fernández-Rodríguez H: Dandy-Walker malformation associated with extracranial abnormalities in a newborn. Arch Argent Pediatr. 119:e526–e530. 2021.PubMed/NCBI View Article : Google Scholar : (In Spanish). | |
Viet Nguyen H, Hong Vu T, Quy Hong Q, Quang Pham H and Bich Nguyen N: Hypospadias associated with partial bifid phallus: A case report. Urol Case Rep. 39(101840)2021.PubMed/NCBI View Article : Google Scholar | |
Çelik G, Batu Oto B, Kızılay O, Kılıçarslan O and Toptan HH: An unusual ophthalmic presentation of Wolf-Hirschhorn syndrome. Ophthalmic Genet. 42:326–328. 2021.PubMed/NCBI View Article : Google Scholar | |
Bhatia VP, Mittal AG, Austin PF and Hilliard ME: The hypospadias-specific health-related quality of life conceptual framework: A scoping review of the literature. Qual Life Res. 30:1537–1546. 2021.PubMed/NCBI View Article : Google Scholar | |
Hoare DT, Bekkema J and Rourke KF: Prospective assessment of patient-perceived short-term changes in penile appearance after urethroplasty. Urology. 158:222–227. 2021.PubMed/NCBI View Article : Google Scholar | |
Bhatia VP, Hilliard ME, Austin PF and Mittal AG: Evaluating quality of patient-reported outcome measures in patients with hypospadias. J Pediatr Urol. 17:50–58. 2021.PubMed/NCBI View Article : Google Scholar | |
Chang C, Reifsnyder JE, Fahmy AG and Hanna MK: The adolescent glans penis: Functional and aesthetic issues following childhood hypospadias repair. J Pediatr Urol. 17:609.e1–609.e8. 2021.PubMed/NCBI View Article : Google Scholar | |
Sinatti C, Schechter MY, Spinoit AF and Hoebeke P: Long-term outcome of urethral and genital reconstruction in hypospadias and exstrophy-epispadias complex. Curr Opin Urol. 31:480–485. 2021.PubMed/NCBI View Article : Google Scholar | |
Calleja Hermosa P, Campos-Juanatey F, Varea Malo R, Correas Gómez MÁ and Gutiérrez Baños JL: Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists. Sexual function after anterior urethroplasty: A systematic review. Transl Androl Urol. 10:2554–2573. 2021.PubMed/NCBI View Article : Google Scholar | |
Mallenahalli S, Fang AH, Tong CMC and Dangle PP: A review of literature on long-term outcomes of proximal hypospadias-urinary, sexual, and psychosocial. Curr Sex Health Rep. 13:38–44. 2021. | |
Zhang ZC, Liu X, Chen HS, Shi Y, Lin T, He DW, Wei GH and Luo YT: Analysis of the social and clinical factors affecting the age of children when receiving surgery for hypospadias: A retrospective study of 1611 cases in a single center. Asian J Androl. 23:527–531. 2021.PubMed/NCBI View Article : Google Scholar | |
Bennecke E, Bernstein S, Lee P, van de Grift TC, Nordenskjöld A, Rapp M, Simmonds M, Streuli JC, Thyen U and Wiesemann C: dsd-LIFE Group. Early genital surgery in disorders/differences of sex development: Patients' perspectives. Arch Sex Behav. 50:913–923. 2021.PubMed/NCBI View Article : Google Scholar | |
Bangalore Krishna K, Kogan BA, Mazur T, Hoebeke P, Bogaert G and Lee PA: Individualized care for patients with intersex (differences of sex development): Part 4/5.considering the ifs, whens, and whats regarding sexual-reproductive system surgery. J Pediatr Urol. 17:338–345. 2021.PubMed/NCBI View Article : Google Scholar | |
Cakmak M, Gollu G, Ates U, Ergun E, Khanmammadov F, Sozduyar S, Telli O, Kose K, Dilsiz H, Cakmak A, et al: Hypospadias and the use of the ages and stages questionnaire to evaluate neurodevelopmental status of boys with hypospadias. Eur J Pediatr Surg. 32:274–279. 2022.PubMed/NCBI View Article : Google Scholar | |
van de Grift TC, Rapp M, Holmdahl G, Duranteau L and Nordenskjold A: dsd-LIFE group. Masculinizing surgery in disorders/differences of sex development: Clinician- and participant-evaluated appearance and function. BJU Int. 129:394–405. 2022.PubMed/NCBI View Article : Google Scholar | |
Gul M, Hildorf S and Silay MS: Sexual functions and fertility outcomes after hypospadias repair. Int J Impot Res. 33:149–163. 2021.PubMed/NCBI View Article : Google Scholar | |
Guner E and Kadioglu A: Specific urogenital disease information-revealing male genital votive offerings dedicated to gods in ancient age sanctuary medicine. Arch Esp Urol. 74:239–246. 2021.PubMed/NCBI(In English, Spanish). | |
Buyukunal C, Zeller KA, Emre S and Nakayama DK: The history of surgery in disorders of sexual development. J Pediatr Surg. 56:429–433. 2021.PubMed/NCBI View Article : Google Scholar | |
Baker Z, Bhaskar N, Herbst KW, Hagadorn JI and Kokorowski P: Sample size, power, and risk of misclassification in pediatric urology hospital rankings. J Urol. 206:436–446. 2021.PubMed/NCBI View Article : Google Scholar | |
Maier M, Ebert AK, Baunacke M, Groeben C, Eisenmenger N, Thomas C and Huber J: Health care reality of selected pediatric urologic surgeries in Germany from 2006 to 2019. Urologe A. 60:1291–1303. 2021.PubMed/NCBI View Article : Google Scholar : (In German). | |
Scarberry KA, Gor RA and Kovell RC: Management of the transitional urology patient: The role of the adult reconstructive urologist. Curr Urol Rep. 22(15)2021.PubMed/NCBI View Article : Google Scholar | |
Mahalik S, Pati A and Das K: Awareness of common pediatric surgical entities among practicing indian pediatricians. J Indian Assoc Pediatr Surg. 26:89–93. 2021.PubMed/NCBI View Article : Google Scholar | |
Kharbanda EO, Vazquez-Benitez G, DeSilva MB, Spaulding AB, Daley MF, Naleway AL, Irving SA, Klein NP, Tseng HF, Jackson LA, et al: Developing algorithms for identifying major structural birth defects using automated electronic health data. Pharmacoepidemiol Drug Saf. 30:266–274. 2021.PubMed/NCBI View Article : Google Scholar | |
Wu S, He R, Sun J and Zhao H: Acellular dermal matrix graft for ventral corporal lengthening orthoplasty in 2-stage proximal hypospadias repair. Transl Pediatr. 10:3151–3158. 2021.PubMed/NCBI View Article : Google Scholar | |
Singh A, Anand S, Goel P, Yadav DK and Bajpai M: Can sealing promote healing?: A systematic review and meta-analysis highlighting the adjunctive role of tissue sealant application during urethroplasty for hypospadias. J Pediatr Urol. 17:805–812. 2021.PubMed/NCBI View Article : Google Scholar | |
Wang Y, Wang G, Hou X, Zhao Y, Chen B, Dai J and Sun N: Urethral tissue reconstruction using the acellular dermal matrix patch modified with collagen-binding VEGF in beagle urethral injury models. Biomed Res Int. 2021(5502740)2021.PubMed/NCBI View Article : Google Scholar | |
Morgante D, Radford A, Abbas SK, Ingham E, Subramaniam R and Southgate J: Augmentation of the insufficient tissue bed for surgical repair of hypospadias using acellular matrix grafts: A proof of concept study. J Tissue Eng. 12(2041731421998840)2021.PubMed/NCBI View Article : Google Scholar | |
Tawfeek AM, Mohareb AM, Higazy A, Farouk A, Elsaeed KO, Tawfick A and Radwan A: Isoamyl 2-cyanoacrylate interposition in the urethro-cutaneous fistula repair: A randomized controlled trial. Afr J Urol. 27(94)2021. | |
Shenoy NS, Tiwari C, Gandhi S, Kumbhar V, Joseph V, Basu S, Makan A and Shah H: Efficacy of fibrin sealant as waterproof cover in improving outcome in hypospadias surgery. Afr J Paediatr Surg. 18:215–218. 2021.PubMed/NCBI View Article : Google Scholar | |
Abbas TO, Elawad A, Kareem A, Pullattayil S AK, Ali M and Alnaimi A: Preclinical experiments for hypospadias surgery: Systematic review and quality assessment. Front Pediatr. 9(718647)2021.PubMed/NCBI View Article : Google Scholar | |
Amesty MV, Chamorro CI, López-Pereira P, Martínez-Urrutia MJ, Sanz B, Rivas S, Lobato R and Fossum M: Creation of tissue-engineered urethras for large urethral defect repair in a rabbit experimental model. Front Pediatr. 9(691131)2021.PubMed/NCBI View Article : Google Scholar | |
Palermo CM, Foreman JE, Wikoff DS and Lea I: Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development. Curr Res Toxicol. 2:254–271. 2021.PubMed/NCBI View Article : Google Scholar | |
Alcantara MC, Suzuki K, Acebedo AR, Sakamoto Y, Nishita M, Minami Y, Kikuchi A and Yamada G: Stage-dependent function of Wnt5a during male external genitalia development. Congenit Anom (Kyoto). 61:212–219. 2021.PubMed/NCBI View Article : Google Scholar | |
Xiang H, Wang S, Kong X, Yu Y, Shen L, Long C, Liu X and Wei GH: c-Fos is upregulated in the genital tubercle of DEHP-induced hypospadiac rats and the prepuce of patients with hypospadias. Syst Biol Reprod Med. 67:193–200. 2021.PubMed/NCBI View Article : Google Scholar | |
Feng X, Huang E, Gao Y, Zhang Y and Zhou Y: The effects of NONRATT008453.2 on autophagy in genital tubercle fibroblasts of rats with hypospadias induced by dibutyl phthalate. Birth Defects Res. 113:399–408. 2021.PubMed/NCBI View Article : Google Scholar | |
Yu H, Yang J, Zhang Y, Fu H, Yan Z and Zhu Y: Vinclozolin-induced mouse penile malformation and ‘small testis’ via miR132, miR195a together with the Hippo signaling pathway. Toxicology. 460(152842)2021.PubMed/NCBI View Article : Google Scholar | |
Abbas TO, Elawad A, Pullattayil S AK and Pennisi CP: Quality of reporting in preclinical urethral tissue engineering studies: A systematic review to assess adherence to the ARRIVE guidelines. Animals (Basel). 11(2456)2021.PubMed/NCBI View Article : Google Scholar | |
Tan H, Wu G, Wang S, Lawless J, Sinn A, Chen D and Zheng Z: Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring. Birth Defects Res. 113:469–484. 2021.PubMed/NCBI View Article : Google Scholar | |
Tokat E, Yildiz Y, Eser PE, Kilinc MF and Doluoglu OG: Does intraurethral erythropoietin administration effect wound healing after hypospadias correction? An experimental rat study. Int Urol Nephrol. 53:2057–2062. 2021.PubMed/NCBI View Article : Google Scholar | |
Gulburun MA, Karabulut R, Turkyilmaz Z, Eryilmaz S, Kaya C, Arslan B, Gulbahar O, Poyraz A and Sonmez K: Protective effects of hydrogen rich saline solution on ventral penile mathieu type flap with penile tourniquet application in rats. J Pediatr Urol. 17:292.e1–292.e7. 2021.PubMed/NCBI View Article : Google Scholar | |
Fruntelată R, Stoica GA, Ciobanu MO, Ciurea ME, Nica O and Stoica M: Retrospective study over the hypospadias surgery in a single tertiary center. Curr Health Sci J. 47:177–183. 2021.PubMed/NCBI View Article : Google Scholar | |
Raheem AA, Banihani O, Abasher A, Alotay A, Alyami FA, Alsaad TA, Alqarni N, Alsowayan O, Jamalalali YA, Alhuwaiti M, et al: Pediatric urology surgical practice in the time of COVID-19: Results from tertiary Saudi Arabia hospitals. Urol Ann. 13:397–404. 2021.PubMed/NCBI View Article : Google Scholar | |
Jurat R, Rahimi MT and Barolia R: Surgical outcomes and socio-demographic pattern of hypospadias patients treated in a tertiary care center in Kabul, Afghanistan. J Pediatr Urol. 17:674.e1–674.e7. 2021.PubMed/NCBI View Article : Google Scholar | |
Irene M, Osawa F, Kuria K and Lessan J: Magnitude of post-urethroplasty urinary tract infections in children with hypospadias at a tertiary hospital in Kenya. J Pediatr Urol. 17:518.e1–518.e5. 2021.PubMed/NCBI View Article : Google Scholar | |
Khan S, Tafweez R, Haider A and Yaqoob M: Spectrum of external genital anomalies in disorders of sex development at children hospital & institute of child health, Lahore, Pakistan. Pak J Med Sci. 37(244)2021.PubMed/NCBI View Article : Google Scholar | |
Ashwin Shekar P, Ansari MS, Yadav P and Srivastava A: Presentation, treatment and outcomes of pediatric anterior urethral strictures: 28 Years' experience from a referral center. J Pediatr Urol. 17:398.e1–398.e9. 2021.PubMed/NCBI View Article : Google Scholar | |
Wiener JS, Huck N, Blais AS, Rickard M, Lorenzo A, Di Carlo HNM, Mueller MG and Stein R: Challenges in pediatric urologic practice: A lifelong view. World J Urol. 39:981–991. 2021.PubMed/NCBI View Article : Google Scholar | |
Ács N, Mátrai Á and Kaposi A: First data from the new, unified database of the Hungarian case-control surveillance of congenital abnormalities. J Matern Fetal Neonatal Med. 34:2887–2892. 2021.PubMed/NCBI View Article : Google Scholar | |
Benavides E, Lupo PJ, Sosa M, Whitworth KW, Canfield MA, Langlois PH and Schraw JM: Urban-rural residence and birth defects prevalence in Texas: A phenome-wide association study. Pediatr Res. 91:1587–1594. 2022.PubMed/NCBI View Article : Google Scholar | |
Arulanandam B, Dorais M, Li P and Poenaru D: The burden of waiting: Wait times for pediatric surgical procedures in Quebec and compliance with national benchmarks. Can J Surg. 64:E14–E22. 2021.PubMed/NCBI View Article : Google Scholar | |
Karabay E, Karsiyakali N, Kayar K and Koseoglu H: Hypospadias surgery on YouTube: Is it valid? Minerva Pediatr (Torino). 73:236–242. 2021.PubMed/NCBI View Article : Google Scholar | |
Jones P, Rajasegaran A, Brassale S, Chen Y, Haslam R, Austin C and Seideman CA: Assessment of the educational value of distal hypospadias repair videos on YouTube. Urology. 159:28–32. 2022.PubMed/NCBI View Article : Google Scholar | |
Cheng JW, Fernandez N, Shnorhavorian M, Merguerian PA and Kieran K: Engagement of common pediatric urologic conditions on social media. J Pediatr Urol. 18:236.e1–236.e7. 2022.PubMed/NCBI View Article : Google Scholar | |
Ghidini F and Castagnetti M: Pediatric urology research in 2020: A bibliometric analysis of the top 100 most cited articles. Urologia. 89:474–480. 2022.PubMed/NCBI View Article : Google Scholar | |
Matta R and Schaeffer AJ: The top 100 cited articles in pediatric urology: A bibliometric analysis. J Pediatr Urol. 17:709.e1–709.e12. 2021.PubMed/NCBI View Article : Google Scholar | |
Doğan G and İpek H: The evolution of hypospadias publications: A bibliometric approach. Rev Int Androl. 19:224–233. 2021.PubMed/NCBI View Article : Google Scholar | |
Leitao Braga B, Lisboa Gomes N, Nishi MY, Freire BL, Batista RL, D Faria Junior JA, Funari MFA, Figueredo Benedetti AF, de Moraes Narcizo A, Cavalca Cardoso L, et al: Variants in 46,XY DSD-related genes in syndromic and non-syndromic small for gestational age children with hypospadias. Sex Dev. 16:27–33. 2022.PubMed/NCBI View Article : Google Scholar | |
Niu HL, Yi P, Gao Q, Wang FH, Chen ZR, Li LP, Xia JQ, Cao Y and Zeng RX: Gonadal neoplastic related lesions in children with disorders of sexual development: A clinicopathological study of twelve cases. Zhonghua Bing Li Xue Za Zhi. 50:1145–1150. 2021.PubMed/NCBI View Article : Google Scholar : (In Chinese). | |
Phillips L, Lundholm C, Örtqvist L, Almqvist C, Nordenskjöld A and Skarin Nordenvall A: Fertility in men with hypospadias: A nationwide register-based study using dizygotic twinning rates as an indicator of semen quality. Andrology. 9:810–816. 2021.PubMed/NCBI View Article : Google Scholar |