Lateral ventricle chordoid meningioma presenting with inflammatory syndrome in an adult male: A case report

Hu,Yanyan; Zhang,Shizhong; Ye,Hong; Wang,Guojun; Chen,Xiao; Zhang,Yanbo

doi:10.3892/etm.2023.11935

Lateral ventricle chordoid meningioma presenting with inflammatory syndrome in an adult male: A case report

Authors:
- Yanyan Hu
- Shizhong Zhang
- Hong Ye
- Guojun Wang
- Xiao Chen
- Yanbo Zhang
View Affiliations

Affiliations: Department of Neurology, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong 271016, P.R. China, Department of Neurosurgery, The Affiliated Taian City Central Hospital of Qingdao University, Taian, Shandong 271000, P.R. China, Department of Pathology, The Affiliated Taian City Central Hospital of Qingdao University, Taian, Shandong 271000, P.R. China
Published online on: April 3, 2023 https://doi.org/10.3892/etm.2023.11935
Article Number: 236
Copyright: © Hu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Chordoid meningioma (CM) is a rare type of intracranial tumor. Intraventricular CM presenting with inflammatory syndrome is also rare. Meningioma is uncommonly accompanied by fever. The present case report documents a 28‑year‑old male who was admitted to the Affiliated Taian City Central Hospital of Qingdao University (Taian, China) with a 7‑day history of unexplained fever and a 3‑day history of progressive headache, which was accompanied with blurred vision in the right eye. Laboratory findings revealed an inflammatory condition with increased C‑reactive protein levels, elevated erythrocyte sedimentation rate and moderate leukocytosis. MRI also revealed a lesion located in the right lateral ventricle. Subsequently, the tumor was excised through the right transtrigone lateral ventricle route and the tumor was then completely removed. H&E staining revealed characteristic cords of meningeal epithelial cells embedded in a prominent myxoid background, with numerous lymphocytes and plasma cells surrounding the tumor. Immunohistochemical analysis indicated focal positive staining for epithelial membrane antigen and S100, and negative staining for glial fibrillary acidic protein. Following pathological examination, the tumor was identified to be a CM. During the early postoperative course, the clinical symptoms disappeared and the hematological values returned to normal. No evidence of tumor recurrence was observed after 24 months of follow‑up. To the best of our knowledge, the present study was the second to report the case of an adult patient with lateral ventricle CM presenting with inflammatory syndrome and it was the first case in an adult male.

View Figures

View References

1	Kepes JJ, Chen WY, Connors MH and Vogel FS: ‘Chordoid’ meningeal tumors in young individuals with peritumoral lymphoplasmacellular infiltrates causing systemic manifestations of the Castleman syndrome. A report of seven cases. Cancer. 62:391–406. 1988.PubMed/NCBI View Article : Google Scholar
2	Couce ME, Aker FV and Scheithauer BW: Chordoid meningioma: A clinicopathologic study of 42 cases. Am J Surg Pathol. 24:899–905. 2000.PubMed/NCBI View Article : Google Scholar
3	Tena-Suck ML, Collado-Ortìz MA, Salinas-Lara C, García-López R, Gelista N and Rembao-Bojorquez D: Chordoid meningioma: A report of ten cases. J Neurooncol. 99:41–48. 2010.PubMed/NCBI View Article : Google Scholar
4	Lin JW, Ho JT, Lin YJ and Wu YT: Chordoid meningioma: A clinicopathologic study of 11 cases at a single institution. J Neurooncol. 100:465–473. 2010.PubMed/NCBI View Article : Google Scholar
5	Lui PC, Chau TK, Wong SS, Lau PP, Tse GM, Thomas TM and Ng HK: Cytology of chordoid meningioma: A series of five cases with emphasis on differential diagnoses. J Clin Pathol. 60:1024–1028. 2007.PubMed/NCBI View Article : Google Scholar
6	Epari S, Sharma MC, Sarkar C, Garg A, Gupta A and Mehta VS: Chordoid meningioma, an uncommon variant of meningioma: A clinicopathologic study of 12 cases. J Neurooncol. 78:263–269. 2006.PubMed/NCBI View Article : Google Scholar
7	Choy W, Ampie L, Lamano JB, Kesavabhotla K, Mao Q, Parsa AT and Bloch O: Predictors of recurrence in the management of chordoid meningioma. J Neurooncol. 126:107–116. 2016.PubMed/NCBI View Article : Google Scholar
8	Di Ieva A, Laiq S, Nejad R, Schmitz EM, Fathalla H, Karamchandani J, Munoz DG and Cusimano MD: Chordoid meningiomas: Incidence and clinicopathological features of a case series over 18 years. Neuropathology. 35:137–147. 2015.PubMed/NCBI View Article : Google Scholar
9	Mawrin C and Perry A: Pathological classification and molecular genetics of meningiomas. J Neurooncol. 99:379–391. 2010.PubMed/NCBI View Article : Google Scholar
10	Jie D, Liu Z, He W, Wang S, Teng H and Xu J: Clinical features, radiological findings, and prognostic factors for primary intracranial chordoid meningioma. Front Neurol. 13(1002088)2022.PubMed/NCBI View Article : Google Scholar
11	Yang Y, Li D, Cao XY, Hao SY, Wang L, Wu Z and Zhang JT: Clinical features, treatment, and prognostic factors of chordoid meningioma: Radiological and pathological features in 60 cases of chordoid meningioma. World Neurosurg. 93:198–207. 2016.PubMed/NCBI View Article : Google Scholar
12	Cushing H and Eisenhardt L: Meningiomas, their classification, regional behaviour, life history, and surgical end results. Springfield, IL, Charles C Thomas, 1938.
13	Rohringer M, Sutherland GR, Louw DF and Sima AA: Incidence and clinicopathological features of meningioma. J Neurosurg. 71:665–672. 1989.PubMed/NCBI View Article : Google Scholar
14	Song KS, Park SH, Cho BK, Wang KC, Phi JH and Kim SK: Third ventricular chordoid meningioma in a child. J Neurosurg Pediatr. 2:269–272. 2008.PubMed/NCBI View Article : Google Scholar
15	Arima T, Natsume A, Hatano H, Nakahara N, Fujita M, Ishii D, Wakabayashi T, Doyu M, Nagasaka T and Yoshida J: Intraventricular chordoid meningioma presenting with Castleman disease due to overproduction of interleukin-6. Case report. J Neurosurg. 102:733–737. 2005.PubMed/NCBI View Article : Google Scholar
16	Wilson JL, Ellis TL and Mott RT: Chordoid meningioma of the third ventricle: A case report and review of the literature. Clin Neuropathol. 30:70–74. 2011.PubMed/NCBI View Article : Google Scholar
17	Nambiar A, Pillai A, Parmar C and Panikar D: Intraventricular chordoid meningioma in a child: Fever of unknown origin, clinical course, and response to treatment. J Neurosurg Pediatr. 10:478–481. 2012.PubMed/NCBI View Article : Google Scholar
18	Sadashiva N, Poyuran R, Mahadevan A, Bhat DI, Somanna S and Devi BI: Chordoid meningioma: A clinico-pathological study of an uncommon variant of meningioma. J Neurooncol. 137:575–582. 2018.PubMed/NCBI View Article : Google Scholar
19	Wind JJ, Jones RV and Roberti F: Fourth ventricular chordoid meningioma. J Clin Neurosci. 17:1301–1303. 2010.PubMed/NCBI View Article : Google Scholar
20	Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P and Ellison DW: The 2016 world health organization classification of tumors of the central nervous system: A summary. Acta Neuropathol. 131:803–820. 2016.PubMed/NCBI View Article : Google Scholar
21	Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW and Kleihues P: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 114:97–109. 2007.PubMed/NCBI View Article : Google Scholar
22	Wang XQ, Mei GH, Zhao L, Li ST, Gong Y, Zhong J, Chen H and Jiang CC: Clinical features and treatment of intracranial chordoid meningioma: A report of 30 cases. Histopathology. 62:1002–1017. 2013.PubMed/NCBI View Article : Google Scholar
23	Hasegawa S, Yoshioka S, Urabe S and Kuratsu J: Rapidly enlarging chordoid meningioma with abundant mucin production. Neuropathology. 26:438–441. 2006.PubMed/NCBI View Article : Google Scholar
24	Shih AR, Cote GM, Chebib I, Choy E, DeLaney T, Deshpande V, Hornicek FJ, Miao R, Schwab JH, Nielsen GP and Chen YL: Clinicopathologic characteristics of poorly differentiated chordoma. Mod Pathol. 31:1237–1245. 2018.PubMed/NCBI View Article : Google Scholar
25	Dohrmann GJ and Collias JC: Choroid plexus carcinoma. J Neurosurg. 43:225–232. 1975.PubMed/NCBI View Article : Google Scholar
26	Ellis TS, Schwartz A, Starr JK and Riedel CJ: Epithelioid hemangioendothelioma of the lumbar vertebral column: case report and review of literature. Neurosurgery. 38:402–407. 1996.PubMed/NCBI View Article : Google Scholar
27	Denaro L, Di Rocco F, Gessi M, Lauriola L, Lauretti L, Pallini R, Fernandez E and Maira G: Pyrogenic cytokine interleukin-6 expression by a chordoid meningioma in an adult with a systemic inflammatory syndrome. Case report and review of the literature. J Neurosurg. 103:555–558. 2005.PubMed/NCBI View Article : Google Scholar
28	Cassereau J, Lavigne C, Michalak-Provost S, Ghali A, Dubas F and Fournier HD: An intraventricular clear cell meningioma revealed by an inflammatory syndrome in a male adult: A case report. Clin Neurol Neurosurg. 110:743–746. 2008.PubMed/NCBI View Article : Google Scholar
29	Prokopienko M, Wierzba-Bobrowicz T, Grajkowska W, Stępień T and Sobstyl M: Chordoid meningioma. Case report and review of the literature. Niger J Clin Pract. 25:1–4. 2022.PubMed/NCBI View Article : Google Scholar
30	Tahta A, Genc B, Cakir A and Sekerci Z: Chordoid meningioma: Report of 5 cases and review of the literature. Br J Neurosurg. 37:41–44. 2023.PubMed/NCBI View Article : Google Scholar