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Review Open Access

Links between trauma and psychosis (Review)

  • Authors:
    • Ioanna Giannopoulou
    • Stelios Georgiades
    • Maria-Ioanna Stefanou
    • Demetrios A. Spandidos
    • Emmanouil Rizos
  • View Affiliations / Copyright

    Affiliations: Second Department of Psychiatry, Attikon University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece, Department of Basic Clinical Sciences, Medical School, University of Nicosia, 2415 Nicosia, Cyprus, Second Department of Neurology, School of Medicine, Attikon University General Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece, Laboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece
    Copyright: © Giannopoulou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 386
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    Published online on: June 28, 2023
       https://doi.org/10.3892/etm.2023.12085
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Abstract

The relationship between trauma and psychosis is complex and multifaceted, with evidence suggesting that trauma can be both a risk factor for the development of psychosis and a consequence of psychotic experiences. The present review aimed to provide an overview of the current state of knowledge on the relationship between trauma and psychosis, including historical and conceptual considerations, as well as epidemiological evidence. The potential explanation of the link between trauma and psychosis is provided through available models and similarities in their neurobiological associations. Overall, the research confirms the relationship between trauma and psychosis, and suggests that individuals with a co‑occurring history of trauma and psychosis may have increased symptom severity and worse functional outcomes compared with individuals with psychosis alone. Future research should focus on elucidating the underlying causal pathways between trauma exposure and psychosis in order to inform effective treatment approaches aiming to prevent the intensification of psychotic symptoms and processes.
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Copy and paste a formatted citation
Spandidos Publications style
Giannopoulou I, Georgiades S, Stefanou M, Spandidos DA and Rizos E: Links between trauma and psychosis (Review). Exp Ther Med 26: 386, 2023.
APA
Giannopoulou, I., Georgiades, S., Stefanou, M., Spandidos, D.A., & Rizos, E. (2023). Links between trauma and psychosis (Review). Experimental and Therapeutic Medicine, 26, 386. https://doi.org/10.3892/etm.2023.12085
MLA
Giannopoulou, I., Georgiades, S., Stefanou, M., Spandidos, D. A., Rizos, E."Links between trauma and psychosis (Review)". Experimental and Therapeutic Medicine 26.2 (2023): 386.
Chicago
Giannopoulou, I., Georgiades, S., Stefanou, M., Spandidos, D. A., Rizos, E."Links between trauma and psychosis (Review)". Experimental and Therapeutic Medicine 26, no. 2 (2023): 386. https://doi.org/10.3892/etm.2023.12085
Copy and paste a formatted citation
x
Spandidos Publications style
Giannopoulou I, Georgiades S, Stefanou M, Spandidos DA and Rizos E: Links between trauma and psychosis (Review). Exp Ther Med 26: 386, 2023.
APA
Giannopoulou, I., Georgiades, S., Stefanou, M., Spandidos, D.A., & Rizos, E. (2023). Links between trauma and psychosis (Review). Experimental and Therapeutic Medicine, 26, 386. https://doi.org/10.3892/etm.2023.12085
MLA
Giannopoulou, I., Georgiades, S., Stefanou, M., Spandidos, D. A., Rizos, E."Links between trauma and psychosis (Review)". Experimental and Therapeutic Medicine 26.2 (2023): 386.
Chicago
Giannopoulou, I., Georgiades, S., Stefanou, M., Spandidos, D. A., Rizos, E."Links between trauma and psychosis (Review)". Experimental and Therapeutic Medicine 26, no. 2 (2023): 386. https://doi.org/10.3892/etm.2023.12085
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