Open Access

Hantavirus infections in the South‑Eastern European countries: A study of two cases and literature review

  • Authors:
    • Gabriela Lupușoru
    • Andreea Gabriella Andronesi
    • Mircea Lupușoru
    • Ioana Ailincăi
    • Ruxandra Sfeatcu
    • Ileana Văcăroiu
    • Mihaela Banu
    • Camelia Achim
    • Gener Ismail
  • View Affiliations

  • Published online on: July 21, 2023     https://doi.org/10.3892/etm.2023.12129
  • Article Number: 430
  • Copyright: © Lupușoru et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Hantavirus infection is a rare zoonosis in South‑Eastern Europe. Depending on the serotype involved, the virus can cause hemorrhagic fever with renal syndrome which is also known as endemic nephropathy, and cardiopulmonary syndrome. Prompt diagnosis of the disease is essential for reducing the risk of severe manifestations and complications like chronic kidney disease, secondary hypertension or even death because there is no specific treatment or vaccine approved. The present study reported two cases of hemorrhagic fever with renal syndrome diagnosed in the Department of Nephrology of The Fundeni Clinical Institute (Romania). In both patients, kidney needle biopsy played a major role in establishing the diagnosis. The difficulties encountered in diagnosing this disease were also emphasized, taking into consideration the rarity of this infection in South‑Eastern Europe. The key literature data on the epidemiology, pathogenesis and management of this infection were further reviewed.
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September-2023
Volume 26 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Lupușoru G, Andronesi AG, Lupușoru M, Ailincăi I, Sfeatcu R, Văcăroiu I, Banu M, Achim C and Ismail G: Hantavirus infections in the South‑Eastern European countries: A study of two cases and literature review. Exp Ther Med 26: 430, 2023
APA
Lupușoru, G., Andronesi, A.G., Lupușoru, M., Ailincăi, I., Sfeatcu, R., Văcăroiu, I. ... Ismail, G. (2023). Hantavirus infections in the South‑Eastern European countries: A study of two cases and literature review. Experimental and Therapeutic Medicine, 26, 430. https://doi.org/10.3892/etm.2023.12129
MLA
Lupușoru, G., Andronesi, A. G., Lupușoru, M., Ailincăi, I., Sfeatcu, R., Văcăroiu, I., Banu, M., Achim, C., Ismail, G."Hantavirus infections in the South‑Eastern European countries: A study of two cases and literature review". Experimental and Therapeutic Medicine 26.3 (2023): 430.
Chicago
Lupușoru, G., Andronesi, A. G., Lupușoru, M., Ailincăi, I., Sfeatcu, R., Văcăroiu, I., Banu, M., Achim, C., Ismail, G."Hantavirus infections in the South‑Eastern European countries: A study of two cases and literature review". Experimental and Therapeutic Medicine 26, no. 3 (2023): 430. https://doi.org/10.3892/etm.2023.12129