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Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review

  • Authors:
    • Jianhang Wu
    • Junfa Sheng
    • Xiaoying Wu
    • Qiumei Wu
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasound, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian 350000, P.R. China
    Copyright: © Wu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 453
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    Published online on: August 3, 2023
       https://doi.org/10.3892/etm.2023.12152
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Abstract

At present, there are currently no reliable and consistent conclusions regarding transvaginal ultrasound assessment of endometrial receptivity in predicting clinical pregnancy outcomes of in vitro fertilization‑embryo transfer (IVF‑ET). Thus, in the present study, a meta‑analysis was performed on multiple endometrial receptivity indices detected by vaginal ultrasound, aiming to provide a diagnostic basis for clinical practice. PubMed, Embase, and Cochrane Library databases were searched for studies published between the establishment of the databases through to January 2023. Studies that reported infertile women undergoing IVF‑ET and undergoing vaginal ultrasound were included, but repeat publication, studies where the full text was not obtainable, studies where there was incomplete information provided or data extraction was not possible, studies on animals, case reports, reviews, and systematic reviews were excluded. STATA 15.1 was used to analyze the data. The pooled results showed that the endometrial thickness [Weighted mean difference (WMD)=0.03, 95% CI: 0.00‑0.06; P=0.022] and endometrial volume (WMD=0.41, 95% CI: 0.07‑0.74; P=0.017) of the pregnancy group after receiving IVF‑ET were all significantly higher than that of the non‑pregnancy group. The pooled results also showed that the vascularization index (VI) (WMD=0.79, 95% CI: 0.56‑1.03; P=0.000), flow index (FI) (WMD=1.82, 95% CI: 0.83‑2.81; P=0.000) and vascularization flow index (VFI) (WMD=1.58, 95% CI: 0.91‑2.24; P=0.000) of the pregnancy group after receiving IVF‑ET was significantly higher than that of the non‑pregnancy group. Systolic/diastolic (S/D) (WMD=‑4.92, 95%CI: ‑8.28‑ ‑1.56; P=0.004) of the uterine artery of the pregnancy group after receiving IVF‑ET was significantly lower than that of the non‑pregnancy group. However, the differences between the resistance index (RI) and pulsatility index (PI) in the pregnancy group vs. the non‑pregnancy group after receiving IVF‑ET were not statistically significant. Vaginal ultrasound can be used to predict the outcomes of pregnancy in infertile women undergoing IVF‑ET by measuring the thickness and volume of the endometrium, combined with the S/D, VI, FI, and VFI of the uterine artery.
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Copy and paste a formatted citation
Spandidos Publications style
Wu J, Sheng J, Wu X and Wu Q: Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review. Exp Ther Med 26: 453, 2023.
APA
Wu, J., Sheng, J., Wu, X., & Wu, Q. (2023). Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review. Experimental and Therapeutic Medicine, 26, 453. https://doi.org/10.3892/etm.2023.12152
MLA
Wu, J., Sheng, J., Wu, X., Wu, Q."Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review". Experimental and Therapeutic Medicine 26.3 (2023): 453.
Chicago
Wu, J., Sheng, J., Wu, X., Wu, Q."Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review". Experimental and Therapeutic Medicine 26, no. 3 (2023): 453. https://doi.org/10.3892/etm.2023.12152
Copy and paste a formatted citation
x
Spandidos Publications style
Wu J, Sheng J, Wu X and Wu Q: Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review. Exp Ther Med 26: 453, 2023.
APA
Wu, J., Sheng, J., Wu, X., & Wu, Q. (2023). Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review. Experimental and Therapeutic Medicine, 26, 453. https://doi.org/10.3892/etm.2023.12152
MLA
Wu, J., Sheng, J., Wu, X., Wu, Q."Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review". Experimental and Therapeutic Medicine 26.3 (2023): 453.
Chicago
Wu, J., Sheng, J., Wu, X., Wu, Q."Ultrasound‑assessed endometrial receptivity measures for the prediction of in vitro fertilization‑embryo transfer clinical pregnancy outcomes: A meta‑analysis and systematic review". Experimental and Therapeutic Medicine 26, no. 3 (2023): 453. https://doi.org/10.3892/etm.2023.12152
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