Congenital factor XI deficiency with multiple tooth extractions (Case report)

Kato,Tomoki; Yamada,Michihiro; Watanabe,Takuma; Yamanaka,Shigeki; Fukuhara,Shizuko; Nakao,Kazumasa

doi:10.3892/etm.2023.12208

November-2023 Volume 26 Issue 5

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November-2023 Volume 26 Issue 5

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Case Report

Congenital factor XI deficiency with multiple tooth extractions (Case report)

Authors:
- Tomoki Kato
- Michihiro Yamada
- Takuma Watanabe
- Shigeki Yamanaka
- Shizuko Fukuhara
- Kazumasa Nakao
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Affiliations: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606‑8507, Japan
Article Number: 509
|
Published online on: September 15, 2023

https://doi.org/10.3892/etm.2023.12208
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Abstract

Congenital factor XI deficiency (CFXI) is a rare blood disorder that occurs in one of every one million individuals. Given its rarity, there are very few reports of surgical procedures performed in the oral region CFXI patients. The present study reports the case of a 43‑year‑old man with CFXI who experienced multiple tooth extractions. It also conducted a review of the literature and treatment outline. We preoperatively administered fresh frozen plasma (FFP) before the tooth extraction and continued to transfuse FFP at the rate of 2 units per day from day 1 to 4 of admission. The extractions were divided into two parts, maxillary and mandibular and the teeth extracted on days 2 and 4 of admission. The patient was discharged on day 6 of admission because there was good progress and no postoperative bleeding. Therefore, it was possible to perform multiple tooth extractions without abnormal bleeding in the oral cavity; the chance of bleeding was reduced by administering FFP and increasing local hemostasis in CFXI patients.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Congenital factor XI deficiency with multiple tooth extractions (Case report)

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